Research Spotlight: Gene Therapy Improves Brain Function in Lab Models of Mucolipidosis IV
Mucolipidosis IV (MLIV) is a rare neurologic disease of childhood with extremely high unmet need.
Mucolipidosis IV (MLIV) is a rare neurologic disease of childhood with extremely high unmet need.
The locus coeruleus is a key brain structure implicated in cognitive function and neurodegenerative disease.
Sneha Saxena,PhD, is lead author of a recently published article in Molecular Cell, Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells.
The NeuroLaw Library is a free, open access repository for those involved in the juvenile and adult criminal justice system in need of accurate and applicable neuroscience resources.
MGH’s Age Positively Program, a partnership between the Geriatric Medicine and Infectious Diseases divisions, provides care and resources to enhance the care and well-being of people with HIV as they age.
The findings could lead to new strategies to treat metastatic cancer and would be particularly impactful for patients with pancreatic cancer.
The new discovery provides a potential therapeutic target to prevent permanent scarring in human hearts, allowing heart cells to regenerate.
Immune activation in a pregnant woman can occur in response to metabolic diseases like obesity, infections in pregnancy, exposure to pollution and environmental toxins, or even stress and can have negative effects on fetal brain immune cells (microglia).
Paul Lerou, MD, chief, Newborn Medicine, Mass General for Children (MGfC), and Sergei Roumiantsev, MD, associate chief, MGfC Division of Newborn Medicine, have been working to improve capacity challenges since 2015.
On June 9, 2024, mother of three Kelli Shaw celebrated her 10-year wedding anniversary with a vow renewal ceremony. It is a milestone she nearly did not live to see following a medical emergency less than a year ago.
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