Faculty List
Monday, April 24
11:00-1:00	Check-In (West Tower, Pre-Assembly, Grand Ballroom)
1:00-1:05	Opening Remarks: Roger J. Hajjar
1:05-1:40	Elizabeth G. Nabel (OPENING SPEAKER): The promise of cardiovascular stem cell therapies: an investment by the NHLBI.
1:40-3:20	Session 1: Stem Cells I: Pluripotent Cells (Chairs: James Wilson, Michael Schneider)
1:40	James Wilson: Novel viruses as vectors for in vivo gene transfer.
2:05	Christine Mummery:  Cardiomyocytes from human embryonic stem cells.
2:30	Piero Anversa:  Cardiac stem cells.
2:55	Michael Schneider: Genome-wide analysis of Wnt- and BMP-dependent genes during cardiac myogenesis in pluripotent mouse cells.
3:20-3:35	Break + Poster Viewing: (Grand Ballroom A)
3:35-5:15	Session 2: Molecular Imaging and Engineering Technology (Chair: Paul Huang)
3:35	John Frangioni: Stem cell imaging
4:00	Zahi Fayad: Molecular imaging of atherosclerosis.
4:25	David Sosnovik: Molecular MRI of myocardial injury and repair.
4:50	Sangeeta Bhatia: Microscale tissue engineering.
5:15-6:00	Poster Viewing (Grand Ballroom A)
6:45-7:30	Reception/Dinner ~ $75 per guest Cocktails (Skyline Suites)
7:30-9:30	Opening Dinner (Skyline Suites)
Tuesday, April 25
8:00-10:15	Session 3: Stem Cells - State of the Art (Chairs: Ken Chien, David Scadden)
8:00	TBA
8:35	George Daley: Modeling hematopoietic transplantation with ES cells.
9:00	Leonard Zon: Induction of blood stem cells in the zebrafish.
9:25	David Scadden: The stem cell niche as therapeutic target.
9:50	Ken Chien: Heart Like Blood: The islet-1 cardiovascular progenitor story.
10:15-10:30	Break + Poster Viewing (Grand Ballroom A)
10:30-12:10	Session 4: Stem Cells II: Endothelial Progenitor Cells (Chairs: Jonathon Epstein, Stephanie Dimmeler)
10:30	TBA
10:55	Jonathan Epstein: Deciphering neural crest pluripotency to model stem cell behavior.
11:20	Douglas Losordo: CD34 cell therapy for myocardial ischemia.
11:45	Karl-Ludwig Laugwitz: Isl1+ cardiac progenitors: a system to study cardiogenic signaling.
12:10-1:15	- Lunchtime (Skyline Suites) - Breakout Session (Grand Ballroom B): Gene & Cell Delivery Methods
	Roger Hajjar: Tracking cells and genes in the cardiovascular system. David Kaye: Cardiac gene delivery: towards clinical approaches.
1:15-2:30	Session 5: Viral Vectors (Chair: R. Jude Samulski)
1:15	Dawn Bowles: Haute couture vectors: Solving Clinical problems with custom designed AAV vectors.
1:40	R. Jude Samulski: Optimizing gene delivery for heart.
2:05	Xandra Breakefield: Imaging gene delivery.
2:30-2:45	Break & Poster Viewing (Grand Ballroom A)
2:45-4:50	Session 6: Targets I: Hypertrophy Signals (Chair: Howard Rockman)
2:45	Stefan Engelhardt: Regulation of cardiac growth.
3:10	Yibin Wang: Novel protein phosphatases in cardiac stress signaling.
3:35	Thomas Force: Growth signals co-opt Wnt pathway components to regulate cardiac development, growth, and hypertrophy.
4:00	Hunter Champion: Divergent roles for Rho A and Rho kinase in cardiac hypertrophy and heart failure.
4:25	Howard Rockman: New insights into heptahelical receptor signaling.
4:50	Break for the day.
Wednesday, April 26
8:00-9:15	Session 7: Stem Cells III: Grafting and Engineering Muscle Lineages (Chair: Charles Murry)
8:00	Charles Murry: Adult and embryonic stem cells in cardiac repair.
8:25	Thomas Eschenhagen: Engineering heart muscles from primary heart cells and stem cells.
8:50	Ronglih Liao: Mending a broken heart: cardiac progenitor cells for myocardial repair.
9:15-9:30	Break & Poster Viewing (Grand Ballroom A)
9:30-11:35	Session 8: Clinical Gene and Cell-Based Therapy (Chairs: Helmut Drexler, Eduardo Marban)
9:30	Helmut Drexler: BOOST I: Follow up and implications.
9:55	Stefanie Dimmeler: REPAIR - AMI: Results and implications.
10:20	Stefan Janssens: Autologous bone marrow cell transplantation after AMI: Lessons from (pre)clinical trials.
10:45	Eduardo Marban: Cardiosphere-derived stem cells for cardiac regeneration.
11:10	Roger Hajjar: Clinical gene therapy for heart failure.
11:35-11:45	Presentation: "CCGT3 Best Poster - Young Investigator Award"
11:45-12:50	- Lunchtime (Skyline Suites) - Breakout Session (Grand Ballroom B): NIH Programs in Gene & Cell Therapy
	Sonia Skarlatos: NHLBI Programs in Gene Therapy Stephen Mockrin: NHLBI/NIH programs in cell-based therapeutics.
12:50-2:30	Session 9: Targets II: Metabolic Targets and Protein Folding (Chairs: Kenneth Bloch, Robert Gerszten)
12:50	Bruce Spiegelman: PGC-1 coactivators and the control of energy homeostasis.
1:15	Daniel Kelly: Nuclear receptors as novel targets for cardiovascular therapeutics.
1:40	Federica del Monte: Protein misfolding in dialated cardiomyopathy.
2:05	Anne-Marie Lompré: SERCA gene transfer inhibits vascular smooth muscle cell proliferation through modulation of the NFAT pathway.
2:30-4:35	Session 10: Targets III: Excitation-Contraction Coupling (Chairs: Andrew Marks, Roger Hajjar)
2:30	Andrew Marks: Leaky ryanadine receptors in heart failure and sudden cardiac death.
2:55	Sian Harding: Cardioprotection through the beta2-adrenoceptor.
3:20	Christine Seidman: Mutations, calcium and cardiac remodeling.
3:45	Litsa Kranias: New insights into SR Ca-cycling and cardiac function.
4:10	Walter Koch: S100A1 and its role in heart failure.
4:35-4:50	Break & Poster Viewing (Grand Ballroom A)
4:50-6:30	Session 11: Targets IV: Apoptosis (Chairs: Gerald Dorn, Anthony Rosenzweig)
4:50	Anthony Muslin: Role of Akt and MAPks in cardiomyocyte growth and survival.
5:15	Gerald Dorn: Distinct essential functions of proapoptotic Nix and Bnip3: Individual and combined gene ablation.
5:40	Mark Sussman: Cardio "Akt"ive effects: a nucleus of survival signals, paracrine factors, and stem cells.
6:05	Anthony Rosenzweig: PI3-kinase-dependant signaling networks controlling cardiomyocytes survival and function.
6:30	Closing Remarks
6:35	Adjourn