Treatment Programs

Endometrial Cancer

The Gillette Center for Gynecologic Oncology offers women with endometrial cancer comprehensive, coordinated care supported by surgical innovation, research and clinical trials.

Endometrial cancer is the most common gynecologic cancer, forming in the tissue lining the uterus. For information on rare uterine sarcomas that begin in smooth muscle or connective tissue cells, see Uterine Sarcoma.

Experienced clinicians at the Gillette Center for Gynecologic Oncology provide multidisciplinary care for women with any stage of endometrial cancer, including recurrence.

Innovative Approaches

We treat thousands of women with gynecologic cancers annually, and studies show that such high-volume experience results in improved patient outcomes. Among the approaches offered here are:

  • Advanced diagnostics through imaging and pathology
  • Intraoperative radiation therapy
  • Robotic-assisted and minimally invasive surgeries
  • Advanced radiation therapy techniques, including technologies offered at only a few other centers nation wide
  • Access to leading-edge therapies through clinical trials conducted collaboratively with hospitals in the Harvard system and nationally with the Gynecologic Oncology Group

Multidisciplinary Patient Care Your personalized treatment plan will be developed by experts from an array of gynecologic cancer specialties. Depending on the stage and other characteristics of your cancer, this treatment plan may include surgery, chemotherapy, radiation, or a combination of these therapies.

The specialists involved in your care may include:

  • Pathologists specializing in gynecologic cancers who provide a precise diagnosis of your cancer.
  • Radiologists specializing in gynecologic malignancies that help guide the selection of appropriate imaging tests and provide accurate interpretation.
  • Surgical Oncologists experienced in the latest minimally-invasive gynecologic surgery approaches.
  • Medical Oncologists to prescribe the most effective chemotherapy treatments and discuss available clinical trials
  • Radiation Oncologists who specialize in delivering the highest therapeutic dose while protecting healthy tissue
  • Oncology nurses and nurse practitioners who specialize in cancer care
  • Oncology psychiatrists and social workers experienced in helping with the cognitive side effects of cancer and treatment, as well the emotional and spiritual aspects of the cancer experience
  • A nutritionist to help you with questions about diet and nutrition during treatment
  • Palliative care providers to improve quality of life

Members of your care team meet regularly with you and your referring physician to ensure clear communication and seamless coordination of care.

Gynecologic Oncology – Advanced Care for All Gynecologic Cancers at Mass General Hospital

Expertise in Diagnosing and Staging Cancers

Our pathologists are sub-specialized in identifying gynecologic malignancies. This expertise leads to more accurate diagnosis and staging, which forms the basis for your treatment.

Our gynecologic cancer pathologists are internationally recognized and consulted on the diagnosis of endometrial cancer. They participate in weekly tumor board meetings, sharing information about each patient’s unique cancer with the entire treatment team to help guide care planning.

Our skilled radiologists employ all the most advanced imaging methods and are well versed in performing image-guided interventional procedures such as CT-guided biopsy.

Advancing Care by Improving MedicineDetermining the right chemotherapeutic approach to treating your cancer depends on a detailed pathology report and your doctor’s ability to balance benefits and side effects based on your overall health and genetic markers of your disease. Patients treated here have the advantage of knowing their medical oncologist has cared for hundreds of women with the same type of disease as well as knowing that the resources of a major medical center are available to help them with any side effects that may arise.

Your medical oncologist may recommend traditional or novel approaches to treating your disease such as:

  • Hormone therapy
  • New combinations of chemotherapies
  • Biologic treatments
  • Clinical trials

Excellence in Surgical Care

Our gynecologic cancer surgeons are highly experienced in the treatment of gynecologic cancers and are recognized leaders in their fields. Research has shown that surgeons performing higher volumes of particular procedures can often offer patients better outcomes, such as shorter hospital stays and fewer complications. We offer the latest surgical innovations with emphasis on minimally invasive procedures.

These include:

  • Robotic-assisted and laparoscopic hysterectomy with surgical staging for patients with endometrial cancer; studies have shown this approach results in a quicker recovery and less postoperative discomfort
  • Comprehensive lymph node dissection to identify microscopic spread of cancer that otherwise might escape detection by imaging tests
  • Cytoreductive surgery techniques for women with advanced disease, which can result in a better long-term outcome

Pioneering Radiation TherapiesWe offer a full spectrum of radiation therapy treatments including some approaches available at just a few other medical centers in the United States:

  • Proton beam therapy for some women with endometrial and vulvar tumors
  • Intraoperative radiation therapy
  • Intensity modulated radiation therapy
  • Outpatient high-dose rate brachytherapy

Learn more about radiation therapy.

Improving Care through Clinical TrialsThe Gillette Center for Gynecologic Oncology is one of the nation's outstanding centers for clinical research in gynecologic malignancy. The center has had a strong leadership role at every level of development of therapies for women's cancers, including preclinical drug development and cooperative clinical trials.

Research has shown that women with widely metastatic endometrial cancer live longer without disease following aggressive cytoreductive surgery. Current research is focused on finding new ways to combine existing chemotherapies, sometimes with radiation treatments.

Find clinical trials for women with endometrial cancer.
Find Targeted Therapy Trials for endometrial cancer.

Developing Better Therapies through Research

Our translational research program focuses on understanding how endometrial cancer develops and progresses, how existing approaches can be better used to treat this disease, and on finding cancer-causing cellular processes that can be interrupted by therapeutic intervention.

Endometrial Cancer

Cancer of the endometrium, the most common cancer of the female reproductive organs, is a disease in which malignant (cancerous) cells are found in the endometrium. Endometrioid cancer is a specific type of endometrial cancer.

The Katherine A. Gallagher Integrative Therapies Program

The Katherine A. Gallagher Integrative Therapies Program focuses on improving the quality of life and well-being of Cancer Center patients, their families and friends through free wellness services such as acupuncture and yoga. These services help you take care of your whole self — mind, body and spirit.

Maxwell V. Blum Cancer Resource Room

The Maxwell V. Blum Cancer Resource Room at the Massachusetts General Hospital Cancer Center provides cancer patients and their families with information and resources for living with cancer.

The PACT Program

The Marjorie E. Korff PACT program at the Massachusetts General Hospital Cancer Center provides psycho-educational support for parents who are patients.

Oncology Chaplaincy

Our oncology chaplain is familiar with the unique needs of those with cancer.

Home Disconnect

A home infusion pump may be part of your treatment plan. In some cases, you may have the option for disconnecting the chemotherapy from home. If this option applies to you, and you would prefer to disconnect from home, this instructional video will reinforce the teaching provided to you by your nurse in the Mass General cancer Center

The following related clinical trials and research studies are currently seeking participants at Massachusetts General Hospital. Search for clinical trials and studies in another area of interest.

The Katherine A. Gallagher Integrative Therapies Program

The Katherine A. Gallagher Integrative Therapies Program focuses on improving the quality of life and well-being of Cancer Center patients, their families and friends through free wellness services such as acupuncture and yoga. These services help you take care of your whole self — mind, body and spirit.

Maxwell V. Blum Cancer Resource Room

The Maxwell V. Blum Cancer Resource Room at the Massachusetts General Hospital Cancer Center provides cancer patients and their families with information and resources for living with cancer.

The PACT Program

The Marjorie E. Korff PACT program at the Massachusetts General Hospital Cancer Center provides psycho-educational support for parents who are patients.

Oncology Chaplaincy

Our oncology chaplain is familiar with the unique needs of those with cancer.

Home Disconnect

A home infusion pump may be part of your treatment plan. In some cases, you may have the option for disconnecting the chemotherapy from home. If this option applies to you, and you would prefer to disconnect from home, this instructional video will reinforce the teaching provided to you by your nurse in the Mass General cancer Center

Cancer Center

55 Fruit Street
Boston, MA 02114

Phone: 617-726-5130

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Our approach to patient care unites cancer specialists across the hospital to create a personalized treatment plan for each patient, ensuring the best possible outcomes.

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Help our team at the Gillette Center for Gynecologic Oncology offer personalized and comprehensive care to women facing gynecologic cancers.