Andrew T. Chan, MD, MPH

• Epidemiology of colorectal cancer
• Chemoprevention of colorectal cancer
• Novel techniques in detection of colorectal neoplasia
• Epidemiology of gastrointestinal bleeding

Daniel Chung, MD

• Adenoma prevention with celecoxib
• Angiogenic profile of rectal cancer
• Genetics and other causes of cancer
• Sensitivity of the EXACT Panel in the detection of colorectal cancer

William Brugge

• Staging of gastro-intestinal malignancies with endosonography
• Endoscopic mucosal resection of early gastrointestinal malignancies

Norman Nishioka

• Clinical trial to optimize aminolevulinic acid-based photodynamic therapy of Barrett's esophagus.

Chin Hur

• Cost-effectiveness of the management of Barrett's esophagus +/- displasia: A Monte Carlo Markov model

Bruce Sands

• A Six-Week Randomized, Double-Blind, Controlled Trial of Asacol 6.0 g/day versus Asacol 3.2 g/day for the Treatment of Mild to Moderate Crohn's Disease. (B. Sands) See Protocol Summary (Internal access only)
• A Randomized Placebo-Controlled Trial of Rosiglitazone for Treatment of Ulcerative Colitis. (B. Sands) See Protocol Summary (Internal access only)
• Development of a Steroid-Specific Quality of Life Instrument for Patients with Inflammatory Bowel Disease. (B. Sands) See Protocol Summary (Internal access only)
• Identification of Susceptibility Genes in Inflammatory Bowel Disease.
• A Double-Blinded, Randomized, Parallel Arm, Dose Ranging Study of IMURAN in Subjects with Active Crohn's Disease Requiring Treatment with Prednisone (ACORDIS).
• Contact person: Stacey - 617-724-4301

Raymond Chung

• A randomized, controlled trial of IFN-alfa + ribavirin vs. PEG-IFN-alfa + ribavirin in the treatment of HCV in HIV-coinfected patients
• An analysis of risk factors for antiretroviral hepatotoxicity in HIV+ subjects
• Viral evolution in persons with HCV and HIV receiving highly active antiretroviral therapy
• A pilot study of postexposure prophylaxis in health care workers with occupational exposure to HCV
• Insulin resistance in post liver transplant HCV disease (R. Chung)
• A prospective study of insulin resistance in patients undergoing liver transplantation for HCV
• Observational database on patients who receive orthotopic liver transplantation for hepatitis B
• Clinical trial of lamivudine and perioperative IV hepatitis B imune globulin in the prevention of recurrent hepatitis B post-liver transplantation in low risk patients
• Randomized trial of lamivudine and intramuscular hepatitis B immune globulin vs. lamivudine monotherapy as maintenance prophylaxis against recurrent hepatitis B post-liver transplantation in high risk patients
• A multicenter study of acute liver failure
• A multicenter study of intraveous N-acetyl cysteine in the treatment of non-acetominophen related acute liver failure
• A phase I/II, double blind, dose escalation study to evaluate the safety, pharmacokinetics, and antiviral activity of val-mCyd (NM283) in adults with chronic Hepatitis C

Jules Dienstag

• The hepatitis C antiviral long-term treatment against cirrhosis (HALT-C): A randomized, controlled trial to evaluate the safety and efficacy of long-term peginterferon alpha-2a for treatment of chronic hepatitis C in subjects who failed to respond to previous interferon therapy

Andrea Reid

• Access of minorities with end-stage liver disease to orthotopic liver transplantation

Daniel Pratt, MD

• Viral Hepatitis
• Colorectal Liver Disease

Brad Kuo

• A Phase III. Multicenter Open Label, Extension Study to Evaluate the Long Term Safety of Renzapride 4mg Once Daily in Women with Constipation-Predominant Irritable Bowel Syndrom
• A Phase III, Multi-center, Randomized Double-Blind Placebo-Controlled Study of Renzapride in Women With constipation-Predominant Irritable Bowel Syndome
• CNS Phenotype Characterization of Patients with NERD
• A Phase II Study to Investigate the Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia
• fMRI Expectation Analgesia and Acupuncture in IBS
• GI Monitoring System with Gastric Emptying Determining Gastric Residence Time Using the Smartpill Capsule
• Assesment of Whole Gut Transit Time Using the SmartPill Capsule
• Nausea and Acupuncture (Sessions 1, 2 and 3)
• Defining Central Circuits of Visceral Pain

William Brugge

• Pancreatic cystadenomas: diagnosis and ablation with endosonography
• Ethanol ablation of pancreatic cystadenoma
• EUS guided injection of ethanol

William Brugge

• Evaluation and treatment of pancreatic pseudocysts
• EUS-guided Portal Vein Catheterization in Portal Hypertensive Patients
• A randomized trial comparing the uncovered to the covered wallstent in the palliation of malignant bile duct strictures

Bruce Sands

• Identification of Susceptibility Genes in Inflammatory Bowel Disease

Peter Kelsey, MD

• A prospective comparison of duodenoscope assisted cholangiopancreatoscopy (DACP) and endoscopic retrograde cholangiopancreatography (ERCP) to ERCP alone
• Contact person: Dr. Brenna Bounds 617-724-1685