Andrew T. Chan, MD, MPH

Assistant Professor of Medicine,
Harvard Medical School
Address: Massachusetts General Hospital
Blake 4
55 Fruit St.
Boston, MA 02114
Patient Appointments: (617) 726-3212
Fax: (617) 724-6832
E-Mail: achan@partners.org
Clinical Background:  
MD Degree: Harvard Medical School, 1997
Residency: Massachusetts General Hospital, 2000
Chief Residency: Massachusetts General Hospital, 2002
Fellowship: Massachusetts General Hospital, 2004
Other: Masters in Public Health,
Harvard School of Public Health, 2004
Board Certifications: Internal Medicine, 2000
GI, 2004
Clinical interests: Colorectal cancer
Gastrointestinal cancer
Familial GI Cancer syndromes (FAP, HNPCC)
Cancer prevention
General Gastroenterology
Research interests: Epidemiology of colorectal cancer
Chemoprevention
Genetic epidemiology
Novel techniques in early detection of colorectal cancer
Recent Publications:
  1. Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Wu K, Fuchs CS. Aspirin dose and duration of use and risk of colorectal cancer in men. Gastroenterology. 2008 Jan;134(1):21-8.

  2. Chan AT. Can Aspirin Prevent Colorectal Cancer? Lancet 2007; 369 (9573): 1577-1578.

  3. Chan AT, Ogino S, Fuchs CS. Aspirin and risk of colorectal cancer in relation to the expression of COX-2. N Engl J of Med 2007; 356: 2131-42.

  4. Chan AT, Manson JE, Feskanich D, Stampfer MJ, Colditz GA, Fuchs CS. Long-term aspirin use and mortality in women. Arch Int Med 2007; 167: 562-572.

  5. Chan AT, Manson JM, Albert CM, Chae CU, Rexrode KM, Curhan GS, Willet WC, Fuchs CS. Non-steroidal anti-inflammatory drugs, acetaminophen, and the risk of cardiovascular events. Circulation 2006; 113 (12): 1578-1587.

  6. Chan AT, Fuchs CS. Do cyclo-oxygenase-2 inhibitors increase the risk of cardiovascular events? Nature Clinical Practice Oncology 2005; 2(9): 434-435.

  7. Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Curhan GC, Fuchs CS. Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA. 2005 Aug 24;294(8):914-23.

  8. Chan AT, Ma J, Tranah GJ, Giovannucci EL, Rifai N, Hunter DJ, Fuchs CS. Hemochromatosis gene mutations, body iron stores, dietary iron, and risk of colorectal adenoma in women. J Natl Cancer Inst. 2005 Jun 15;97(12):917-26.

  9. Tranah GJ, Chan AT, Giovannucci E, Ma J, Fuchs C, Hunter DJ. Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study. Mol Carcinog. 2005 Sep;44(1):21-30.

  10. Chan AT, Tranah GJ, Giovannucci EL, Hunter DJ, Fuchs CS. Genetic variants in the UGT1A6 enzyme, aspirin use, and the risk of colorectal adenoma. J Natl Cancer Inst. 2005 Mar 16;97(6):457-60.

  11. Chan AT, Tranah GJ, Giovannucci EL, Willett WC, Hunter DJ, Fuchs CS. Prospective study of N-acetyltransferase-2 genotypes, meat intake, smoking and risk of colorectal cancer. Int J Cancer. 2005 Jul 1;115(4):648-52.

  12. Chan AT, Tranah GJ, Giovannucci EL, Hunter DJ, Fuchs CS. A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma. Clin Gastroenterol Hepatol. 2004 Aug;2(8):704-12.

  13. Chan AT, Giovannucci EL, Schernhammer ES, Colditz GA, Hunter DJ, Willett WC, Fuchs CS. A prospective study of aspirin use and the risk for colorectal adenoma. Ann Intern Med. 2004 Feb 3;140(3):157-66.

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