Ramnik Xavier, MD

Assistant Professor in Medicine
Harvard Medical School
Address: Massachusetts General Hospital
Blake 4
55 Fruit St.
Boston, MA 02114
Patient Appointments: (617) 724-6007
Academic Phone: (617) 643-3331
Fax: (617) 724-6832
Clinical Background:
MD Degree: University of Zimbabwe, Godfrey Huggins School of Medicine, 1986
Residency: Massachusetts General Hospital, 1992
Fellowship: Massachusetts General Hospital, 1996
Board Certifications: Internal Medicine, 1993
Gastroenterology, 1995
Clinical Interests: ulcerative colitis, crohn's disease, celiac disease, autoimmune liver disease
Recent Publications:
  1. Khokhlatchev A, Rabizadeh S, Xavier R, Nedwidek M, Chen T, Zhang X, Seed B, Avruch J. Identification of a novel ras-regulated proapoptotic pathway. Curr Biol. 2002 Feb 19;12(4):253-65.

  2. Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, Carrion D, Xu H, Schorle H, Kobler JB, Scambler P, Wynshaw-Boris A, Skoultchi AI, Morrow BE, Kucherlapati R. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 2001 Feb 23;104(4):619-29.

  3. Xavier R, Seed B. Related Articles Membrane compartmentation and the response to antigen. Curr Opin Immunol. 1999 Jun;11(3):265-9.

  4. Fukumura D, Xavier R, Sugiura T, Chen Y, Park EC, Lu N, Selig M, Nielsen G, Taksir T, Jain RK, Seed B. Tumor induction of VEGF promoter activity in stromal cells. Cell. 1998 Sep 18;94(6):715-25.

  5. Xavier R, Brennan T, Li Q, McCormack C, Seed B. Related Articles Membrane compartmentation is required for efficient T cell activation. Immunity. 1998 Jun;8(6):723-32.

  6. Swat W, Fujikawa K, Ganiatsas S, Yang D, Xavier RJ, Harris NL, Davidson L, Ferrini R, Davis RJ, Labow MA, Flavell RA, Zon LI, Alt FW. SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. Immunity. 1998 May;8(5):625-34.

  7. Mankin HJ, Rosenthal DI, Xavier R. Gaucher disease. New approaches to an ancient disease. J. Bone Joint Surg Am. 2001 May;83-A(5):748-62.

  8. Beck PL, Xavier R, Lu N, Nanda NN, Dinauer M, Podolsky DK, Seed B. Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Gastroenterology. 2000 Sep;119(3):699-705.