Thursday, July 20, 2017

Setting the Record Straight: PPIs Do Not Cause Dementia

New Gastroenterology research finds no convincing evidence to support the suggestion that proton-pump inhibitor (PPI) use increases dementia risk

Several studies have reported associations between proton-pump inhibitor (PPI) use and dementia. New research published on July 18 in Gastroenterology, the official journal of the American Gastroenterological Association (AGA), puts these claims to rest. The study authors report that there is no convincing evidence to support the suggestion that PPI use increases dementia risk. These findings are based on an analysis of 13,864 participants from the Nurses’ Health Study II who completed testing on cognitive function, which is key predictor of the risk of dementia later in life.

Link to full AGA release on study led by MGH investigator Andrew Chan, MD, MPH.

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