Massachusetts General Hospital

Biography

Dr. MacLean is a board certified allergist / immunologist. He sees patients with any of the following cnoditions

• Allergic Rhinitis (allergies including hay fever)
• Asthma and related disorders
• Chronic urticaria (hives) and angioedema
• Drug Allergy (adverse reactions to medication)
• Food Allergy
• Sinusitis
• Stinging insect allergy
• Nasal Polyps
• Non-HIV immune deficiency disorders

Publications

1. Silverman ES, De Sanctis GT, Boyce J, Maclean JA, Jiao A, Green FH, Grasemann H, Faunce D, Fitzmaurice G, Shi GP, Stein-Streilein J, Milbrandt J, Collins T, Drazen JM. The transcription factor early growth-response factor 1 modulates tumor necrosis factor-alpha, immunoglobulin E, and airway responsiveness in mice. Am J Respir Crit Care Med 2001;1;163(3):778-85.

2. Mathew A, MacLean JA, DeHaan E, Tager AM, Green FHY, Luster AD. Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation. J. Exp. Med. 2001;193:1087-96

3. MacLean JA, Eidelman FJ. The Genetics of Atopy and Atopic Eczema. Arch Dermatol 2001;137(11):1474-76.

4. Medoff BD, Sauty A, Tager AM, Maclean JA, Smith RN, Mathew A, Dufour JH, Luster AD. IFN-gamma-inducible protein 10 (CXCL10) contributes to airway hyperreactivity and airway inflammation in a mouse model of asthma. J Immunol 2002;15;168(10):5278-86.

5. MacLean JA, Hannaway PJ. Angioedema and AT1 receptor blockers: proceed with caution. Arch Intern Med. 2003;23;163(12). 

6. Ober AI, MacLean JA, Hannaway PJ.Life-threatening anaphylaxis to venom immunotherapy in a patient taking an angiotensin-converting enzyme inhibitor. J Allergy Clin Immunol. 2003;112(5):1008-9.
 
7. MacLean, JA. Wheezing and asthma: When to refer for an allergy evaluation. J. Respir. Dis Pediatrician. 2003;5(4):153-58.

In General: James M. Perrin, MD

In General awards and honors