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Dr. Nozari is currently Division Chief of Orthopedic Anesthesia and an Associate Professor of Anaesthesia at Harvard Medical School. He is a trained anesthesiologist and intensivist from Uppsala Univeristy in Sweden, and came to Boston in 2003 from the University of Pittsburgh Safar Center, where he worked with Peter Safar on Resuscitation Research. He has authored over 40 peer review publications and many book chapters in resuscitation, neuroscience, critical care, trauma, general and neuroanesthesia. His clinical service and research accomplishments have been recognized by many regional, national and international awards. He is a diplomate of the European Academy of Anaesthesia, Board Certified in Anesthesiology by the American Board of Anesthesia, and has a subspecialty certificate in Neurocritical Care from the United Council for Neurologic Subspecialties, American Board of Neurology.
Description of Research
The outcome after ischemic or traumatic insults is highly dependent on implementing methods to mitigate secondary injuries. These protective methods may include pharmacological or mechanical techniques to improve tissue blood flow, as well as tools to mitigate the cascade of events known as the reperfusion injury. Our previous studies focused on the systemic and cerebrovascular effects of different pressors administered during cardiopulmonary resuscitation, as well as the effects of intra-arrest and early post arrest hypothermia. The effects of superimposed trauma were also studied in a model of prolonged cardiac arrest, as well as the feasibility of emergency resuscitation for delayed resuscitation in a model of exsanguination cardiac arrest (also known as suspended animation). An area of recent interest is the effects of microinfarction on cerebral blood flow and electrophysiology, a phenomenon of particular interest in patients with migrainous infarctions or those with perioperative stroke Our goal is to maintain a program to advance methods of enhancing tissue perfusion and mitigating organ damage in patients with severe injury, or those undergoing major surgical procedures.
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