Physician Photo

Jianren Mao, MD, PhD

Chief, Division of Pain Medicine

Vice Chair for Research

Director, MGH Center for Translational Pain Research

  • Phone: 617-726-8810
Department of Anesthesia, Critical Care and Pain Medicine
Clinical Interests
Pain management
Boston: Massachusetts General Hospital
Medical Education
PhD, Medical College of Virginia
MD, Suzhou Medical College
Residency, Medical College Virginia Hospitals
Fellowship, Massachusetts General Hospital
Fellowship, Suzhou Medical College
Board Certifications
Anesthesiology, American Board of Anesthesiology
Pain Medicine, American Board of Anesthesiology
Foreign Languages
Patient Age Group
Accepting New Patients
Accepting New Patients

BiographyThe Mass General Center for Translational Pain Research is devoted to translational research on pain mechanisms and pain treatment. The Center is interested in technology transfer and intellectual property development in pain management.

In the clinical area, we are interested in studying the clinical neurobiology of neuropathic and inflammatory pain and exploring novel pharmacological and interventional approaches for the management of various clinical pain conditions. We have been extensively involved in studying the cellular mechanisms and clinical features of opioid-induced pain, opioid tolerance and addiction.

In the preclinical area, we are interested in studying:

  • the neural and molecular mechanisms of neuropathic pain, opioid tolerance, and opioid-induced hyperalgesia;
  • the role of endogenous cannabinoids in the modulation of neuropathic pain;
  • the role of central glucocorticoid receptors in the neural and molecular mechanisms of pain and opioid tolerance;
  • peripheral and central mechanisms of burn-induced pain and low back pain.

ResearchDr. Mao is the Vice Chair for Research and Chief of Division of Pain Medicine at the MGH Department of Anesthesia, Critical Care and Pain Medicine.  He is also the Director of the MGH Center for Translational Pain Research.  Dr. Mao is the Richard J. Kitz Professor of Anesthesia Research, Harvard Medical School.  His research interests are related to the mechanisms, diagnosis, and treatment of cancer-related pain, neuropathic pain, back and neck pain as well as opioid tolerance, dependence, and addiction.  Dr. Mao's research projects have been well funded by the National Institutes of Health and other sources.

Link to the MGH Center for Translational Pain Research:

PublicationsView publications

Center for Pain Medicine
15 Parkman Street
Boston, MA 02114-3117

Phone: 617-726-8810
Fax: 617-726-3441