Over 40 years, the Institute’s researchers have conducted studies that analyze and validate the effectiveness of mind body medicine.
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Galvin JA, Benson H, Deckro GR, Fricchione GL, Dusek JA. (2006). "The relaxation response: reducing stress and improving cognition in healthy aging adults." Complement Ther Clin Pract 12(3): 186-91.
http://www.ncbi.nlm.nih.gov/pubmed/16835029
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Day, RC and Sadek, SN(1982). "The effect of Benson's relaxation response on the anxiety levels of Lebanese children under stress." J Exp Child Psychol 34(2):350-6.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=6754849
Benson, H, Frankel, FH et al. (1978). "Treatment of anxiety: a comparison of the usefulness of self-hypnosis and a meditational relaxation technique. An overview." Psychother Psychosom 30(3-4):.229-42
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd= Retrieve&db=PubMed&dopt=Citation&list_uids=368852
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Dusek JA, Chang BH, Zaki J, Lazar S, Deykin A, Stefano GB, Wohlhueter AL, Hibberd PL, Benson H. (2006). "Association between oxygen consumption and nitric oxide production during the relaxation response." Med Sci Monit 12(1): CR1-10.
http://www.ncbi.nlm.nih.gov/pubmed/16369463
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Stefano GB, Fricchione GL, Esch T. (2006). "Relaxation: molecular and physiological significance." Med Sci Monit 12(9): HY21-31.
http://www.ncbi.nlm.nih.gov/pubmed/16940938
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Benson H, Dusek JA, Sherwood JB, Lam P, Bethea CF, Carpenter W, Levitsky S, Hill PC, Clem DW Jr, Jain MK, Drumel D, Kopecky SL, Mueller PS, Marek D, Rollins S, Hibberd PL. (2006). "Study of the Therapeutic Effects of Intercessory Prayer (STEP) in cardiac bypass patients: a multicenter randomized trial of uncertainty and certainty of receiving intercessory prayer." Am Heart J 151(4): 934-42.
http://www.ncbi.nlm.nih.gov/pubmed/16569567
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Peng, C, Henry, I, Mietus, J, Hausdorff, J, Khalsa, G, Benson, H, Goldberger, A. (2004). "Heart rate dynamics during three forms of meditation" Int J Cardiol 95: 19-27.
http://www.ncbi.nlm.nih.gov/pubmed/15159033
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Mittleman, MA, Maclure, M et al. (1995). "Triggering of acute myocardial infarction onset by episodes of anger. Determinants of Myocardial Infarction Onset Study Investigators." Circulation 92(7):1720-5.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=7671353
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Benson, H, Alexander, S et al. (1975). "Decreased premature ventricular contractions through use of the relaxation response in patients with stable ischaemic heart-disease."Lancet 2(7931):380-2.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R etrieve&db=PubMed&dopt=Citation&list_uids=51189
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Dusek JA, Otu HH, Wohlhueter AL, Bhasin M, Zerbini LF, Joseph MG, Benson H, Libermann TA. (2008). "Genomic counter-stress changes induced by the relaxation response." PLoS One 3(7): e2576.
http://www.ncbi.nlm.nih.gov/pubmed/18596974
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Fentress, DW, Masek, BJ et al. (1986). "Biofeedback and relaxation-response training in the treatment of pediatric migraine." Dev Med Child Neurol 28(2):139-46.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=3519327
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Benson, H, Klemchuk, HP et al. (1974). "The usefulness of the relaxation response in the therapy of headache." Headache 14(1):49-52.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=4365021
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Benson, H, Malvea, BP et al. (1973). "Physiologic correlates of meditation and their clinical effects in headache: an ongoing investigation." Headache 13(1):23-4.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=4696143
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Dusek JA, Hibberd PL, Buczynski B, Chang BH, Dusek KC, Johnston JM, Wohlhueter AL, Benson H, Zusman RM. (2008). "Stress management versus lifestyle modification on systolic hypertension and medication elimination: a randomized trial." J Altern Complement Med 14(2): 129-38.
http://www.ncbi.nlm.nih.gov/pubmed/18315510
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Leserman, J, Stuart, E et al. (1989). "Nonpharmacologic intervention for hypertension: Long term follow up." J Cardiopulmonary Rehabil 9:316-24.
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Stuart, EM, Caudill, M et al. (1987). "Nonpharmacologic treatment of hypertension: a multiple-risk-factor approach." J Cardiovasc Nurs 1(4):1-14.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=3648099
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Shapiro, AP, Benson, H et al. (1979). "The role of stress in hypertension." J Human Stress 5(2):7-26.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd= Retrieve&db=PubMed&dopt=Citation&list_uids=115914
Benson, H, Kotch, JB et al. (1978). "Stress and hypertension: interrelations and management." Cardiovasc Clin 9(1):113-24.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd= Retrieve&db=PubMed&dopt=Citation&list_uids=352515
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Benson, H(1977). "Can hypertension be induced by stress? A case discussion." J Human Stress 3(1):4-11.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R etrieve&db=PubMed&dopt=Citation&list_uids=15029
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Benson, H, Rosner, BA et al. (1974). "Decreased blood pressure in borderline hypertensive subjects who practiced meditation." J Chronic Dis 27(3):163-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=4830843
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Benson, H, Rosner, BA et al. (1974). "Decreased blood-pressure in pharmacologically treated hypertensive patients who regularly elicited the relaxation response." Lancet 1(7852):289-91.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=4130474
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Keefer, L and Blanchard, EB (2002). "A one year follow-up of relaxation response meditation as a treatment for irritable bowel syndrome." Behav Res Ther 40(5):541-6.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=12038646
Keefer, L and Blanchard, EB (2001). "The effects of relaxation response meditation on the symptoms of irritable bowel syndrome: results of a controlled treatment study." Behav Res Ther 39(7):801-11.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=11419611
Domar, AD, Clapp, D et al. (2000). "Impact of group psychological interventions on pregnancy rates in infertile women." Fertil Steril 73(4):805-11.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=10731544
Domar, AD, Clapp, D et al. (2000). "The impact of group psychological interventions on distress in infertile women." Health Psychol 19(6):568-75.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=11129360
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Domar, AD, Zuttermeister, PC et al. (1993). "The psychological impact of infertility: a comparison with patients with other medical conditions." J Psychosom Obstet Gynaecol 14 Suppl:45-52.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=8142988
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Domar, AD, Broome, A et al. (1992). "The prevalence and predictability of depression in infertile women." Fertil Steril 58(6):1158-63.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=1459266
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Domar, AD, Zuttermeister, PC et al. (1992). "Psychological improvement in infertile women after behavioral treatment: a replication." Fertil Steril 58(1):144-7.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=1623995
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Domar, AD, Seibel, MM et al. (1990). "The mind/body program for infertility: a new behavioral treatment approach for women with infertility." Fertil Steril 53(2):246-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=2078200
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Jacobs, GD, Benson, H et al. (1996). "Perceived benefits in a behavioral-medicine insomnia program: a clinical report." Am J Med 100(2):212-6.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=8629657
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Jacobs, GD, H., B et al. (1993). "Home-based central nervous system assessment of multifactor behavioral intervention for chronic sleep-onset insomnia." Behav Ther 24:159-74.
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Jacobs, GD, Rosenberg, PA et al. (1993). "Multifactor behavioral treatment of chronic sleep-onset insomnia using stimulus control and the relaxation response. A preliminary study." Behav Modif 17(4):498-509.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=8216184
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Conboy, L, Domar, A et al. (2001). "Women at mid-life: symptoms, attitudes, and choices, an internet based survey." Maturitas 38(2):129-36.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=11306201
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Samuelson M, Foret M, Baim M, Lerner J, Fricchione G, Benson H, Dusek J, Yeung A (2010). "Exploring the effectiveness of a comprehensive mind-body intervention for medical symptom relief." J Altern Complement Med 16(2): 187-92.
http://www.ncbi.nlm.nih.gov/pubmed/20180692
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Nakao, M, Fricchione, G et al. (2001). "Anxiety is a good indicator for somatic symptom reduction through behavioral medicine intervention in a mind/body medicine clinic." Psychother Psychosom 70(1):50-7.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=11150939
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Nakao, M, Myers, P et al. (2001). "Somatization and symptom reduction through a behavioral medicine intervention in a mind/body medicine clinic." Behav Med 26(4):169-76.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=11409219
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Lazar SW, Kerr CE, Wasserman RH, Gray JR, Greve DN, Treadway MT, McGarvey M, Quinn BT, Dusek JA, Benson H, Rauch SL, Moore CI, Fischl B. (2005). "Meditation experience is associated with increased cortical thickness." Med Sci Monit 9(2): RA23-34.
http://www.ncbi.nlm.nih.gov/pubmed/16272874
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Lazar SW, Bush G, Gollub RL, Fricchione GL, Khalsa G, Benson H. (2000). "Functional brain mapping of the relaxation response and meditation." Neuroreport 11(7): 1581-5.
http://www.ncbi.nlm.nih.gov/pubmed/10841380
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Beard C, Stason WB, Wang Q, Manola J, Dean-Clower E, Dusek JA, Decristofaro S, Webster A, Doherty-Gilman AM, Rosenthal DS, Benson H (2010). "Effects of complementary therapies on clinical outcomes in patients being treated with radiation therapy for prostate cancer." Cancer. 2010 Aug 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/20803609
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Schaffer, SD and Yucha, CB(2004). "Relaxation & pain management: the relaxation response can play a role in managing chronic and acute pain." Am J Nurs 104(8):75-6, 78-9, 81-2.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=15300063
Caudill, M, Schnable, R et al. (1991). "Decreased clinic use by chronic pain patients: response to behavioral medicine intervention." Clin J Pain 7(4):305-10.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=1809444
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Kutz, I, Caudill, M et al. (1983). "The role of relaxation in behavioral therapies for chronic pain." Int Anesthesiol Clin 21(4):193-200.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=6642701
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Goodale, IL, Domar, AD et al. (1990). "Alleviation of premenstrual syndrome symptoms with the relaxation response." Obstet Gynecol 75(4):649-55.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=2179779
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Esch, T, Guarna, M, Bianchi, E, Zhu, W, Stefano, G. (2004). "Commonalities in the central nervous system’s involvement with complementary medical therapies: limbic morphinergic processes." Med Sci Monit 9(2): RA23-34.
http://www.ncbi.nlm.nih.gov/pubmed/15173679
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Esch, T, Fricchione, GL et al. (2003). "The therapeutic use of the relaxation response in stress-related diseases." Med Sci Monit 9(2):RA23-34.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=12601303
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Esch, T, Stefano, GB et al. (2002). "The role of stress in neurodegenerative diseases and mental disorders." Neuro Endocrinol Lett 23(3):199-208.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=12080279
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Esch, T, Stefano, GB et al. (2002). "Stress-related diseases -- a potential role for nitric oxide." Med Sci Monit 8(6):RA103-18.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=12070451
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Esch, T, Stefano, GB et al. (2002). "Stress in cardiovascular diseases." Med Sci Monit 8(5):RA93-RA101.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list_uids=12011786
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Mandle, CL, Jacobs, SC et al. (1996). "The efficacy of relaxation response interventions with adult patients: a review of the literature." J Cardiovasc Nurs 10(3):4-26.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=8820317
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Vitalo A, Fricchione J, Casali M, Berdichevsky Y, Hoge EA, Rauch SL, Berthiaume F, Yarmush ML, Benson H, Fricchione GL, Levine JB. (2009). "Nest making and oxytocin comparably promote wound healing in isolation reared rats." PLoS One 4(5): e5523.
http://www.ncbi.nlm.nih.gov/pubmed/19436750
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Mandle, CL, Domar, AD et al. (1990). "Relaxation response in femoral angiography." Radiology 174(3 Pt 1):737-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=2406782
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Leserman, J, Stuart, EM et al. (1989). "The efficacy of the relaxation response in preparing for cardiac surgery." Behav Med 15(3):111-7.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=2676027
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Domar, AD, Noe, JM et al. (1987). "The preoperative use of the relaxation response with ambulatory surgery patients." J Human Stress 13(3):101-7.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=3309050
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Deckro, JP, Domar, AD et al. (1993). "Clinical application of the relaxation response in women's health. AWHONNS" Clin Issues Perinat Womens Health Nurs 4(2):311-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd =Retrieve&db=PubMed&dopt=Citation&list_uids=8242053
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