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Sumner M. Redstone Burn Center
Some virtuosos play the piano to perfection, others paint like Picasso, but for MGH physician-researchers, talent lies in the art of discovery.
Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns.
Serious traumatic injuries, including major burns, set off a "genomic storm" in human immune cells, altering around 80 percent of the cells' normal gene expression patterns.
A team led by MGH scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils – the most abundant type of white blood cell – from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury.
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