Massachusetts General Hospital | Cancer Center

02/03/2012: Dyson appointed scientific director

Nick Dyson, PhD, has been appointed scientific director of the MGH Cancer Center.

01/31/2012: Mass. General study defines a new genetic subtype of lung cancer

MGH Cancer Center investigators have defined the role of a recently identified gene abnormality – rearrangements in the ROS1 gene – in non-small-cell lung cancer, the leading cause of cancer death in the U.S. They also show that these tumors can be treated with crizotinib and describe the remarkable response of one patient to such treatment.

01/18/2012: Novel gene mutations associated with bile duct cancer

Investigators at the MGH Cancer Center have identified a new genetic signature associated with bile duct cancer, a usually deadly tumor for which effective treatment currently is limited.

01/16/2012: Combining two anti-HER2 drugs may provide better preoperative breast cancer treatment

Using two drugs that inhibit the growth factor HER2 for preoperative treatment of early-stage HER2-positive breast cancer appears to have better results than treatment with a single agent.

12/16/2011: Mass General-led Breast Cancer Studies Received early New England Journal of Medicine Publication

Two New England Journal of Medicine papers reporting the results of separate Phase III clinical trials for the treatment of advanced breast cancer recently received early, online first release because the studies were presented at the December 2011 CTRC-AACR San Antonio Breast Cancer Symposium.

12/01/2011: Mass. General study finds amplification of multiple cell-growth genes in some brain tumors

A small percentage of the deadly brain tumors called glioblastomas, which usually resist treatment with drugs targeting mutations in cell-growth genes, appears to contain extra copies of two or three of these genes at the same time. The surprising discovery has major implications for the understanding of tumor biology and for targeted cancer therapies.

11/18/2011: Patriots touch down at MGH

New England Patriots Nate Solder and Brandon Deaderick – as well as former Patriot Thomas Welch, who signed with the Buffalo Bills Nov. 17 – made a surprise visit Nov. 8 to patients at MassGeneral Hospital for Children and the MGH Cancer Center’s Infusion Unit.

11/15/2011: Denosumab delays development of prostate cancer bone metastasis

An international clinical trial has found that treatment with a drug that suppresses the normal breakdown of bone can delay the development of bone metastases in men with prostate cancer.

11/13/2011: Newly identified gene mutation adds to melanoma risk

A major international study has identified a novel gene mutation that appears to increase the risk of both inherited and sporadic cases of malignant melanoma, the most deadly form of skin cancer. The identified mutation occurs in the gene encoding MITF, a transcription factor that induces the production of several important proteins in melanocytes, the cells in which melanoma originates.

10/28/2011: From the Tumor Clinic to the Termeer Center

The MGH Tumor Clinic – the first clinic of its kind at a general hospital – was established in 1925 and led by George W. Holmes, MD, chief of the X-ray Department, who brought together staff from various disciplines to discuss cancer cases in which radiation had proved effective when the traditional treatment of surgery had failed.

10/21/2011: ‘This is my thank you’

Fifteen-year-old Mike Duffy III came to the MGH on Oct. 13 to say thank you to the physicians who saved his father’s life.

10/03/2011: Ovarian Cancer Survivors Course

A recap of the Ovarian Cancer Survivors Course

10/03/2011: Staff Snapshot

Kathleen Gill-Bazazi: Manager/Buyer for Images Oncology Boutique North Shore and Boston; Manager of The General Hair Care in Boston.

09/28/2011: New Hope for Cancer Patients

For a number of years the Mass General Cancer Center has been at the forefront of the promising field of targeted therapy, in which treatment is tailored to attack specific genetic mutations responsible for an individual patient’s tumor. A major gift of $10 million from Henri and Belinda Termeer, announced Sept. 13, will enable the Cancer Center to expand its efforts in this area through the creation of the Henri and Belinda Termeer Center for Targeted Therapies.

09/26/2011: Overcoming Drug Resistance to Targeted Cancer Therapies

A concerted effort is under way at the Mass General Cancer Center to understand why and how cancer cells become resistant to targeted therapies. (From Advances Fall 2011 issue.)

09/13/2011: News about the Henri and Belinda Termeer Center for Targeted Therapies

Read the latest news coverage about the Henri and Belinda Termeer Center for Targeted Therapies

08/11/2011: Mass General Imaging introduces CT lung-cancer screening

Research shows a clear benefit for CT lung-cancer screening among individuals who meet strict criteria. Patients and referrers should understand both the benefit and the potential for false positive results.

07/19/2011: MGH ranks #2 in nation

MGH ranks #2 in 2011-2012 U.S. News & World Report "Best Hospitals" rankings

07/13/2011: Large clinical trial shows short-term hormone therapy plus radiation increases survival for men with early-stage prostate cancer

Short-term hormone therapy given in combination with radiation therapy for men with early-stage prostate cancer increases their chance of living longer and not dying from the disease, compared with patients who receive the same radiation therapy alone.

07/01/2011: The Wonder of Lunder

An update on Mass General’s new Lunder Building, and what it will mean for the Cancer Center

07/01/2011: Healthy Grilling

From barbecue season through tailgating time, grilling is more of a lifestyle than a method of cooking food. It can be a delicious part of healthy living if you follow these tips to maximize flavor while minimizing your cancer risk.

07/01/2011: Connections

Lisa Marie Doyle, RN, Staff Nurse, Gynecology Oncology, Bigelow 7

07/01/2011: Breakthroughs from ASCO

Cancer Center investigators and physician-scientists share promising research and treatment developments in breast cancer, melanoma and more.

07/01/2011: A Powerful Partnership

The Mass General Cancer Center teams up with the American Cancer Society to increase education, awareness and funding to fight cancer.

06/10/2011: Cancer Center celebrates the one hundred

MGH Hotline 6.10.11 One individual can make an incredible difference for a patient with cancer.

06/10/2011: MGH launches new award to support research

MGH Hotline 6.10.11 Selected from among 115 applications from across the MGH research community, the inaugural MGH Research Scholars recently were announced at the annual meeting of the MGH Research Advisory Council (RAC).

06/02/2011: Healthy Picks

June marks the start of the best time of year to find the widest variety of delicious, nutritious fruits and vegetables in New England. If you’re looking for the healthiest produce for the best prices, or wondering what terms like “organic”, “local” and “natural” really mean to you, here’s a quick guide to making the best summer selections.

06/02/2011: Summer of Support

As warmer weather approaches, the Cancer Center community looks forward to a summer filled with informational and inspirational events. There’s something for everyone, so get involved!

06/02/2011: Target: Melanoma

The latest news on melanoma treatment and research from the new issue of Synergy magazine and a recent edition of the television program Chronicle.

06/02/2011: Staff Snapshot

David Apostol, Senior Project Specialist

05/20/2011: MGH Cancer Center awards research prize

The MGH Cancer Center presented its annual MGH Award in Cancer Research on April 8 to Michael R. Stratton, MD, PhD, director of the Wellcome Trust Sanger Institute.

05/02/2011: Carlos Fernandez-Robles, MD, honored as part of the one hundred

Since joining the Bone Marrow Transplant Service at Mass General in 2009, Psychiatric Oncologist Carlos Fernandez-Robles, MD, has dramatically expanded its inpatient psychiatric consultation services.

05/02/2011: Fredrica Preston, NP, honored as part of the one hundred

From 1995 to 2010, Fredrica (Ricky) Preston, RNC, NP, AOCN, was the sole nurse practitioner in medical oncology at the Mass General/North Shore Cancer in Danvers, Mass. With great commitment, compassion and knowledge, she quickly established an advanced practice that enables North Shore residents to access exemplary cancer care without traveling to Boston.

05/02/2011: Shedding Light on Sun Protection

It’s important to remember that May’s longer days and more intense sun can also leave us vulnerable to skin damage as we enjoy outdoor activities. Protect yourself by following these simple tips.

04/28/2011: Nicholas Dyson, PhD, honored as part of the one hundred

Dr. Dyson, a senior scientist at the Center for Cancer Research, has made breakthroughs in our understanding of the way cells divide, whether it is the regulated division of a normal cell or the abnormal proliferation of a malignant cancer.

04/22/2011: MGHfC patient first to join hospital marathon team

On Marathon Monday, April 18, one MassGeneral Hospital for Children (MGHfC) patient reached another milestone in her recovery from cancer

04/22/2011: Celebrating prize-winning MGH research

The presentation of the MGH's top research prizes was a highlight of the April 13 Celebration of Science, held in conjunction with the annual Scientific Advisory Committee meeting.

04/22/2011: SAC meeting

The 64th meeting of the MGH Scientific Advisory Committee (SAC) on April 14 celebrated key accomplishments of MGH investigators, past and present, and examined strategies for meeting the challenges currently facing the academic biomedical research community.

04/08/2011: SAC meeting to honor past scientific leadership, address current challenges

ALL MGHERS are invited to attend the 2011 meeting of the MGH Scientific Advisory Committee (SAC), which will commemorate the hospital’s bicentennial with a look back at significant research accomplishments of MGH investigators and examine challenges facing today’s research community.

04/05/2011: Clinical Conversations

Being an empowered patient sometimes means asking the tough questions. Esophageal cancer survivor, Fritz Ferbert, is so glad he did.

04/04/2011: Stand Up To Cancer

Sridhar Ramaswamy, MD, awarded a Research Innovation Grant to fund his lab’s work on the mechanisms of cancer cell survival, metastasis, drug resistance, and dormancy.

03/23/2011: Mass. General study reveals how lung cancers evolve in response to targeted treatment

A detailed analysis of lung tumors that became resistant to targeted therapy drugs has revealed two previously unreported resistance mechanisms. The report also describes how the cellular nature of some tumors can change in response to treatment and finds how resistance-conferring mutations can disappear after treatment is discontinued.

03/23/2011: Epigenomic findings illuminate veiled variants

Genes make up only a tiny percentage of the human genome, but the rest may hold vital clues about the genetic origins of disease. Using a new mapping strategy, a research team has begun to assign meaning to the regions beyond our genes and has revealed how minute changes in these regions might be connected to common diseases.

03/18/2011: Lunder Building 9 and 10 medical oncology floors

MGH Hotline 3.18.11

03/09/2011: Aspirin's ability to protect against colorectal cancer may depend on risk-associated inflammatory pathways

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs may be limited to individuals already at risk because of elevations in a specific inflammatory factor in the blood.

03/01/2011: Breaking Barriers

The Colorectal Cancer Screening Navigator Program at Mass General Chelsea Healthcare Center is reducing disparities in screening rates among minority patients.

03/01/2011: Staff Snapshot

Oncology Nutritionist, Julia Hincman-Francavilla, MS, RD, LDN

02/18/2011: A lifesaving gift

MGH Hotline 2.18.11 The meeting of 50-year-old Erin Cortright with 28-year-old Carrie Atkins, surrounded by a team of MGH caregivers from the Bone Marrow Transplant Unit, brought tears to many eyes.

02/14/2011: Genetic Profiling Uncovers New Therapeutic Approaches to Ovarian Cancer

Advances Spring 2011 Issue. In the United States, ovarian cancer remains the deadliest of all gynecologic malignancies and the fifth leading cause of cancer death for women. The lack of an adequate early-detection screening assay is a major factor in the high fatality rate. More than 75 percent of cases present with advanced-stage disease; of these patients, fewer than 30 percent have five-year disease-free survival rates or are cured.

02/04/2011: MGH and CBS care

MGH Hotline 02.04.11 To promote awareness about the disease and the importance of self-exams, the MGH and CBS Cares are collaborating on a fun, informative public service announcement (PSA).

02/01/2011: von Hippel-Lindau Disease

December and January episodes of the television show “Grey’s Anatomy” featured a storyline about von Hippel-Lindau (VHL) disease, a rare but serious genetically-inherited condition that can cause abnormal blood vessel growth and tumor development. Gayun Chan-Smutko, MS, CGC, a genetic counselor in the Cancer Center’s von Hippel-Lindau Clinic discusses testing, screening and treatment options for VHL.

02/01/2011: A look to the future of personalized medicine

Cancer Center Associate Director and Chief of Hematology/Oncology José Baselga, MD, PhD, continues our quest to bring the most promising targeted therapies from the bench to the bedside.

02/01/2011: Staff Snapshot

Senior Genetic Counselor, Gayun Chan-Smutko, MS, CGC

02/01/2011: Pitch Perfect

TargetCancer raises awareness of rare cancers –and funds for targeted therapy research – with an ensemble of music-related efforts.

02/01/2011: Conversations from the Heart

Elizabeth Davis, MD, is a psychiatric oncologist in the Cancer Center’s Survivorship Program. She helps patients cope with both the emotional and physical side effects of cancer. Here, Dr. Davis shares tips for couples facing cancer together.

01/13/2011: Overexpression of repetitive DNA sequences discovered in common tumor cells

MGH Cancer Center researchers have discovered a previously unknown feature of common tumor cells – massive overexpression of satellite repeats, which are DNA sequences that do not code for proteins. The findings may improve understanding of tumor development and provide a new cancer biomarker.

01/11/2011: Small steps, big benefits in 2011

Whatever your goal in 2011, diet and exercise can certainly help reduce side effects of cancer treatment, improve your mood and increase overall health.

01/11/2011: Staff Snapshot

Radiation Oncology Nurse, Maryellen Lewis, RN, BSN, OCN

01/11/2011: Ringing in the New Year

Patients in Mass General Cancer Center's Francis H. Burr Proton Therapy Center ring a bell to mark the end of treatment.

01/11/2011: Paying it Forward

After nearly losing everything to stage-4 ovarian cancer, Kim Lohnes is helping others receive the care they desperately need.

01/03/2011: Mass. General Hospital enters collaboration to develop new approach to capturing circulating tumor cells

MGH has entered into a collaborative agreement with Veridex LLC to establish a center of excellence in research on circulating tumor cell technologies.

12/17/2010: Hall of Fame visit to MGH Cancer Center

MGH Hotline 12.17.10 He's considered one of the best linemen ever to play professional football, and on Dec. 2, former New England Patriots player and National Football League Hall of Fame member John Hannah helped brighten the day of patients and employees at the MGH Cancer Center when he stopped by for a visit.

12/17/2010: Handmade pillowcases bring holiday cheer

MGH Hotline 12.17.10 While having visions of sugarplum fairies, MassGeneral Hospital for Children (MGHfC) patients will be resting their heads on colorful handmade pillowcases they helped sew on Dec. 11 in the Ellison 18 Playroom with volunteers Marie Nader and Jane Cunniffe of ConKerr Cancer: A Case for Smiles.

12/14/2010: New targeted lung cancer drug produces 'dramatic' symptom improvement

A clinical trial of a potential new targeted treatment drug has provided powerful evidence that it can halt or reverse the growth of lung tumors characterized by alterations in the anaplastic lymphoma kinase (ALK) gene.

12/13/2010: Cancer Genome Research: An Update

Massachusetts General Hospital Cancer Center and the Wellcome Trust Sanger Institute's alliance in cancer genome research aims to provide novel insights into genetic features of individual tumors that may determine their response to drug treatment.

12/13/2010: Coping with Cancer at the Holidays

Tips for managing holiday stress from Liz Davis, MD, of the Cancer Center Survivorship Program

12/13/2010: Staff Snapshot

After nearly three decades with the Cancer Center, Pediatric Oncology Social Worker, Ev Malkin, LICSW is retiring this January.

12/13/2010: Cancer Center teams with the Patriots

Cancer Center teams with the Patriots for Monday Night Football awareness night as part of the season-long "Kick Cancer" initiative.

12/10/2010: Supporting brain cancer research

MGH Hotline 12.10.10 When her father John was diagnosed with a glioblastoma in June 2009, 10-year-old Elana Sargent wanted to find a way to help.

12/10/2010: Baselga first incumbent of Chabner Chair in Hematology Oncology

MGH Hotline 12.10.10 A named chair is one of the highest honors a physician may receive in his or her lifetime.

12/02/2010: Patriots and Mass General Hospital to raise awareness for colorectal cancer at Monday night's game

As part of the New England Patriots Charitable Foundation's season-long "Kick Cancer" initiative, and in partnership with Mass General Hospital, the Patriots will promote colorectal cancer awareness at the December 6 Monday night matchup at Gillette Stadium versus the New York Jets.

12/01/2010: Tumors bring their own support cells when forming metastases

A new study from MGH Cancer Center researchers finds that circulating tumor cells bring along from the original tumor site noncancerous cells that facilitate the development of metastases.

11/12/2010: Iditarod champion shares cancer story

MGH Hotline 11.12.10 Although oct. 22 was a typical autumn day with temperatures in the 60s, patients and staff were magically transported to the frozen Alaskan tundra when four-time Iditarod Trail Dog Sled Race winner Lance Mackey paid a visit to the MGH Cancer Center.

11/10/2010: Romiplostim more effective than standard care for immune thrombocytopenia

A new study finds that an FDA-approved drug to treat the rare autoimmune disorder immune thromobocytopenia (ITP) is more effective than earlier medical therapies in helping patients avoid surgical treatment and significantly improving their quality of life.

11/05/2010: Spooktacular celebrations

MGH Hotline 11.05.10 Fairies, princesses and pirates could be seen throughout campus last week as pediatric patients participated in several Halloween events hosted by MassGeneral Hospital for Children (MGHfC) and several charities.

11/01/2010: A delicate balance

Cancer Center oncology nutritionists and guest bloggers, Julia Hincman-Francavilla and Carol Sullivan, provide helpful tips for patients living with and beyond cancer.

11/01/2010: No stomach for cancer

This November, a Cancer Center patient and her organization “No Stomach for Cancer” are leading the celebration of the first National Stomach Cancer Awareness Month.

11/01/2010: Staff Snapshot

Stefanie Ryan joined the Cancer Center in 2006 as an expressive arts therapy intern from Lesley University.

11/01/2010: Researchers hone in on treatment targets for ovarian cancer

Gynecologic cancer research Program Director Michael Birrer, MD, PhD, explains how ovarian tumor discoveries in the lab are already impacting patient care.

10/27/2010: New targeted lung cancer drug produces 'dramatic' symptom improvement

A clinical trial of a potential new targeted treatment drug has provided powerful evidence that it can halt or reverse the growth of lung tumors characterized by alterations in the anaplastic lymphoma kinase (ALK) gene.

10/15/2010: A special "kick" at MGHfC

MGH Hotline 10.15.10 Despite recent changes in the New England Patriots lineup, MassGeneral Hospital for Children (MGHfC) patients remain faithful fans.

10/12/2010: Second-generation device more effective in capturing circulating tumor cells

A redesigned version of the CTC-Chip – a microchip-based device for capturing rare circulating tumor cells (CTCs) – appears to be more effective and should be easier to manufacture than the original. Called the HB-(herringbone) Chip, the new device also may provide more comprehensive and easily accessible data from captured tumor cells.

10/08/2010: Aladdin's Adventure

MGH Hotline 10.08.10 More than 400 friends and supporters of MassGeneral Hospital for Children (MGHfC) enjoyed the magical storybook theme of Aladdin's Arabian nights at the 11th annual Storybook Ball at The Castle at Park Plaza.

10/01/2010: MGH teams up with Patriots to help Kick Cancer

MGH Hotline 10.01.10 Nearly 70,000 fans pack the stands at Gillette Stadium for every New England Patriots home game, and statistically, more than one third will develop cancer in their lifetimes.

09/27/2010: The Patriots Aim to Kick Cancer

Nearly 70,000 fans pack the stands at Gillette Stadium for every Patriots home game and, statistically, far too many of them will develop cancer in their lifetimes. With support from Brigham and Women’s Hospital, Massachusetts General Hospital – the founding hospitals of Partners HealthCare – and Dana-Farber Cancer Institute, the New England Patriots Charitable Foundation has launched Kick Cancer, a season-long initiative to increase cancer awareness among Patriots fans.

09/24/2010: Stand Up to Cancer

MGH Hotline 9.24.10 The Liberty Hotel ballroom filled quickly on the evening of Sept. 10 as the MGH Development Office hosted a viewing of the Stand Up to Cancer television broadcast.

08/27/2010: Cops for Kids with Cancer

MGH Hotline 08.27.10 During what's become a summertime tradition, several pediatric cancer patients, along with their siblings and parents enjoyed an evening filled with exciting activities designed to give them a break from the stresses of cancer treatment.

08/27/2010: Palliative care

MGH Hotline 08.27.10 Integrating palliative care early in the treatment of advanced lung cancer not only improved patients' mood and quality of life, but also extended their lives.

08/25/2010: Targeted drug leads to rapid regression of metastatic melanoma in patients with mutated BRAF gene

Use of an experimental targeted drug to treat metastatic melanoma tumors with a specific genetic signature was successful in more than 80 percent of patients in a phase 1 clinical trial.

08/18/2010: Lung cancer patients receiving palliative care had improved quality of life, extended survival

Integrating palliative care early in the treatment of patients with advanced lung cancer not only improved their mood and quality of life, it also extended their lives.

08/06/2010: A special bond

MGH Hotline 08.06.10 This summer, one MGH physician traded his white coat for a suit jacket and his stethoscope for a wedding ceremony script when he officiated the wedding of one of his longtime patients.

08/04/2010: MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment

MGH investigators have identified a new mechanism that controls the number of the stem cells that give rise to all blood and immune system cells, an advance that may improve treatment of blood system cancers.

07/23/2010: MGHfC honors amazing mothers

MGH Hotline 7.23.10 CANCER DOESN'T just affect the people diagnosed with it -- it affects entire families.

07/15/2010: Largest study of genomes and cancer treatments releases first results

The largest study to correlate genetics with response to cancer drugs releases its first results today. The researchers behind the study, based at the MGH Cancer Center and the Wellcome Trust Sanger Institute, describe the responses of 350 cancer samples to 18 anticancer therapeutics.

06/25/2010: Celebrating the one hundred

MGH Hotline 06.25.10 MORE THAN 650 guests attended the MGH Cancer Center’s annual fundraiser, the one hundred, held June 2 at the Westin Boston Waterfront.

06/18/2010: Cancer Center recognizes employees of the year

MGH Hotline 06.18.10 The MGH Cancer Center recognized not one but two individuals during this year’s employee of the year celebration.

06/18/2010: 2010 Claflin awards support six women researchers

MGH Hotline 06.18.10 Named for Jane D. Claflin, an honorary trustee who has championed women in academic medicine at the MGH, the Claflin Distinguished Scholar Awards are presented each year to outstanding women researchers who have the dual responsibility of caring for children.

06/15/2010: Combined BRAF-targeted and immunotherapy shows promise for melanoma treatment

Combined targeted therapy against the BRAF/MAPK pathway with immunotherapy shows promise as a new therapeutic approach for the treatment of melanoma, according to results of a preclinical study by MGH researchers.

06/03/2010: Study finds epigenetic similarities between Wilms tumor cells and normal kidney stem cells

A detailed analysis of the epigenetics – factors controlling when and where genes are expressed – of Wilms tumor reveals striking similarities to stem cells normally found in fetal kidneys. These findings by MGH Cancer Center researchers reveal new cellular pathways critical for Wilms tumor development that may apply to other pediatric cancers.

05/17/2010: Treatment reverses hearing loss in patients with neurofibromatosis type 2

Neurofibromatosis type 2 (NF2) is a genetic condition associated with bilateral vestibular schwannomas. It is rare, affecting only about one in 25,000 people.

05/15/2010: Avon Walk Boston supports research and care at Mass General

As part of the Eighth Annual Avon Walk Boston, the Avon Foundation awarded a generous research and patient care grant to Mass General's breast cancer program.

05/07/2010: In General awards and honors

MGH Hotline 5.07.10 In General awards and honors

05/04/2010: Sridhar Ramaswamy, MD, elected to the American Society of Clinical Investigation (ASCI)

The ASCI is an honor society of physician-scientists, who translate findings in the laboratory to the advancement of clinical practice.

04/18/2010: A Multidisciplinary Approach to Cancer Detection and Treatment: What’s On the Horizon

Cancer is a multifaceted disease that requires multiple approaches to diagnosis and management. At the American Association for Cancer Research 101st Annual Meeting 2010, scientists and clinicians will present more than 6,300 abstracts dealing with innovative aspects of biology, technology and emerging therapies.

04/16/2010: CUTS FOR A CAUSE

MGH Hotline 4.16.10 FOR THE THIRD YEAR IN A ROW, Boston Bruins players stepped into the "hot seat" -- or in this case, barber shop chairs -- to raise money for the Pediatric Hematology-Oncology Unit at MassGeneral Hospital for Children (MGHfC).

04/02/2010: Martin Research Award honorees

MGH Hotline 4.2.10 STUDIES REVEALING NETWORKS underlying key aspects of the immune system and describing a novel application of an antiangiogenesis drug were recognized with the second annual Joseph B. Martin Research Awards at the Feb. 24 Celebration of Science, held in conjunction with the Scientific Advisory Committee meeting.

04/01/2010: Treatment resistance in some cancer cells may be reversible

The ability of cancer cells to resist treatment with either targeted drug therapies or traditional chemotherapy may, in some cases, result from a transient state of reversible drug "tolerance."

03/31/2010: Improved device provides more rapid, comprehensive analysis of circulating tumor cells

Technical improvements to a microchip-based device for detecting and analyzing tumor cells in the bloodstream are revealing cellular differences that may reflect a tumor's aggressiveness and long-term response to treatment.

03/31/2010: Colorectal Screening Saves Lives

Colorectal cancer is the third leading cause of cancer death among men and women nationwide. But, if detected early colorectal cancer is treatable and beatable.

03/23/2010: A young mother battles a rare cancer

Sarcomas are malignant tumors that develop in muscle, bone, fat and other connective tissue in the human body. The Center for Sarcoma and Connective Tissue Oncology at the MGH Cancer Center is one of the few centers in the United States that specializes in the detection and treatment of these rare cancers. The Center is supported in part by the Jennifer Hunter Yates Sarcoma Foundation, which was established in honor of Yates, a patient at Mass General. Since 2005, the Foundation has raised nearly $600,000 and is helping patients from around the country battle this devastating disease.

03/21/2010: "Good" cells can go "bad" in a "bad neighborhood"

A new study by Harvard researchers at Massachusetts General Hospital indicates that “good” cells can become cancerous because of exposure to a “bad” environment within the body — similarly to the way a “good boy” may turn to crime when exposed to the pressures of life in a crime-ridden neighborhood.

03/19/2010: José Baselga, MD, PhD, joins MGH Cancer Center

MGH Hotline 3.19.10 RELOCATING FROM BARCELONA, Spain, to Boston, José Baselga, MD, PhD, chairman of the Medical Oncology Service and director of the Division of Medical Oncology, Hematology and Radiation Oncology at the Vall d'Hebron Institute of Oncology, will join the MGH this summer as chief of the Division of Hematology/Oncology and associate director of the MGH Cancer Center.

03/16/2010: Increased radiation dose does not increase long-term side effects for prostate cancer patients

Boosting the radiation dose given to prostate cancer patients to a level that cut recurrence in half did not increase the severity of side effects reported by patients up to a decade later. Patients also found the impact of continuing side effects on their quality of life to be less bothersome than would be expected, based on earlier studies.

03/11/2010: Possible ovarian cancer treatment target identified

A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer.

02/23/2010: Combined Mammography and Breast MRI Useful for Some High-Risk Women

Annual breast cancer screening with both mammography and magnetic resonance imaging is likely to be a cost-effective way to improve life expectancy in women with an increased risk of breast cancer.

02/01/2010: Radiation Oncology Safety at Mass General

An open letter to the Mass General community in response to national concerns about the safety of radiation delivery technology.

01/21/2010: Lack of cellular enzyme triggers switch in glucose processing

A study investigating how a cellular enzyme affects blood glucose levels in mice provides clues to pathways that may be involved in processes including the regulation of longevity and the proliferation of tumor cells.

01/05/2010: Landmark bone study addresses debilitating side effect of prostate cancer treatment

Vertebral fractures in men receiving androgen-deprivation therapy for prostate cancer are associated with pain, loss of mobility, and decreased survival.

12/18/2009: Cervical Cancer Screening

The American College of Obstetricians and Gynecologists (ACOG) recently released new guidelines for cervical cancer screening. Dr. Marcela Del Carmen from the Obstetrics and Gynecology Service and Dr. Elizabeth Roth from the Women’s Health Associates at Mass General help put this in context.

12/14/2009: Connecting the Dots

A team of researchers led by Daniel Haber, MD, PhD, director of the MGH Cancer Center, recently announced that they have revealed a unique molecular mechanism that might control the growth of cancer cells.

12/08/2009: Possible ovarian cancer treatment target identified

A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer.

09/22/2009: New drug could significantly improve patient quality of life:

Matthew Smith, MD, PhD, of the Massachusetts General Hospital Cancer Center, led a study on a new targeted therapy to stop bone loss, increase bone density and prevent spinal fractures in men receiving androgen-deprivation therapy for prostate cancer.

08/24/2009: Minimally invasive surgery lessens pain of esophageal cancer

Christopher Morse, MD, of the Division of Thoracic Surgery at Massachusetts General Hospital has been able to remove esophageal tumors using an innovative minimally invasive procedure that offers patients less postoperative pain and a shorter recovery time

08/11/2009: Denosumab increases bone density, cuts fracture risk in prostate cancer survivors

Twice-yearly treatment with denosumab, a new targeted therapy to stop bone loss, increased bone density and prevented spinal fractures in men receiving androgen-deprivation therapy for prostate cancer.

07/15/2009: MGH study identifies first molecular steps to childhood leukemia

A Massachusetts General Hospital-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia – the most common cancer in children – initiates the disease process.

07/13/2009: Avoiding the dangers of sun exposure

David Fisher, MD, PhD, chief of Dermatology at Massachusetts General Hospital, offers advice on how to avoid long-term photo damage from sun exposure.

07/08/2009: Antiangiogenesis treatment improves hearing in some NF2 patients

Treatment with the angiogenesis inhibitor bevacizumab improved hearing and alleviated other symptoms in patients with neurofibromatosis type 2 (NF2). The study by researchers from Massachusetts General Hospital (MGH) represents the first report of a successful NF2 treatment not involving surgery or radiation.

06/22/2009: A New Milestone in the Fight Against Cancer

A landmark grant funds groundbreaking cancer research led by the Cancer Center to accelerate CTC-chip research, offering the potential to revolutionize how oncologists detect, monitor and treat cancers in the future.

06/12/2009: Celebrating the one hundred

MGH Hotline 06.12.09 It can be hard to quantify the emotional impact caregivers, researchers, donors, volunteers and advocates have on cancer patients and their families, but in many ways, the MGH Cancer Center’s the one hundred does just that.

06/05/2009: Employees of the year

MGH Hotline 6.5.09 Though in different departments, the winners of the MGH Cancer Center and the Radiation Oncology Department employee of the year awards have one thing in common: an outstanding ability to treat all patients with respect and kindness.

06/01/2009: Hitting where it hurts

A new study uncovers a gene expression signature that reliably identifies cancer cells whose survival is dependent on a common signaling pathway, even when the cells contain multiple other genetic abnormalities. The study from MGH Cancer Center researchers identifies critical molecular vulnerabilities, thereby revealing promising therapeutic targets for a common and notoriously treatment resistant cancer.

05/29/2009: MGH Cancer Center receives $15 million grant from SU2C

MGH Hotline 05.29.09 The MGH Cancer Center has been awarded a $15 million research grant from the proceeds raised by the landmark Sept. 5, 2008 Stand Up to Cancer (SU2C) telethon.

05/29/2009: In General awards and honors

MGH Hotline 05.29.09 In General awards and honors

05/22/2009: Michael Birrer, MD, PHd Elected to GCSC

Michael Birrer, MD, PhD, director of Massaschusetts General Hospital Cancer Center gynecologic medical oncology, has been elected as the new co-chair of the Gynecologic Cancer Steering Committee (GCSC).

05/22/2009: Jennifer Temel, MD Receives Palliative Care Grant Award

Jennifer Temel, MD has been awarded an American Cancer Society Pilot Project Support Grant.

05/22/2009: Avon Walk for Breast Cancer

The seventh annual Avon Walk for Breast Cancer, held in Boston the weekend of May 17, 2009, helped raise $5.6 million to advance access to care and finding a cure for breast cancer.

05/18/2009: Study examines trends in gallbladder cancer over 4 decades

Overall prognosis for gallbladder cancer appears to be improving, although many patients still have incurable disease and poor survival rates.

05/15/2009: Bernstein and Hochedlinger among 50 HHMI Early Career Scientists

MGH Hotline 5.15.09 Two MGH scientists — Bradley Bernstein, MD, PhD, of the Department of Pathology, and Konrad Hochedlinger, PhD, of the Center for Regenerative Medicine – are among the first group of Howard Hughes Medical Institute (HHMI) Early Career Scientists.

05/15/2009: The one hundred announced

MGH Hotline 5.15.09 Exactly 100 flowers were planted in the Howard Ufelder, MD, Healing Garden April 28 to recognize the newly announced members of the one hundred – 100 groups and individuals who are making a difference in cancer care.

05/04/2009: Screening the options: Dialogue an important part of prostate cancer screening and treatment

Prostate cancer experts at the Massachusetts General Hospital Cancer Center weigh in on best guidelines for screening.

04/13/2009: The Partnership Symposium: Conquering Breast Cancer

On Sunday, April 26, the 92nd Street Y in New York City brings together three of the leading breast cancer organizations, top scientists and researchers, and breast cancer survivors to provide clear and current information on the disease.

04/08/2009: Tiny sacs released by brain tumor cells carry information that may guide treatment

Exosomes deliver factors that promote tumor growth and may serve as blood biomarkers.

03/30/2009: Angiogenesis inhibitor improves brain tumor survival by reducing edema

The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema – the swelling of brain tissue – and not from any direct anti-tumor effect.

03/23/2009: Her toughest opponent: Cathy and her team take on pancreatic cancer

Cathy partnered with Cancer Center physicians and staff to fight pancreatic cancer and regain her active lifestyle.

03/23/2009: Breast Cancer Fashion Fundraiser April 30

03/18/2009: Chemotherapy desensitization

What happens when you are allergic to a treatment that could save your life?

03/09/2009: Genetic profiling

Massachusetts General Hospital Cancer Center opens molecular pathology lab to genetically profile all patient tumors

03/06/2009: Both Latino and non-Latino women likely to accept HPV vaccination for selves and children

Most women responding to a survey conducted at MGH clinics indicated they would be willing to be vaccinated against the human papillomavirus and to have their daughters and even sons vaccinated in order to prevent cancer in their children. The report also found that Latino women are just as likely, if not more so, to accept HPV vaccine as non-Latinos.

03/06/2009: Personalizing cancer care

MGH Hotline 3.6.09 Cancer is most commonly classified by its location – in the lungs, liver, breast or elsewhere. In truth, however, every tumor is unique, and the genetic makeup of a tumor can often be more important than where it is located.

02/17/2009: New imaging technology shows promise in future cancer treatment

The first combined MRI/PET machine is being tested on brain cancer patients.

01/29/2009: MGH Cancer Center now offers pencil-beam proton therapy treatment

The MGH Cancer Center has added pencil-beam scanning to the radiation therapy modalities offered at the hospital’s Burr Proton Therapy Center.

01/23/2009: A gift in loving memory of a father

MGH Hotline 1.23.09When his father Kenneth died of a brain tumor at age 48 in 2005, then 17-year-old Justin Stanton knew he wanted to honor his father's memory in a way that would help others.

01/09/2009: Cancer genome research

The MGH Cancer Center and the Wellcome Trust Sanger Institute of the United Kingdom have begun a new alliance in cancer genome research.

01/09/2009: Erika Barrett, NP, honored

Erika Barrett, NP, of the MGH Cancer Center, recently was chosen the first recipient of the center's Hematology-Oncology Nurse Practitioner Excellence Award.

12/11/2008: Cancer Center Media Coverage

Browse news articles across local and national media outlets.

12/10/2008: Hormone therapy for prostate cancer does not appear to increase cardiac deaths

Treating prostate cancer patients with drugs that block hormonal activity does not appear to increase the risk of death from cardiovascular disease, according to a study led by MGH researchers

12/09/2008: Combining targeted therapy drugs may treat previously resistant tumors

Blocking two cell signaling pathways leads to dramatic shrinkage of K-Ras-mutated tumors in animal model

12/05/2008: In General

MGH Hotline: 12/05/08

12/05/2008: MGH Cancer Center staff visit Kazakhstan

MGH Hotline 12/05/08: A multidisciplinary team from the MGH Cancer Center recently traveled to Kazakhstan’s capitol Astana to work with the city’s Department of Health to improve the oncology services at a local hospital.

12/05/2008: MGH Cancer Center staff visit Kazakhstan

MGH Hotline 12/05/08 A multidisciplinary team from the MGH Cancer Center recently traveled to Kazakhstan’s capitol Astana to work with the city’s Department of Health to improve the oncology services at a local hospital.

12/05/2008: The fight against lung cancer lights up

MGH Hotline 12/5/08 Prudential Tower Hundreds of individuals supporting the fight against lung cancer joined special guests from the MGH, the Massachusetts chapter of the Lung Cancer Alliance, WCVB-TV’s Heather Unruh, and state public health and public policy leaders for a touching candlelight vigil at the Prudential Center Courtyard Nov. 20.

11/16/2008: Tiny sacs released by brain tumor cells carry information that may guide treatment

MGH researchers have found that tiny membrane-covered sacs released from glioblastoma cells contain molecules that may help guide treatment of the deadly brain tumor.

06/11/2008: Massachusetts General Hospital ranked on U.S. News national honor roll

The third oldest general hospital in the United States and the oldest and largest hospital in New England, Mass General continues its tradition of excellence today. The hospital is consistently ranked among the top five hospitals in the nation by U.S. News & World Report. In 2008, Mass General was redesignated a Magnet hospital, the highest honor for nursing excellence awarded by the American Nurses Credentialing Center.

04/18/2007: Sridhar Ramaswamy, MD, awarded the Sidney Kimmel Foundation Award in Translational Research

The Kimmel Scholar Awards were created in 1997 to further the careers of gifted, young scientists involved in cancer research.

02/01/2012: Advances in Cancer

Advances in Cancer: Winter 2012 edition
Advances in Cancer: Winter 2012 edition

09/01/2011: MGH Fund Update Summer 2011

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The MGH Fund Update is a publication for supporters of the MGH Fund, Mass General's fundamental resource for providing life-saving patient care, advancing biomedical research, and creating healthcare solutions in our community and around the globe.

06/09/2011: Advances in Cancer

Advances in Cancer: Spring 2011
Advances in Cancer: Spring 2011 edition

06/01/2011: Synergy Magazine: A Year in Review/A Look to the Future 2011

Synergy Magazine
Bold New Options: Pioneering the Next Generation of Cancer Care

01/07/2011: Advances in Cancer

Read Advances in Cancer
Advances in Cancer: Winter 2011 edition

01/01/2011: Advances at Mass General

Advances at Mass General, winter 2011 issue
Read Advances at Mass General, a bi-annual news magazine published for our colleagues from the physicians of Massachusetts General Hospital.

01/01/2011: Mass General Magazine

Read more at www.massgeneralmag.org
Mass General Magazine is a publication for supporters and friends of Massachusetts General Hospital that takes you inside the hospital and explores its patient care and research programs here and around the world. It features rich photo essays and in-depth profiles from across the Mass General world.

06/14/2010: Synergy Magazine: Spring 2010

Read Synergy Magazine
This issue, entitled "A year in review...a look to the future" highlights the Cancer Center's progress in understanding, preventing and curing cancer over the last year.

06/07/2010: Advances at the Mass General Cancer Center - Summer 2010

Advances at the Mass General Cancer Center - Summer 2010
Introducing ADVANCES at the MASS GENERAL CANCER CENTER, a new physician publication of the Massachusetts General Hospital Cancer Center. This newsletter will update you twice a year on how Mass General Cancer Center researchers and clinicians are helping to transform cancer care by approaching new thresholds in treatment that help us better understand the disease.
Subscribe to Advances at the Mass General Cancer Center

10/09/2009: Synergy Magazine: Fall 2009

Synergy: Fall 2009
This issue of Synergy focuses on sarcoma and soft tissue cancers.

04/01/2009: Proto: Dispatches from the frontiers of medicine

Proto magazine, Spring 2009 issue
The Spring 2009 issue of Proto, a magazine that reaches 75,000 thought leaders nationwide, explores new developments in organ transplantation, the relationship between public art and public health, creating stem cells from an unlikely source and the rollercoaster history of hormone replacement therapy.

01/01/2009: Proto: Dispatches from the frontiers of medicine

Proto magazine, Winter 2009 issue
The Winter 2009 issue of Proto, a magazine that reaches 75,000 thought leaders nationwide, features sociable robots, the model organism C. elegans, restorative neuroscience, micro medical practices and an elite set of HIV patients.

12/11/2008: A Guide to the Cancer Center for Patients and Families

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A guide to treatment programs, as well as support, education and wellness services available to patients and families.

12/01/2008: Synergy

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Synergy

07/01/2008: Synergy- Summer '08

View this publication
Synergy: Summer edition, 2008

12/12/2007: Journeys

View this publication
Massachusetts General Hospital Annual Report 2007

01/11/2007: Vision

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Vision is a magazine for the MGH community, donors and friends. In this issue read about the Massachusetts General Hosptial Cancer Center.

06/07/2012: the one hundred

Save-the-date for the 5th annual the one hundred event: June 7, 2012

04/15/2012: First Annual Let's Cure Cancer Dinner

First Annual Let's Cure Cancer Dinner

04/14/2012: First Annual Let's Cure Cancer Golf Tournament & Luncheon

First Annual Let's Cure Cancer Golf Tournament and Luncheon

03/29/2012: Runway Ten: Celebrating Survivorship through Fashion

Join us on March 29 as ten caregivers and ten cancer survivors take to the runway as part of Runway Ten, an event for the Mass General Cancer Center.

03/06/2012: Illuminations Opening Reception

Join the Massachusetts General Hospital Cancer Center for its Illuminations Program Opening Reception on March 6, 2012.

03/03/2012: Ladies Night Out

Don't miss the fun! Join us for the 2nd Annual Ladies Night Out to benefit the ESSCO Breast Cancer Research Fund & Mass General Cancer Center!

12/24/2011: Blackstone's of Beacon Hill Christmas Eve Event

Join Blackstone's Mystery Ornament Project for a fun evening of mystery and puzzle solving to benefit pediatric cancer research

12/11/2011: HOPES Program Benefit Jazz Concert

Upcoming concert with 2011 Grammy winner, Esperanza Spalding! To benefit HOPES music and art therapy program at Mass General Cancer Center.

12/01/2011: Illuminations Opening Reception

October 2011-January 2012 Illuminations Exhibit Opening Reception

11/17/2011: The Friends of Massachusetts General Hospital Cancer Center 19th Annual Fall Benefit

The Friends of the Massachusetts General Hospital Cancer Center invite you to a Cocktail Buffet, Auction and Festive Evening November 17, 2011

11/12/2011: Julie Fund Gala

Join us at the Park Plaza Hotel for an evening of music and dancing in support of women's cancers research and education. The Julie Fund was established by the McAvinn family and friends in partnership with Massachusetts General Hospital and Partners Healthcare.

11/11/2011: Surgery of the Thyroid & Parathyroid Glands

This course is intended to be a two-day comprehensive review and update of surgery of the thyroid and parathyroid glands. Preoperative work up of both thyroid and parathyroid surgical disease will be discussed with an emphasis on fine needle aspiration and preoperative parathyroid localization imaging options.

11/06/2011: Lucca Wine Tasting

Come enjoy an evening of wine tasting while raising money for breast cancer research at Massachusetts General Hospital.

11/05/2011: Breathe Deep Boston 5K Walk

Join the LUNGevity Foundation on November 5 for the Breathe Deep Boston 5K Walk. LUNGevity proudly supports the Mass General Cancer Center.

11/03/2011: Wilkins Visiting Professor Lecture

Bryan F. Meyers, MD, Patrick and Joy Williamson Professor of Surgery at the Washington University School of Medicine, will present the 2011 Wilkins Visiting Professor Lecture.

11/03/2011: 2nd Annual TargetCancer Auction and Benefit Concert

Please join TargetCancer for an evening of music, mingling and more as we raise funds for rare cancer research.

10/29/2011: 3rd Annual Angel's Masquerade Ball

This event will raise funds for melanoma research and to spread awareness of the dangerous effects of overexposure to sunlight and tanning.

10/29/2011: Score4More Charity Basketball Game

Join in the fun at a Score4More charity basketball game and raffle to benefit breast cancer research and prevention.

10/29/2011: Friends Fighting Breast Cancer Halloween Costume Party

Come join in the Halloween fun and support breast cancer research! Prizes for best costume, dinner and dancing!

10/25/2011: Runway for Recovery

A Fashion show, silent auction & raffle to benefit families who have lost mothers to breast cancer.

10/20/2011: Friends Fighting Breast Cancer Michael Kors Private Shopping Event

Exclusive evening of cocktails, hors d'oeurves and shopping! Fifteen percent of sales will be donated to the FFBC benefiting the Mass General Cancer Center.

10/15/2011: Filomena's Five Years Cancer-free Party

Join us at Filomena's Five Years Cancer-free Party! Have fun, celebrate life and raise funds for the Mass General Cancer Center!

10/15/2011: Lt. Danny Boyle Memorial Run/Walk

Join us for the Lt. Danny Boyle Memorial Run/Walk on October 15 benefiting the Brain Tumor Education and Research Fund at Mass General, in memory of Lt. Danny Boyle.

10/15/2011: Homecoming Hustle 5K Run/Walk

Join us for the Homecoming Hustle 5K Run/Walk on October 15, benefiting Breast Cancer Research at Mass General.

10/06/2011: 16th Annual ESSCO-MGH Breast Cancer Research Fund Benefit

The ESSCO-MGH Breast Cancer Research Fund will host its 16th Annual Benefit on October 6, 2011. Join the fun!

10/05/2011: Boston Golfers Against Cancer Dinner

Join the Boston Golfers Against Cancer for their 6th Annual Dinner on October 5 at Four Seasons Hotel. Proceeds benefit Mass General Cancer Center.

10/02/2011: 6th Annual Breast Friends Walk

Join us for the 6th Annual Breast Friends Walk Around the Neck. The walk begins on Devereux Beach and follows a 3-mile course around beautiful Marblehead Neck. All proceeds go to support the Mass General Hospital Breast Cancer Patient Support Fund.

10/02/2011: Woburn Students Trying to Make a Difference - 2 Mile Walk

An annual two-mile walk around Horn Pond to raise funds for the Gillette Center for Breast Cancer at Massachusetts General Hospital.

10/01/2011: Frank Weber Memorial Golf Tournament

A golf tournament in honor of Frank Weber to raise funds for Dr. Lawrence's melanoma and liver cancer research at Mass General.

09/25/2011: Third Annual Nancy's Walk

Nancy's Walk raises funds for Pancreatic Cancer Research at Massachusetts General Hospital

09/24/2011: 5th Annual Granara-Skerry 5K Walk/Run

Participate in the 5th Annual Granara-Skerry 5k Walk/Run to Benefit Pancreatic Cancer Research at MGH

09/16/2011: Be a Piece of the Solution

An event in honor of Judy Shanley to benefit lung cancer research and care at Mass General Hospital.

09/16/2011: Knocking Out Cancer

American Fighting Organization will be hosting their first event ever: Knocking Out Cancer to raise money for the Mass General Cancer Center

09/12/2011: 1st Annual Gary R. Letourneau Jr. Memorial Golf Outing

The Letourneau family invites you to join in raising money for the MGH Pediatric Oncology Clinic in memory of Gary Letourneau.

09/10/2011: Townsend Fire-EMS Relief Association Golf Outing

A golf tournament in memory of a Townsend Firefighter who was treated at MassGeneral Cancer Center.

08/20/2011: Ovarian Cancer Survivors Course

The Foundation for Women's Cancer is pleased to offer this Free full day course for all cancer survivors, friends, family members and others who are interested in hearing from the leading U.S. experts in ovarian cancer research. These experts will share new information about ovarian cancer, and time for questions and answers will be provided.

05/08/2011: 8th Annual Purple Ribbon 5K Run/Walk

The Michelle Cadorette Fund for Malignant Thymoma Research hosts a 5K Run/Walk to benefit thymoma research at Mass General Cancer Center

04/09/2011: Cancer Survivors' Day

Living with Cancer: Navigating the Cancer Journey

03/08/2011: An Evening of Celebration, Shopping and Glamour

Massachusetts General Hospital Cancer Center honors and celebrates cancer patients, survivors, caregivers and physicians as they take to the runway.

11/21/2009: Julie Fund Gala

Enjoy cocktails, dinner, dancing and a live auction -- all to benefit the Julie Fund for Women's Cancers.

11/12/2009: Friends of the Cancer Center 2009 Event

The Friends of the Mass General Cancer Center present a Holiday Shopping Benefit at Saks Fifth Avenue

10/18/2009: When a Child Knows Someone with Cancer

Helping Young Children Cope with the Cancer Diagnosis of a Loved One

06/03/2009: theonehundred

06/03/2009: theonehundred