For Information
617-724-1124

The Bone Marrow Transplant Program was established ten years ago. Its research mission is to develop novel methods of allogeneic stem cell transplantation to maximize the separation of graft versus host disease (GVHD) and graft versus tumor (GVT) effect in both the HLA-matched and mismatched settings.

The purpose of our research is to more safely perform allogeneic stem cell transplants across HLA barriers so that virtually all patients will have an available related donor, and to establish the necessary hematopoietic chimerism for our tolerance-induction protocols.

Research Protocols

• Allogeneic non-myeloablative conditioning and delayed donor leukocyte infusions for HLA-matched peripheral blood stem cell transplantation
• Non-myeloablative HLA-mismatched ex vivo T-cell depleted stem cell transplantation for hematologic malignancies
• Combined bone marrow transplant and renal transplant for multiple myeloma with end-stage renal disease
• Renal allograft tolerance through mixed chimerism
• Phase I study of sequential cord blood transplants

Read more about ongoing clinical research in bone marrow transplants.