The images demonstrate normal white matter fibers in the brain - absent/disrupted prior to treatment but returning to normal after treatment. By reducing tumor mass and edema the normal white matter fibers are restored.

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These images show MRI-based estimates of white matter tracts, the "wires" that connect different parts of the brain.

• On the left is a patient before treatment, and on the right, one month after treatment.
• On the right, more white matter tracts are visible, probably because of resolution of brain edema.

More investigations are needed to better understand the impact of these treatments.

For Information on Athinoula A. Martinos Center for Biomedical Imaging: www.nmr.mgh.harvard.edu or www.martinos.org