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Selected Articles Choy, E.*, Yelensky, R.*, Bonakdar, S., et al. (2008) "Genetic Analysis of Human Traits In-Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines." PLOS Genetics, 4(11):e1000287. *equally contributing first-authors Duan, Z.*, Choy, E.*, Harmon, D., Yang, C., Ryu, K., Schwab, J., Mankin, H., and Hornicek, F. (2009) "Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picrophodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines." Mol. Cancer Ther. 8(8):2122-30. Epub 2009 Jul 28. *equally contributing first-authors
Choy, E., Digumarthy, S., and Koplin, S. (2009) "A 23 year old man with cough, hoarseness, and fever." Case Records of the Massachusetts General Hospital, New Engl J Med. 361(21):2080-7.
Choy, E. and Philips, M.R. (2000) "Expression and activity of a prenylcysteine-directed carboxyl methyltransferase." Methods in Enzymology 325, 101-114.
Dai, Q., Choy, E., Chiu, V., Romano, J., Slivka, S.R., Steitz, S.A., Michaelis, S., and Philips, M.R. (1998) "Mammalian Prenylcysteine Prenyltransferase is in the Endoplasmic Reticulum." Journal of Biological Chemistry 273(24), 15030-15034.Choy, E., Chiu, V.K., Silletti, J., Feoktistov, M., Morimoto, T., Michaelson, D., Ivanov, I.E., and Philips, M.R. (1999) "Endomembrane Trafficking of Ras: the CAAX Motif Targets Proteins to the ER and Golgi." Cell 98, 69-80.
A young sailor from Maine will compete with his team for a gold medal in the Paralympic sailing events in Rio de Janeiro. Hugh Freund, 28, who lost his lower leg to cancer as a teenager, will race for the U.S. Sailing Team along with two other disabled athletes as part of a team in the Three-Person Keelboat (Sonar) event.
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