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The Tumor Imaging Metrics Core (TIMC):
Reliable tracking of changes in lesion size or metabolism is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.
Core Co-Director: Gordon Harris, PhD (MGH) Core Co-Director: Annick Van den Abbeele, MD (DFCI)
Core Manager: Gina Basinsky Tel: firstname.lastname@example.org
Vikram Kurra, MD Tel: email@example.com
Supriya Somarouthu, MD Tel: firstname.lastname@example.org
Samira Farough, MD Tel: email@example.com
Nency Joshipura, MD Tel: firstname.lastname@example.org
Atul Padole, MD Tel: email@example.com
Location of Core: 25 New Chardon Street Suite 501, Boston, MA 02114
Included in the TIMC user fees are the following services; consultation with Trial PIs prior to trial initiation, image study capture from DF/HCC centers, image study archival for the length of the trial, tumor measurements as specified in the protocol, database management of measurement results and image snapshots, web-based results reporting and assistance with trial audits with respect to the image analysis components of the trial.
The TIMC offers consultative services to clinical trials investigators at no additional cost to DF/HCC investigators. The goal of the consultative service is to optimize clinical trials’ protocol design for imaging acquisition and analysis methods so that trials are established with appropriate and optimal imaging methods.
TIMC service fees (per scan). Updated 7-April 2017
RECIST – Response Evaluation Criteria for Solid Tumors (linear). WHO – World Health Organization criteria (bi-directional). IWRC – International Workshop Response Criteria (bi-directional). Cheson – (sum of products of perpendicular diameters). An additional charge of one scan time-point will be applied if measurements must be repeated from baseline; i.e. if new target lesions are identified for a subject in accordance with Cheson response criteria guidelines. SUV – Standard Uptake Value, using body weight formula Choi – RECIST plus density measurements on CT scans w/contrast 3D Volume - Includes modified RECIST measurements for brain PCWG- Prostate Cancer Working Group IMWG- International Myeloma Working Group
Core Manager Gina Basinsky Tel: 617-643-7812
TIMC Help Desk Tel: firstname.lastname@example.org
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