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Molecular Profiling Laboratory

The Molecular Profiling Laboratory (MPL) is one of the Cancer Center research centers that provide technological support to Cancer Center investigators.

Overview
Group Members

Overview

Technologies available through MPL include Affymetrix DNA microarray (mRNA expression, tiling, resequencing, promoter, and SNP), RTQ-PCR (TaqMan assay), nucleic acid characterization (microscale UV spec and Agilent Bioanalyzer microcapillary electrophoresis), basic bioinformatics (array data analysis and computational data profiling), and RNAi knockdown of human and mouse genes using the shRNA lentivirus library clones generated by The RNAi Consortium (TRC) of the Broad Institute.

MPL is presently developing a laboratory automation system for RNAi knockdown screening using this resource.

Group Members

Toshihiro Shioda, MD, PhD
Kathryn Coser
Shannon Smith
Keiko Shioda
Heather Ostendorff

Research at Mass General

Discover the largest hospital-based research program in the U.S. and how clinicians and scientists chart new terrain in biomedical research to treat and prevent human disease and bring the latest advances to patient care