Cancer Genetics
The Center for Cancer Risk Assessment provides comprehensive genetic counseling and testing services for those who may be at increased risk of hereditary cancer.
Information by disease clinic
Some individuals have an increased risk of developing cancer based on their personal and/or family history. Several members, across generations, may be affected. The Center for Cancer Risk Assessment provides evaluation, counseling, testing and referral for appropriate ongoing monitoring, treatment and follow-up for hereditary cancers, including:
- Breast
- Gynecological cancers: ovarian, uterine and fallopian tube
- Gastrointestinal: colon, rectal, pancreatic and gastric
- Genitourinary: kidney
- Endocrine: thyroid, pituitary and adrenal
- Skin: melanoma
Our center also provides counseling and genetic testing for the following syndromes:
- Hereditary breast and ovarian cancer syndrome (including the BRCA1 and BRCA2 mutations)
- Cowden syndrome
- Li-Fraumeni syndrome
- Hereditary non-polyposis colorectal cancer syndrome (Lynch syndrome)
- Colon polyp syndromes: familial adenomatous polyposis, MYH-associated polyposis, juvenile polyposis
- Hereditary diffuse gastric cancer syndrome
- Peutz-Jeghers syndrome
- Von-Hipple-Lindau syndrome
- Birg-Hogg-Dube syndrome
- Hereditary paraganlioma syndrome
- Multiple endocrine neoplasia, type 1 and type 2 syndrome
- Hereditary leiomyomatosis and renal cell cancer syndrome
- Hereditary papillary renal cell cancer syndrome
- Familial atypical multiple mole melanoma syndrome
Innovative Approaches Advance Clinical Care In addition to the comprehensive services provided by the Center for Cancer Risk Assessment, patients in our program have access to all the resources of Massachusetts General Hospital. This allows every patient’s complete care to be coordinated by a multidisciplinary team of specialists all in one place.
Patients who learn they have a genetic predisposition to cancer have options that can also be fully managed within Mass General, including:
- Ongoing surveillance and monitoring of status or precancerous conditions
- Immediate action and treatment at the appropriate time
- Genetics counseling and testing for family members
- Prophylactic surgery, care and follow-up
- Access to Massachusetts General Hospital Fertility Center's Preimplantation Genetic Diagnosis Program, which helps couples with an increased risk for a specific genetic abnormality to have a child unaffected by that particular disease
- Cancer treatment and follow-up
Multidisciplinary Patient Care All patients of the Cancer Center are cared for by a multidisciplinary team of specialists and those who come to the Center for Cancer Risk Assessment are no exception. Our program includes:
- Certified Genetic Counselors experienced in helping patients gather the information they need to make informed healthcare decisions
- Access to psychiatrists and social workers to help cope with the emotional component of genetic testing
- Collaborations with the Cancer Center’s expert medical staff
- Collaborations with Mass General specialist outside the Cancer Center
Developing Better Therapies through ResearchLike all treatment centers within the Cancer Center, our program is highly involved in research. We lead and participate in studies to develop better understanding of the genetic causes of several cancer syndromes, as well as studies to advance cancer treatment and screenings.
HOPES Program
The HOPES Program provides free wellness services, plus education and support workshops for patients with cancer, their families and their friends. Our services focus on helping you take care of your whole self – mind, body and spirit.
Maxwell V. Blum Cancer Resource Room
The Maxwell V. Blum Cancer Resource Room at the Massachusetts General Hospital Cancer Center provides cancer patients and their families with information and resources for living with cancer.
Illuminations Program
Illuminations is a rotating art exhibit displayed in the Massachusetts General Hospital Cancer Center. The program aims to enlighten and encourage patients and their loved ones by enhancing our environment of care.
Oncology Chaplaincy
Our oncology chaplain is familiar with the unique needs of those with cancer.
von Hippel-Lindau Disease
December and January episodes of the television show “Grey’s Anatomy” featured a storyline about von Hippel-Lindau (VHL) disease, a rare but serious genetically-inherited condition that can cause abnormal blood vessel growth and tumor development. Gayun Chan-Smutko, MS, CGC, a genetic counselor in the Cancer Center’s von Hippel-Lindau Clinic discusses testing, screening and treatment options for VHL.
Staff Snapshot
Senior Genetic Counselor, Gayun Chan-Smutko, MS, CGC
Cancer Center celebrates the one hundred
MGH Hotline 6.10.11 One individual can make an incredible difference for a patient with cancer.
HOPES Program
The HOPES Program provides free wellness services, plus education and support workshops for patients with cancer, their families and their friends. Our services focus on helping you take care of your whole self – mind, body and spirit.
Maxwell V. Blum Cancer Resource Room
The Maxwell V. Blum Cancer Resource Room at the Massachusetts General Hospital Cancer Center provides cancer patients and their families with information and resources for living with cancer.
Illuminations Program
Illuminations is a rotating art exhibit displayed in the Massachusetts General Hospital Cancer Center. The program aims to enlighten and encourage patients and their loved ones by enhancing our environment of care.
Oncology Chaplaincy
Our oncology chaplain is familiar with the unique needs of those with cancer.
Cancer Center
55 Fruit StreetBoston, MA 02114
Phone: 617-726-5130

Request an appointment at the Cancer Center 
Contact the Cancer Center to schedule an appointment with one of our cancer specialists



