Treatment Programs

Uterine Cancer (Uterine Sarcoma)

Expert, compassionate care for patients with all types and stages of uterine cancer.

Patients at our Gillette Center for Gynecologic Oncology are treated by gynecologic cancer specialists experienced in local and advanced uterine cancer. We offer expert care for women with:

  • Leiomyosarcoma (cancer that begins in smooth muscle cells)
  • Mixed mullerian tumors [carcinosarcoma]
  • Endometrial stromal sarcoma (cancer that begins in connective tissue cells).
  • Adenosarcomas

Learn more about endometrial cancer.

Innovative ApproachesAmong the innovative approaches offered here are:

  • Highly coordinated care by a team of gynecologic cancer specialists
  • Access to novel therapies through clinical trials
  • Robotic-assisted and minimally invasive surgeries
  • Advanced radiation therapy techniques, including technologies offered at only a few other centers nation-wide

Multidisciplinary Patient Care Your personalized treatment plan will be developed by experts from an array of gynecologic cancer specialties. Depending on the stage and other characteristics of your cancer, this treatment plan may include surgery, chemotherapy, radiation, or a combination of these therapies.

The specialists involved in your care may include:

  • Pathologists specializing in gynecologic cancers who provide a precise diagnosis of your cancer.
  • Radiologists specializing in gynecologic malignancies that help guide the selection of appropriate imaging tests and provide accurate interpretation.
  • Surgical Oncologists experienced in the latest minimally-invasive gynecologic surgery approaches.
  • Medical Oncologists to prescribe the most effective chemotherapy treatments and discuss available clinical trials
  • Radiation Oncologists who specialize in delivering the highest therapeutic dose while protecting healthy tissue
  • Oncology nurses and nurse practitioners who specialize in cancer care
  • Oncology psychiatrists and social workers experienced in helping with the cognitive side effects of cancer and treatment, as well the emotional and spiritual aspects of the cancer experience
  • A nutritionist to help you with questions about diet and nutrition during treatment
  • Palliative care providers to improve quality of life

Members of your care team meet regularly with you and your referring physician to ensure clear communication and seamless coordination of care.

Gynecologic Oncology – Advanced Care for uterine cancer at Mass General Hospital

Expertise in Diagnosing and Staging CancersOur pathologists are sub-specialized in identifying gynecologic malignancies. This expertise leads to more accurate diagnosis and staging, which forms the basis for your treatment.

Our gynecologic cancer pathologists are internationally recognized and consulted on the diagnosis of uterine cancer. They participate in weekly tumor board meetings, sharing information about each patient’s unique cancer with the entire treatment team to help guide care planning.

Our skilled radiologists employ all the most advanced imaging methods and are well versed in performing image-guided interventional procedures such as CT-guided biopsy.

Advancing Care by Improving MedicineBased on your overall health and the stage and other characteristics of your cancer, your medical oncologist may recommend traditional or novel approaches to chemotherapy such as:

  • Cancer immunotherapy, which entails vaccinating women with their own modified tumor cells or immune stimulants to bolster the body’s response to cancer therapies
  • Therapies for drug-resistant tumors that help boost sensitivity to chemotherapy
  • Targeted therapies

Because we have a high number of patients using these approaches, we are familiar with medical, lifestyle, and complementary approaches, such as acupuncture, for minimizing side effects.

Excellence in Surgical CareMass General is a recognized leader in gynecologic cancer surgery. We treat thousands of patients annually, and studies show that such high-volume experience results in improved patient outcomes. Because of the numbers of patients seen here annually, our gynecologic cancer surgeons are highly experienced in the treatment of both rare and common cancers. Our skilled surgical teams offer the latest surgical innovations with emphasis on minimally invasive procedures.

Pioneering Radiation TherapiesWe offer a full spectrum of radiation therapy treatments including some approaches available at just a few other medical centers in the U.S. Depending on the type and stage of your disease, your treatment may include:

  • Proton beam therapy
  • Intraoperative radiation therapy
  • Concurrent chemotherapy and radiation
  • Intensity modulated radiation therapy
  • Outpatient high-dose rate brachytherapy
  • Exceptional precision to minimize the impact of treatment on sexual and hormonal functions

Learn more about radiation therapy. 

Treating Cancer through Clinical TrialsAs part of one of the nation’s leading centers for gynecologic cancer research, our researchers are developing promising new treatments for these cancers. We have one of New England’s largest clinical trial programs. Whether you have early or advanced uterine cancer, you may be eligible to participate in one of the following studies:

  • Techniques to administer chemotherapy throughout the abdomen to improve outcomes and reduce side effects
  • Novel agents that kill tumors by blocking their blood supply
  • Immunotherapy, which stimulates a patient’s own immune system to fight the tumor
  • New imaging technologies for evaluating the extent of disease
  • Analyzing the effectiveness of treating patients with combinations of radiation therapy and chemotherapy
  • Reducing side effects associated with radiation therapy.
  • Therapies for drug-resistant tumors
  • Quality of life therapies
  • The role of alternative and complementary therapy in cancer care

View our open trials for uterine cancer.

Developing Better Therapies through Research

Our translational research program ensures that clinical observations about the efficacy of new therapies is shared with laboratory scientists to help focus basic research on the most effective and most easily tolerated new therapeutic approaches, including new uses of existing targeted drugs and new classes of these drugs.

Recent bench to bedside lab work at the Vincent Center for Reproductive Biology has identified sarcoma mutations which may allow for targeted therapy while decreasing side effects

Uterine Cancer

Cancers that occur in each part of the uterus have their own names, such as cervical cancer or endometrial cancer, but are sometimes broadly defined as uterine cancer because the structure is part of the uterus.

The Katherine A. Gallagher Integrative Therapies Program

The Katherine A. Gallagher Integrative Therapies Program focuses on improving the quality of life and well-being of Cancer Center patients, their families and friends through free wellness services such as acupuncture and yoga. These services help you take care of your whole self — mind, body and spirit.

Maxwell V. Blum Cancer Resource Center

The Maxwell V. Blum Cancer Resource Center is a program that offers a range of support resources around the Cancer Center. The center has an ongoing mission to make support services, as well as respite and community-building areas, more accessible to patients and families throughout the Cancer Center.

The PACT Program

The Marjorie E. Korff PACT program at the Massachusetts General Hospital Cancer Center provides psycho-educational support for parents who are patients.

Oncology Chaplaincy

Our oncology chaplain is familiar with the unique needs of those with cancer.

Home Disconnect

A home infusion pump may be part of your treatment plan. In some cases, you may have the option for disconnecting the chemotherapy from home. If this option applies to you, and you would prefer to disconnect from home, this instructional video will reinforce the teaching provided to you by your nurse in the Mass General cancer Center

The following related clinical trials and research studies are currently seeking participants at Massachusetts General Hospital. Search for clinical trials and studies in another area of interest.

The Katherine A. Gallagher Integrative Therapies Program

The Katherine A. Gallagher Integrative Therapies Program focuses on improving the quality of life and well-being of Cancer Center patients, their families and friends through free wellness services such as acupuncture and yoga. These services help you take care of your whole self — mind, body and spirit.

Maxwell V. Blum Cancer Resource Center

The Maxwell V. Blum Cancer Resource Center is a program that offers a range of support resources around the Cancer Center. The center has an ongoing mission to make support services, as well as respite and community-building areas, more accessible to patients and families throughout the Cancer Center.

The PACT Program

The Marjorie E. Korff PACT program at the Massachusetts General Hospital Cancer Center provides psycho-educational support for parents who are patients.

Oncology Chaplaincy

Our oncology chaplain is familiar with the unique needs of those with cancer.

Home Disconnect

A home infusion pump may be part of your treatment plan. In some cases, you may have the option for disconnecting the chemotherapy from home. If this option applies to you, and you would prefer to disconnect from home, this instructional video will reinforce the teaching provided to you by your nurse in the Mass General cancer Center

Cancer Center

55 Fruit Street
Boston, MA 02114

Phone: 617-726-5130

Discover the Cancer Center patient experience

Our approach to patient care unites cancer specialists across the hospital to create a personalized treatment plan for each patient, ensuring the best possible outcomes.