THE CENTER FOR CANCER RESEARCH
The unique strengths of the Center for Cancer Research (CCR) are the exceptional quality of its faculty and the ways in which the CCR's basic scientists collaborate with Mass General’s leading oncologists, surgeons, radiologists, pathologists, and other health care professionals to advance the frontiers of cancer medicine.
Read the Center for Cancer Research's 2014 Annual Report
News and Events
- Noncovalent Interactions with SUMO and Ubiquitin Orchestrate Distinct Functions of the SLX4 Complex in Genome Maintenance.
- Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.
- EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma.
- Johnathan Whetstine receives lung cancer discovery award from the American Lung Association
- View more Center for Cancer Research news
- Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.
- Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis.
- A Coding Single Nucleotide Polymorphism in Lysine Demethylase KDM4A Associates with Increased Sensitivity to mTOR Inhibitors.
- Patient-derived models of acquired resistance can identify effective drug combinations for cancer.
- Genetic and epigenetic fine mapping of causal autoimmune disease variants.
- Crizotinib in ROS1-Rearranged Non-Small-Cell Lung Cancer.
- Small molecules facilitate rapid and synchronous iPSC generation.
- Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells.
- Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
- Brain tumor cells in circulation are enriched for mesenchymal gene expression.