THE CENTER FOR CANCER RESEARCH
The unique strengths of the Center for Cancer Research (CCR) are the exceptional quality of its faculty and the ways in which the CCR's basic scientists collaborate with Mass General’s leading oncologists, surgeons, radiologists, pathologists, and other health care professionals to advance the frontiers of cancer medicine.
Read the Center for Cancer Research's 2014 Annual Report
Postdoc Fellow Positions
- SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes.
- Comprehensive assessment of cancer missense mutation clustering in protein structures.
- RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance..
- Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase.
- Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation.
- Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
- Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.
- Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
- Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage.
- Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.
- A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.
- The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
- Sridhar Ramaswamy, MD was elected a 2015 MGH Research Scholar.
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