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Center for Cancer Research
Postdoctoral Research Fellowship positions are available in the Center for Cancer Research (CCR) at the Massachusetts General Hospital.
Postdoctoral Research Fellowship positions are available in the Center for Cancer Research (CCR) at the Massachusetts General Hospital (www.massgeneral.org/cancerresearch). The CCR is comprised of more than 40 laboratories engaged in basic and translational cancer research across a variety of disciplines, including cancer genetics, epigenetics, metabolism, imaging, diagnostics, signaling, stem cell biology and tumor immunology. The center hosts a large number of pre- and post-doctoral trainees, with a robust schedule of seminars, journal clubs, and lab meetings. This highly collaborative community is housed in at the MGH Charlestown Navy Yard facility in Boston, Massachusetts, with close access to collaborators at the Broad Institute, MIT, Harvard, and others.
Mark Cobbold, PhD, MRCP. The Cobbold Laboratory focuses on understanding how the healthy human immune response is able to recognize and target cancerous cells, and when it fails, how it could be strengthened. We are particularly interested in posttranslationally modified neoantigens as well as mechanisms to modulate tumor antigenicity to allow existing tumor-resident anti-viral immunity to instead target cancerous cells. Specific expertise in protein expression, antibody engineering, T-cell biology/culture, T-cell based immunoassays, and/or single-cell molecular sequencing techniques are preferred.
Jonathan Hoggatt, PhD. The Hoggatt Laboratory is broadly interested in the niche regulatory mechanisms that govern tissue regeneration, particularly regulation by macrophages, and have specific interest in translational science for bone marrow transplantation and other treatments. We have also identified a unique “highly engraftable” hematopoietic stem cell for further discovery efforts. A strong foundation in cell, developmental, cancer, or molecular biology is necessary. Specific expertise in macrophage biology or hematopoietic stem cell biology is welcome, though all strong and qualified candidates will be considered.
Timothy Graubert, MD. The Graubert laboratorystudies the molecular basis of human myeloid leukemias. The candidate should be well-trained in basic molecular biology, cell biology, and biochemical techniques with expertise in hematopoiesis, genetics, and mouse models of human leukemia.
Marcela Maus, MD, PhD. The Maus laboratory focuses on human T cell activation and costimulation, generating and testing novel forms of genetically modified and re-targeted human T cells with the goal of developing and understanding new forms of cellular immunotherapy. We generate and study native and chimeric antigen receptors (or CARs). Expertise in molecular biology techniques, cellular immunology including flow cytometry, and animal modeling is desired.
Interested candidates should e-mail a brief cover letter and CV to:
Ivona Olszak (firstname.lastname@example.org)
Massachusetts General Hospital Cancer Center/Harvard Medical School
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