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Center for Engineering in Medicine
Recent news and upcoming events from the Center for Engineering in Medicine at Massachusetts General Hospital.
August 14, 2017
A patent was issued to Professor Martin Yarmush, entitled, "In Vitro Model of Macrosteatotic (Fatty) Liver” (US patent number 9,709,554). The invention describes the development of an in vitro model for macrosteatosis which can be used for identifying compounds for defatting and functional recovery of fatty hepatocytes.
July 31, 2017
Professors Mehmet Toner, Korkut Uygun, and Martin Yarmush have been awarded a 4-year, $1,539,000 research grant from the NIH for a project entitled, "High subzero preservation of liver for transplantation”. The project proposes a method for preserving mammalian organs which employs hibernating and freeze-tolerant strategies from nature, that are further augmented using bioengineering principles.
May 27, 2017
A new book edited by Professors Martin Yarmush and Alexander Golberg (Tel Aviv University) was published on 27th May 2017. It is titled “Bioengineering In Wound Healing A Systems Approach” and part of series in “Frontiers in Nanobiomedical Research” published by World Scientific Publishing Co Pte Ltd. More details here.
Third Annual BioEngineering 2017 Conference took place in Boston on March 16th and 17th with significant contribution from CEM. The theme for the conference this year was BioMEMS, 3D-BioPrinting & Synthetic Biology. CEM Faculty Shannon Stott, Mehmet Toner, Martin Yarmush, and Daniel Irimia gave keynote presentations and Berk Usta was an invited speakers.
Martin Yarmush opened the conference by his talk entitled “Hills and Valleys in the Landscape of Cell-Based BioMEMS and Tissue Engineering”, where he gave an overview of recent advances in the fields of cellular BioMEMS and tissue engineering. He emphasized important considerations for the field that may help spur future meaningful advancements.
Mehmet Toner’s talk titled “Microfluidics to Isolate Single and Clusters of Rare Circulating Tumor Cells to Manage Cancer Patients”, gave an overview of microfluidic systems developed specifically to isolate extremely rare circulating tumor cells. He introduced more recently designed CTC-iChip system based on the inertial focusing strategy, which allows positioning of cells in a near-single file line, so that they can be precisely deflected using minimal magnetic force.
Shannon Stott’s talk was titled “Exploring the Biophysics of Circulating Tumor Cell Clusters Using Microfluidics”, where she presented their studies on larger aggregates or clusters of tumor cells that are found in most aggressive cancers in minute amounts, but once detected could be used as “liquid biopsy” in cancer.
Daniel Irimia’s talk was titled “Accurate Sepsis Diagnostic in a Microfluidic Assay” where he introduced a novel microfluidic platform which could be used to identify sepsis in patients with extremely high precision, by measuring the motility phenotype of neutrophils, directly in a droplet of blood.
In addition, CEM alumni Jeff Morgan, Jungwoo Lee, Albert Folch, Tania Konry also presented their work.
February 10, 2017
Professors Martin Yarmush and Mehmet Toner were among 84 new members and 22 foreign associates elected to the National Academy of Engineering (NAE). Election to the NAE is among the highest professional distinctions accorded to an engineer. Academy membership honors those who have made outstanding contributions to "engineering research, practice, or education, including, where appropriate, significant contributions to the engineering literature" and to "the pioneering of new and developing fields of technology, making major advancements in traditional fields of engineering, or developing/ implementing innovative approaches to engineering education." Individuals in the newly elected class will be formally inducted during a ceremony at the NAE’s annual meeting in Washington, D.C. on Oct. 8, 2017.
January 19, 2017
A patent was issued to Professor Martin Yarmush and colleagues from L’Oreal and Hurel Corp. entitled, "Immune System Modeling and Devices” (US patent number 9,535,056). The invention describes the development of an allergy-on-a-chip device which can be used to detect and classify chemicals that cause an immune reaction.
December 12, 2016
Professor Martin Yarmush, delivered a Keynote Presentation at the annual meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) held in San Diego, CA. The title of his presentation was "Multiscale Tissue Engineering: from Novel Microfabricated In Vivo Analogues to Organ Fabrication" September 22, 2016
Professors Berk Usta, Martin Yarmush and Alex Golberg (from Tel Aviv University), were awarded a 2-year $120,000 US-Israel BSF Grant to develop a nonchemical wound disinfection process using pulsed electric field technology.
A listing of upcoming events that the Center for Engineering in Medicine at Massachusetts General Hospital.
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