Faculty > Jose C. Florez.    
       

Jose C. Florez, M.D., Ph.D.

Selected Publications

1. Moore AF and Florez JC. Genetic susceptibility to type 2 diabetes and implications for antidiabetic therapy. Annu Rev Med 2008 (in press).
 
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2. Florez JC, Manning AK, Dupuis J, Gianniny L, Irenze K, McAteer J, Mirel DB, Fox CS, Cupples LA, Meigs JB. A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: Replication and integration with other genome-wide datasets. Diabetes 2007;56: 3063 -3074.

3. The Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University and Novartis Institutes for BioMedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316:1331-1336.

4. Florez JC, Jablonski KA, Sun MW, Kahn SE, Shamoon H, Hamman RF, Knowler WC, Nathan DM, Altshuler D for the Diabetes Prevention Program Research Group. Effects of the type 2 diabetes-associated missense polymorphism PPARG P12A on progression to diabetes and response to troglitazone. J Clin Endocrinol Metab 2007;92:1502-1509.

5. Florez JC, Jablonski KA, Kahn SE, Franks PW, Dabelea D, Hamman RF, Knowler WC, Nathan DM, Altshuler D for the Diabetes Prevention Program Research Group. The diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program. Diabetes 2007;56:531-536.

6. Florez JC. The new type 2 diabetes gene TCF7L2. Curr Opin Clin Nutr Metab Care 2007;10:391-396.

7. Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PIW, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D, for the Diabetes Prevention Program Research Group: TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 2006;355:241-250.

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