Photo of Mark Steven Vrahas, MD

Mark Steven Vrahas, MD

  • Robert W. Lovett Professor of Orthopedic Surgery, Harvard Medical School
  • Vice-Chair for Population Health & OR Operations
  • Chief, Partners Orthopaedic Trauma Service


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Dr. Vrahas is a leading specialist who treats orthopaedic injuries of the hip & pelvis. As Chief of the Partners Orthopaedic Trauma Service, Dr. Vrahas has created a care delivery system, ensuring patients receive optimal care during their recovery.



Centers & Specialties

MassGeneral Hospital for Children

Trauma Center

Clinical Interests
  • Orthopedic trauma
  • Pelvic and acetabular fractures
  • Total hip replacement
  • Hip fractures
  • Nonunions of fractures
  • Osteomyelitis
  • Post traumatic reconstruction
  • Hip reconstruction/osteotomy
  • Arthritis
Medical Education
  • MD, University of Pittsburgh School of Medicine
  • Residency, University of Pittsburgh Medical Center
  • Fellowship, Sunnybrook & Women's College Health Sciences Centre|Fellowship, University of Iowa
Board Certifications
  • Orthopaedic Surgery
  • Boston: Massachusetts General Hospital
Insurances Accepted
  • MassHealth
  • Medicare
  • Medicare - ACD
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - New York
  • OSW - Rhode Island
  • Railroad Medicare
  • Railroad Medicare - ACD
  • Senior Whole Health
  • TriCare
Patient Age Group
Pediatric and Adult

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Dr. Vrahas was recruited to Boston in 1999 to develop an orthopaedic trauma program across Partners, which consists of Massachusetts General Hospital and Brigham and Women's Hospital. Dr. Vrahas' goals were to:

  1. Meet and exceed the standards for clinical orthopaedic trauma care provided by major trauma centers around the county,
  2. Develop an educational program for residents and fellows, and
  3. Develop clinical and basic research programs

These efforts over Dr. Vrahas' tenure have led to a Trauma Program that is now nationally and internationally recognized for excellence.

Dr. Vrahas' clinical interests include pelvic and acetabular (hip socket) fracture fixation, fracture non union, and hip surgery. He is an internationally renowned pelvic and acetabular surgeon, who lectures frequently about this topic.

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Research & Publications

Research Summary

Dr. Vrahas is dedicated to understanding the human biological and clinical processes associated with traumatic orthopaedic injuries, and educating his peers and students. Toward this end, he has published prolifically on relevant topics like the cellular response to injury, the efficacy of certain orthopaedic implants and using gene therapy for fracture healing. Dr. Vrahas is very proud to have served as mentor to dozens of young orthopaedic residents and fellows interested in orthopaedics trauma surgery and research.


Select publications:

Thomas SH, Arthur AO, Howard Z, Shear ML, Kadzielski JL, Vrahas MS. Helicopter emergency medical services crew administration of antibiotics for open fractures. Air Med J. 2013;2:74-79.

Okike K, Lee OC, Makanji H, Harris MB, Vrahas MS. Factors associated with the decision for operative versus nonoperative treatment of displaced proximal humerus fractures in the elderly. Injury. 2013;4:448-455.

Menendez ME, Neuhaus V, Bot AG, Vrahas MS, Ring D. Do psychiatric comorbidities influence inpatient death, adverse events, and discharge after lower extremity fractures?. Clin Orthop. 2013;10:3336-3348.

Liu W, Zhou D, Liu F, Weaver MJ, Vrahas MS. Mechanical complications of intertrochanteric hip fractures treated with trochanteric femoral nails. J Trauma Acute Care Surg. 2013;2:304-310.

Ferreira E, Porter RM, Wehling N, O'Sullivan RP, Liu F, Boskey A, Estok DM, Harris MB, Vrahas MS, Evans CH, Wells JW. Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. J Biol Chem. 2013;41:29494-29505.

Fayaz HC, Haas N, Kellam J, Bavonratanavech S, Parvizi J, Dyer G, Pohlemann T, Jerosch J, Prommersberger KJ, Pape HC, Smith M, Vrahas M, Perka C, Siebenrock K, Elhassan B, Moran C, Jupiter JB. Improvement of research quality in the fields of orthopaedics and trauma: A global perspective. Int Orthop. 2013;7:1205-1212.

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News & Events


Orthopaedic Associates
55 Fruit Street
Yawkey Center for Outpatient Care, Suite 3C
Boston MA, 02114-2696
Phone 1: 617-726-9111
Fax: 617-726-8214

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