Find a Doctor

Physician Photo

Samuel M. (Sam) Moskowitz, MD

Director, MGH CF Center and Pediatric CF Clinical Program

Associate Chief, MGH Pediatric Pulmonary Unit

Staff Physician

Department of Pediatrics


  • MassGeneral Hospital for Children
  • Pulmonary
  • Cystic Fibrosis
  • Asthma
Clinical Interests
Cystic fibrosis
Airway hyperresponsiveness
Artificial ventilation
Chronic cough
Congenital pulmonary disease
Diagnostic problems in infants
Boston: Massachusetts General Hospital
Braintree: Blue Hills Medical Center
Medical Education
MD, Harvard Medical School
Residency, Seattle Children's Hospital
Fellowship, Children's Regional Medical Center
Board Certifications
Pediatric Pulmonology, American Board of Pediatrics
Patient Age Group
Accepting New Patients


Dr. Sam Moskowitz received his AB from Princeton Univ. in 1986 and MD magna cum laude in 1994 from Harvard Medical School. His research interests lie in the investigation of pediatric lung disease, particularly in cystic fibrosis and lung infection by Pseudomonas. He has held academic and clinical positions at Univ. of Washington School of Medicine and Seattle Children's Hospital, and is currently affiliated with MassGeneral Hospital for Children and Harvard Medical School.


View my most recent publications at PubMed

1: Moskowitz SM, Brannon MK, Dasgupta N, Pier M, Sgambati N, Miller AK, Selgrade SE, Miller SI, Denton M, Conway SP, Johansen HK, H?iby N. PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treatedcystic fibrosis patients. Antimicrob Agents Chemother. 2012 Feb;56(2):1019-30.2: Miller AK, Brannon MK, Stevens L, Johansen HK, Selgrade SE, Miller SI, H?ibyN, Moskowitz SM. PhoQ mutations promote lipid A modification and polymyxinresistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosispatients. Antimicrob Agents Chemother. 2011 Dec;55(12):5761-9.3: Moskowitz SM, Emerson JC, McNamara S, Shell RD, Orenstein DM, Rosenbluth D,Katz MF, Ahrens R, Hornick D, Joseph PM, Gibson RL, Aitken ML, Benton WW, BurnsJL. Randomized trial of biofilm testing to select antibiotics for cystic fibrosisairway infection. Pediatr Pulmonol. 2011 Feb;46(2):184-92.4: Moskowitz SM, Garber E, Chen Y, Clock SA, Tabibi S, Miller AK, Doctor M,Saiman L. Colistin susceptibility testing: evaluation of reliability for cysticfibrosis isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophilia. JAntimicrob Chemother. 2010 Jul;65(7):1416-23.5: Johansen HK, Moskowitz SM, Ciofu O, Pressler T, H?iby N. Spread of colistinresistant non-mucoid Pseudomonas aeruginosa among chronically infected Danishcystic fibrosis patients. J Cyst Fibros. 2008 Sep;7(5):391-7.6: Moskowitz SM, Ernst RK, Miller SI. PmrAB, a two-component regulatory systemof Pseudomonas aeruginosa that modulates resistance to cationic antimicrobialpeptides and addition of aminoarabinose to lipid A. J Bacteriol. 2004Jan;186(2):575-9.

Research of Sam Moskowitz, MD

The Moskowitz research program at MGHfC focuses on chronic airway infection and host-pathogen interactions in cystic fibrosis (CF), encompassing the fields of microbiology, biochemistry, immunology, epithelial biology, bacterial and eukaryotic genetics, and pulmonary medicine.

Breakthrough cystic fibrosis drug gives hope, transforms lives

Praised by experts as a breakthrough for patients with a particular form of cystic fibrosis, ivacaftor was approved by the United States Food and Drug Administration (FDA) in January 2012 and is the first of its kind to treat the underlying defects of the disease, rather than manage its symptoms.

Pediatric Pulmonary
275 Cambridge Street
Boston, MA 02114-3108

Phone: 617-726-8707
Phone 2: 617-643-7232
Fax: 617-724-2803

Pediatric Pulmonary
275 Cambridge Street
Boston, MA 02114-3108

Phone: 617-726-8707
Phone 2: 617-643-7232
Fax: 617-724-2803


Explore our community locations

You can see MassGeneral for Children specialists in more than a dozen locations throughout Eastern Massachusetts and Southern New Hampshire.


Make an appointment

Contact MassGeneral Hospital for Children to schedule an appointment with one of our specialists.


Refer a patient

Referring a patient to MassGeneral Hospital for Children is easy.