Dr. Mitchell's research is concerned with factors which promote optimal bone growth and mineralization during childhood and adolescence, with a goal of preventing osteoporosis and fractures in adults. She is currently investigating bone accrual and microarchitecture in children with type 1 diabetes, a condition known to increase the risk of bone fragility. Her goal is to better understand why patients with diabetes are at increased risk of fracture in order to be able to design and test therapies to strengthen bones in this population.
Publications McCormack S., Mitchell D.M., Woo M., Levitsky L.L, Ross D.S., and Misra M. 2009 Radioactive iodine for hyperthyroidism in children and adolescents: referral rate and response to treatment. Clin Endocrinol. 71, 884-91.
Mitchell, D.M. and Juppner, H. 2010. Regulation of calcium homeostasis and bone metabolism in the fetus and neonate. Curr. Opin. Endocrinol. Diabetes Obes 17, 25-30.
Mitchell D.M., Regan S., Cooley M.R., Lauter K.B., Vrla M.C., Becker C.B., Burnett-Bowie S.M., and Mannstadt M. 2012. Long-term follow-up of patients with hypoparathyroidism. Jnl Clin Endocrinol Metab 97, 4507-14.
Mitchell D.M.,Henao M.P., Finkelstein J.S., and Burnett-Bowie S.M. 2012. Prevalence and predictors of vitamin D deficiency in healthy adults. Endocrine Practice 18, 914-23.
McCormack S., Mitchell D.M., Woo M., Levitsky L.L, Ross D.S., and Misra M. 2009 Radioactive iodine for hyperthyroidism in children and adolescents: referral rate and response to treatment. Clin Endocrinol. 71, 884-91.
Childhood is a critical time for bone health. Approximately 90% of peak bone mass is acquired by age 18, with about 50% of this acquired during the pubertal growth spurt. As a pediatrician, my research goal is to better understand the factors which impact bone growth and mineralization during this important window in order to maximize long-term bone health.
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