Browse by Medical Category
Translocation Down syndrome happens when an extra copy of chromosome 21 is attached to another chromosome. This is then present in all cells of the body.
In Translocation Down syndrome, an extra copy of chromosome 21 is attached to a different chromosome. For example, when an extra chromosome 21 is attached to chromosome 14, it looks like the picture below.
Translocation Down syndrome can happen one of two ways:
If the extra copy of chromosome 21 is inherited from a parent in the egg or sperm, it means that the parents “carry” this type of Down syndrome. These parents are said to have a “balanced translocation.” Balanced translocation happens when the correct amount of genetic material is present in the wrong location.
People with balanced translocations do not have any features of Down Syndrome. However, it is possible that they may have trouble getting pregnant.
Yes. Translocation Down Syndrome is the only type of Down Syndrome that can be passed down from a parent who does not have features of Down Syndrome.
Back to Top