Harvard Catalyst Announcements from the MassGeneral Hospital for Children Research Council.
Featured News and Announcements
New York Stem Cell Foundation and eagle-i Network Co-Develop iPS Cell Database Induced Pluripotent Stem Cells (iPS) hold enormous potential to unravel the mechanisms of human illness and to develop new therapeutics. Until now, investigators have not had an easily searchable database to find and share these important resources. The New York Stem Cell Foundation and eagle-i Network recently co-developed an iPS cell database to help ease the major obstacle to the implementation of iPS technology.
Blast Trauma to the Ears: New video on Boston Marathon bombing hearing study New Harvard Catalyst video features interviews with the researchers behind the three-year study, and highlights the role of the IRB Cede Review form in expending this multisite endeavor.
IRB Reliance: A New Model for Accelerating Translational Science The National Center for Advancing Translational Sciences (NCATS) feature story on the IRB review process, highlighting Harvard Catalyst's IRB Reliance Agreement that helped facilitate the hearing study on Boston Marathon bombing victims.
Spotlight: Advanced Curriculum Compendium (ACC) The Harvard Catalyst Advanced Curriculum Compendium (ACC) helps investigators stay current by opening the doors to opportunities at Harvard-affiliated institutions and academic healthcare centers. Read how the Compendium can help you discover options for continuing education in core competencies fundamental to successful clinical investigation.
Harvard Catalyst Education & Courses
Leadership Strategies for the Researcher, October 16-17, 2014 – applications due July 31, 2014 Navigating a career in research can be challenging. In this two-day interactive course, learn how to develop programs and manage projects, negotiate effectively, hire and manage a workforce, and manage budgets and grants.
Introduction to Translational Medicine, September 29-October 1, 2014 –applications due August 1, 2014 This three-day survey course offers an introduction to the skills necessary to embark on a career in translational research, with a focus on the principles and practices of translational medicine as they apply to the development of a new drug (small molecules and/or biologics), device, or diagnostic.
Advanced Imaging: Imaging in Clinical/Translational Cardiovascular Research, September 16-18, 2014 – applications due August 8, 2014 This three-day course explores the available imaging technologies commonly used in cardiovascular research, and gives participants the opportunity to consider how they might use imaging in their own clinical or translational research.
Grant Review and Support Program (GRASP), October 20-22, 2014 – applications due August 14, 2014 As junior investigators make their way through their first year of NIH career development awards toward a R01 grant, this Harvard Catalyst program offers firsthand guidance and preparation each step of the way. GRASP provides workshops, tools, and resources that support investigators throughout this important career shift.
Introduction to Network Medicine, November 3-5, 2014 – application due August 14, 2014 When network medicine is integrated into biomedical research, it has the potential to transform investigations of disease etiology, diagnosis, and treatment. This three-day course is an introduction to the developing field of network science in biology and medicine.
Certificate in Applied Biostatistics September 20-May 30, 2015 – applications due August 15, 2014 This course offers a comprehensive introduction to biostatistics in medical research, and includes a review of the most common techniques in the field, as well as the manner in which these techniques are applied in standard statistical software. At the conclusion of the course, participants will be able to choose an appropriate study design, calculate the sample size needed to complete a study, analyze the collected data, and communicate the results from their experiment.
Introduction to Clinical Investigation, October 6-10, 2014 – applications due September 5, 2014 Considering a career in clinical research? Watch this video to learn more about Harvard Catalyst's popular five-day course which offers an engaging introduction to navigating a career in this exciting and growing field. Through a mix of lectures and workshops led by faculty leaders in clinical research, course participants will gain an overview of the translational research spectrum from T1 to T4. If you are looking for an introductory, working knowledge of the T1-T4 domains to determine the research area best suited to your career path, this is the course for you. See the Spotlight on this course.
Comparative Effectiveness, Cost-Benefit Analysis, and Implementation Research, November 3-5, 2014 – applications due September 12, 2014 In this course, advanced trainees and junior faculty will get an overview of T3/T4 research which focuses on the translation of findings from research in controlled environments to general clinical practice and population health.
Medical Device Development October 28-29, 2014 – applications due September 12, 2014 Do you have an idea for a medical device, thoughts on how to improve a current device, or need insight on how to move forward with your idea? This two-day course will cover the process of identifying novel technologies, navigating intellectual property and regulatory considerations, and planning and executing pre-clinical and clinical studies through licensing and commercialization.
Harvard Catalyst Events
RPDR Clinic for Health Disparities Research, September 4, 2014 – applications due August 11, 2014 The Harvard Catalyst Health Disparities Research Program, together with the Biomedical Informatics Program, will co-host a clinic for investigators interested in using the Research Patient Data Registry (RPDR) for research on health disparities. Participants will receive an overview of RPDR, a tutorial on how to conduct queries, and personalized feedback and assistance on submitting queries specific to their population and research question of interest. Attendance is limited. A faculty committee will base their selection on query feasibility, and the project's relevance to the field of health disparities research. Please review the eligibility criteria and apply by August 11.
Mental Health and the Developing Brain in the Second Decade of Life: Research Challenges and Opportunities – October 6, 2013 The second decade of life is one of tremendous physiological and psychological changes. This year’s symposium will bring together outstanding speakers from across the nation to participate in a dialog with Harvard’s Child Health Research community, and spur formation of new collaborations, which will hopefully lead to groundbreaking research aimed at enhancing mental health in late childhood, adolescence, and across the life course. Session topics include mood dysregulation, youth suicide, violence, and concussion and the developing brain, with keynotes from Ronald C. Kessler, PhD, and Jay N. Geidd, MD. October 6, 9:00am-5:30pm, Joseph B. Martin Conference Center, Harvard Medical School (HMS). Please visit the website for more information and to register.
Harvard Catalyst Funding
Harvard Catalyst Resources
New Video Series for Prospective Participants The Research Subject Advocacy Program has developed a series of brief informational videos for those considering research participation. The series discusses the importance of clinical research, risks, and benefits of participating, and participant rights and protections. Watch the series on the Harvard Catalyst website.
ClinicalTrials.gov: What is it? How do I register? Federal law and journal publication standards require that investigators register their clinical studies in a publicly accessible database. It's a complex topic, but don't worry, Harvard Catalyst has resources and guidance available to help you understand how the regulations impact you and your research, and how to register your study on clinicaltrials.gov. If you're a research administrator looking for tools to help present this information to your investigators, we've got that too.
Research Subject Bill of Rights & Brochure Available in 15 Languages Looking for materials in translation to support conversations with non-native English speakers? The Research Subject Advocacy Program has translated the Research Subject Bill of Rights and informational brochure "Should I Be A Research Subject?" into 15 languages: Albanian, Arabic, Cape Verdean, French, Greek, Haitian Creole, Italian, Khmer/Cambodian, Korean, Polish, Portuguese, Russian, Spanish, Traditional Chinese, and Vietnamese.
New Informational Brochures for Research and Prospective Research Subjects Available Looking for materials to support conversations with research and prospective research subjects? The Massachusetts Research Subject Advocacy Group has developed informational brochures to provide prospective research subjects with basic information and important issues to consider on genetic research, social and behavioral research, MRI, PET, and CT Scans, as well as blood draws. Please see the website to preview and download these brochures.
Additional Courses, Events, Funding, and Resources
Master of Medical Sciences (MMSc) in Biomedical Informatics at Harvard Medical School – applications due August 15, 2014 The Master of Medical Sciences (MMSc) in Biomedical Informatics is a two-year post-doctoral degree program that consists of course work and mentored research with faculty at the Center for Biomedical Informatics. The program is open to federally-funded post-doctoral trainees at Harvard and its affiliated hospitals. Courses can also be taken without being enrolled as a degree-seeking student. Applications for fall 2014 will be accepted until August 15. Please contact Katherine Flannery, MMSc program manager, for complete information about tuition costs and admission procedures.
Understanding Risk-Based Monitoring – Pros, Cons, & the Bottom Line – August 7, 2014 The FDA has joined the growing consensus in the pharmaceutical industry that risk-based approaches to monitoring will help ensure subject protection and overall study quality. Please join us to explore the implications and future of risk-based monitoring to your clinical programs. August 7, 8:00-10:00am, MassBio, 300 Technology Square, eighth floor, Cambridge, MA. Registration is required.
Evergrande Center Symposium: Immunity and Inflammation in Disease and Tissue – August 11, 2014 The Evergrande Center for Immunologic Diseases at Harvard Medical School and Brigham & Women’s Hospital seeks to advance biomedical research and education with a focus on understanding the basis and role of inflammation in multiple human diseases. Speakers for the first Evergrande Center Symposium on immunity and inflammation in health and disease are: Richard Flavell, Yale University; Diane Mathis, Harvard Medical School; Ruslan Medzhitov, Yale University; Fiona Powrie, University of Oxford; Larry Steinman, Stanford University; and Bruce Walker, Ragon Institute. August 11, 9:00am-12:30pm, Joseph B. Martin Conference Center, Boston, MA. Please see the website for more information.
Conference: Post-Trial Responsibilities: Ethics and Implementation – September 18, 2014 Law, policy, and guidance are vague, sometimes conflicting, and generally lacking in concrete solutions for questions regarding post-trial responsibilities. The issues are complex and demand thoughtful discourse to move the clinical trial enterprise toward meaningful solutions. The conference will include a diverse set of global stakeholders who will address and develop some consensus around various topics, such as the range of perspectives on post-trial access, implications of the 2013 Declaration of Helsinki revisions, and potential scenarios and solutions for post-trial access to medicines. September 18, 7:30am-5:30pm, Harvard Law School, Wasserstein, Cambridge, MA. For more information and to register, please visit the website.
Conference: Integrative Approaches to Understand Allelic Function – November 20-21, 2014 The 2014 PQG Conference: Integrative Approaches to Understand Allelic Function will examine the use of evolutionary functional genomics, statistical genetics, and integrative approaches to understand the function of rare and common human alleles, as well as discuss the interdisciplinary challenges of data analysis involved. Participants are encouraged to submit abstracts for the poster session. Three abstracts will be selected to be presented as 15-minute platform talks. November 20-21, Joseph B. Martin Conference, HMS, Boston, MA. Please see the website for complete information and to register.
Feasibility projects and scholar awards for HIV/AIDS research – applications due August 5, 2014 The Harvard University Center for AIDS Research (HU CFAR) is now accepting proposals for HIV/AIDS research awards beginning October 1, 2014. Proposals will be accepted for feasibility projects and scholar awards for research in one or more of the six HU CFAR scientific research programs: behavioral and social sciences, clinical epidemiology and outcomes research, international research, pathogenesis, therapeutics, and vaccine. Complete information can be found on the website.
Joslin Diabetes Center Pilot Feasibility Grants – letters of intent due October 3, 2014 The Diabetes Research Center (DRC)/Joslin Diabetes Center is accepting applications for pilot feasibility grants for research projects to study diabetes and its complications from basic, translational, or clinical perspectives. Open to Harvard affiliates, two proposals will be awarded $50,000/year for two years. Please see the website for complete details on eligibility and how to apply.
Learn how researchers at MassGeneral Hospital for Children are finding new treatments that advance pediatric care.
Learn how the Research Council supports and enhances research within MassGeneral Hospital for Children as well as new initiatives and directions for pediatric research at Mass General.