Research Council Announcements: Harvard Catalyst

Harvard Catalyst Announcements from the MassGeneral Hospital for Children Research Council.

Harvard Catalyst

Featured News and Announcements

Pilot Funding Opportunity: Up to $75,000 for Proposals that Address Child/Adolescent Mental Health – applications due January 6, 2015
Attendees at the forthcoming Child Health Symposium (see below) are eligible to apply for a new pilot funding opportunity: Addressing Mental Health in the Second Decade of Life Through Translational Lifecourse Research. Proposals are welcome in the following two research priority areas of child/adolescent health: (1) mood dysregulation and its consequences, including suicide, and (2) interpersonal violence. The anticipated funding start date is May 2015. If you have questions, please email us. Please note: To be eligible for this award, the principal investigator or a co-investigator must attend Harvard Catalyst’s Child Health Symposium on October 6. See the website for symposium details and to register by September 29.

Harvard Catalyst Education & Courses

A Practical Guide to Biobanking for Biomarker and Personalized Medicine Research – October 1, 2014
The wide array of bio-specimens, including serum, plasma, and DNA, maintained in biobanks have become an important resource in genomic research, clinical translational research, and in the advancement of personalized medicine. This course will provide an introduction to the use of biorepositories for clinical research, a practical guide to banking, accessing, and using samples and phenotypic data, and an overview of relevant human subjects issues for investigators and staff at all levels interested in the utility of biorepositories for their research.  It will include a user-friendly practical introduction to the Partners HealthCare Biobank, a large-scale repository of biospecimens linked to the Partners electronic medical record that provides a powerful, low-cost resource for clinical and translational research. Please contact Jillian Tonelli with any questions.

Harvard Catalyst Events

Mental Health and the Developing Brain in the Second Decade of Life: Research Challenges and Opportunities – register by September 29, 2014 
The second decade of life is one of tremendous physiological and psychological changes. This year’s symposium will bring together outstanding speakers from across the nation to participate in a dialog with Harvard’s Child Health Research community, and spur formation of new collaborations, which will hopefully lead to groundbreaking research aimed at enhancing mental health in late childhood, adolescence, and across the life course. Session topics include mood dysregulation, youth suicide, violence, and concussion and the developing brain, with keynotes from Ronald C. Kessler, PhD, and Jay N. Geidd, MD. October 6, 9:00am-5:30pm, Joseph B. Martin Conference Center, Harvard Medical School (HMS). Please visit the website for more information and to register.

A Conversation with the Health and Human Services Office of the Inspector General – September 30, 2014
Come hear about the work of the Office of the Inspector General (OIG), its role in the Department of Health and Human Services, and some of its current, past, and future projects.  Joyce Greenleaf, MBA, regional inspector general, and Jessica Fargnoli, MPH, program analyst, will speak. Registration is required, and seating is limited. September 30, 4:00-5:00pm, Smith Building, Smith Conference Room 308/309, Dana-Farber Cancer Institute.

Biostatistics Seminar:  Survival Analysis with Uncertain Endpoints Using an Internal Validation Subsample – October 8, 2014 
Sharon Xie, PhD, associate professor of biostatistics in the Department of Biostatistics and Epidemiology at the Perelman School of Medicine University of Pennsylvania, will present at the Harvard Catalyst Biostatistics Program seminar, co-sponsored by the Massachusetts Alzheimer’s Disease Research Center at Massachusetts General Hospital (MGH) on October 8, 12:30-1:30pm, Harvard School of Public Health (HSPH), Building 2, fourth floor, room 426.

Harvard Catalyst Funding

Harvard Catalyst Resources

New Video Series for Prospective Participants The Research Subject Advocacy Program has developed a series of brief informational videos for those considering research participation. The series discusses the importance of clinical research, risks, and benefits of participating, and participant rights and protections. Watch the series on the Harvard Catalyst website. What is it? How do I register? Federal law and journal publication standards require that investigators register their clinical studies in a publicly accessible database. It's a complex topic, but don't worry, Harvard Catalyst has resources and guidance available to help you understand how the regulations impact you and your research, and how to register your study on If you're a research administrator looking for tools to help present this information to your investigators, we've got that too.

Research Subject Bill of Rights & Brochure Available in 15 Languages
Looking for materials in translation to support conversations with non-native English speakers? The Research Subject Advocacy Program has translated the Research Subject Bill of Rights and informational brochure "Should I Be A Research Subject?" into 15 languages: Albanian, Arabic, Cape Verdean, French, Greek, Haitian Creole, Italian, Khmer/Cambodian, Korean, Polish, Portuguese, Russian, Spanish, Traditional Chinese, and Vietnamese.

New Informational Brochures for Research and Prospective Research Subjects Available
Looking for materials to support conversations with research and prospective research subjects? The Massachusetts Research Subject Advocacy Group has developed informational brochures to provide prospective research subjects with basic information and important issues to consider on genetic research, social and behavioral research, MRI, PET, and CT Scans, as well as blood draws. Please see the website to preview and download these brochures.

Additional Courses, Events, Funding, and Resources



Comparative Effectiveness and Cost-Effectiveness – September 23, 2014
The Patient-Centered Outcomes seminar series, sponsored by the Brigham and Women's Hospital (BWH) BRI Patient-Centered Comparative Effectiveness Research Center (PCERC), will bring together patient-centered outcomes research (PCOR) and comparative effectiveness researchers (CER) to discuss research findings, methods, and policy related to CER and PCOR. The seminar will feature Milton C. Weinstein, PhD, Henry J. Kaiser Professor of Health Policy and Management at the Department of Health Policy and Management and the Department of Biostatistics at Harvard School of Public Health. September 23, 12:00-1:30pm, Shapiro Board Room, BWH. Please register online for this event.

Women in Medicine and Science Symposium – September 29, 2014
The 2014 Women in Medicine and Science Symposium will highlight the collaborations and achievements of women faculty and trainees at Brigham and Women’s Healthcare across different disciplines, including basic, clinical innovation, and translational research projects, with the goal of building community. Terrie Inder, MD, MBChB, chair of theDepartment of Pediatric and Newborn Medicine, BWH, is the 2014 keynote speaker. September 29, 2:30-6:00pm, Bornstein Amphitheatre, BWH. For more information and to register, please see the website.

MassCONNECT Companies Present: Spotlight on Science – September 30, 2014 
MassCONNECT is MassBio's program that connects entrepreneurs and founders with seasoned life sciences professionals to catalyze and commercialize innovation. Each year 12 emerging companies graduate from the program. Hear graduates present the cutting-edge science that led them to start this exciting journey. September 30, 8:00-10:00am, MassBio, 300 Technology Square, eighth floor, Cambridge. Registration is required.

Seminar: Pursuing Placebo Effects – October 2, 2014
Ted J. Kaptchuk, professor of medicine at HMS and director of the Program in Placebo Studies and Therapeutic Encounter at the Beth Israel Deaconess Medical Center will speak on this topic at the Integrative Medicine Research Seminar. October 2, 4:00-5:00pm, 70 Francis Street, Shapiro Breakout Room, Brigham and Women's Hospital.

Autism Consortium 2014 Research Symposium – October 21, 2014
The annual symposium brings together over 400 scientists, clinicians, advocates, and families to hear about new innovations and collaborations in autism research and clinical care. The day will include a Family Resource and Research Fair, a poster session, panel talks, and plenary talks by Matthew State, MD, PhD, Rudolf Jaenisch, MD, and Sarah Spence, MD, PhD. October 21, 8:00am-3:00pm, Joseph B. Martin Conference Center, HMS. For complete information and registration, please visit the website.

Conference: Addressing Irreproducibility in Target Validation – October 23, 2014
This one-day conference addresses a critical and timely topic in preclinical drug discovery which was succinctly stated in a recent article by Drs. Collins and Tabak (NIH): "A growing chorus of concern, from scientists and laypeople, contends that the complex system for ensuring the reproducibility of biomedical research is failing and is in need of restructuring." (Nature 505, 612–613,30 January 2014). The conference includes a series of talks and panels by industry, academic and government scientists, as well as editors from leading journals to lend perspective and brainstorm practical solutions. See the website for more information and to register.

Boston Children’s Hospital’s Global Pediatric Innovation Summit + Awards 2014 – October 30-31, 2014
Taking on Tomorrow provides an engaging forum to build partnerships, accelerate innovations, and help reshape the future of pediatric medicine. The dynamic and comprehensive agenda gathers innovators, thought leaders, investors and more from across the globe to examine clinical, informatics and business opportunities in pediatric innovation. Taking on Tomorrow will also recognize pediatric innovators with two awards: the Lifetime Impact Award and the Rising Star Award. October 30-31, Seaport World Trade Center, Boston. For program details, award nomination information, and to register, visit Taking on Tomorrow.

Conference: Integrative Approaches to Understand Allelic Function – November 20-21, 2014
The 2014 PQG Conference: Integrative Approaches to Understand Allelic Function will examine the use of evolutionary functional genomics, statistical genetics, and integrative approaches to understand the function of rare and common human alleles, as well as discuss the interdisciplinary challenges of data analysis involved. Participants are encouraged to submit abstracts for the poster session. Three abstracts will be selected to be presented as 15-minute platform talks. November 20-21, Joseph B. Martin Conference, HMS, Boston, MA. Please see the website for complete information and to register.


Health Acceleration Challenge – applications due September 29, 2014
Harvard Business School (HBS) and HMS are seeking proven innovations for US healthcare delivery that are ready to scale. Challenge finalists will share $150,000 in prize money, community feedback on our open application platform, and have access to senior healthcare leaders at our invite-only conference in April 2015. For examples of the types of innovations we're looking for and more information on the challenge, please visit the website. Applications due by September 29.

Joslin Diabetes Center Pilot Feasibility Grants – letters of intent due October 3, 2014
The Diabetes Research Center (DRC)/Joslin Diabetes Center is accepting applications for pilot feasibility grants for research projects to study diabetes and its complications from basic, translational, or clinical perspectives. Open to Harvard affiliates, two proposals will be awarded $50,000/year for two years. Please see the website for complete details on eligibility and how to apply.

Up to $500,000 for Innovative Approaches to Research – applications due October 3, 2014
The Falk Medical Research Trust was established to support research that leads directly to the development of treatments and cures for diseases for which there are no effective treatments or cures today. The Catalyst Research Program has been created to provide seed funding to help investigators and their institutions lay the foundation for successful application to the Transformational Research Program in 2015 and beyond. This program will provide one year of seed funding to enable planning and development of projects, teams, tools, techniques, and the management infrastructure necessary to successfully compete for multi-year contracts in the Transformational Research Program. It is designed to support high-risk, high-reward projects that are tackling critical scientific and therapeutic roadblocks. If successful, these projects will open new avenues for treating and curing disease. The program is well-suited to projects that need to develop preliminary data necessary to support innovative study rationales. Applications may be submitted in any area of basic, preclinical, and/or clinical research with clear, achievable milestones and deliverables. Please review the details to apply.



What will we discover next?

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The Research Council at MassGeneral Hospital for Children

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