Research Council Newsletter Volume 5, Issue 2

Announcements from the MassGeneral Hospital for Children Research Council, including research of Allan Goldstein, MD, Director of the Pediatric Neurogastroenterology Program; Eric C. Liao, MD, PhD, Assistant Professor of Surgery, Center for Regenerative Medicine, Harvard Stem Cell Institute; Mark Lindsay, MD, PhD, Lecturer on Pediatrics, Massachusetts General Hospital for Children and Harvard Medical School.

Feature Article: Hirschsprung Disease: exploring its causes, consequences, and novel treatments

Allan Goldstein, MD, Chief, Division of Pediatric Surgery, Surgical Director, Pediatric Neurogastroenterology Program, Associate Professor of Surgery, Harvard Medical School
Allan Goldstein, MD, Chief, Division of Pediatric Surgery, Surgical Director, Pediatric Neurogastroenterology Program, Associate Professor of Surgery, Harvard Medical School
The enteric nervous system (ENS) is an intricate network of neurons and glial cells present in the wall of the intestine and responsible for regulating critical functions of the gastrointestinal (GI) tract, including peristalsis, absorption, and secretion. This intestinal “brain” contains as many neuronal cells and subtypes as the central nervous system (CNS), and is capable of autonomous function without CNS input. Given its complexity and importance, it is not surprising that abnormalities of ENS structure and function lead to serious neurointestinal diseases, including Hirschsprung disease, irritable bowel syndrome, chronic intestinal pseudo-obstruction, slow transit constipation, and esophageal achalasia, which together affect a large number of individuals. My primary research focus is on understanding the causes and consequences of congenital enteric neuropathies and on developing innovative approaches to their treatment. Read more.

Research programs of faculty

Eric C. Liao, MD, PhD
Eric C. Liao, MD, PhD
Assistant Professor of Surgery, Center for Regenerative Medicine, Harvard Stem Cell Institute, Massachusetts General Hospital and Harvard Medical School Read more.


Mark Evan Lindsay, MD, PhD
Mark Evan Lindsay, MD, PhD
Lecturer on Pediatrics, Massachusetts General Hospital for Children and Harvard Medical School Read more.


Funding received by MGHfC faculty and fellows

Updates since April 2013. Learn more. (pdf).

Representation of MGHfC at national/international meetings and invited talks

Updates since April 2013 (excluding PAS 2013 presentations). Learn more. (pdf).

The Research Council at MassGeneral Hospital for Children

Learn how the Research Council supports and enhances research within MassGeneral Hospital for Children as well as new initiatives and directions for pediatric research at Mass General.

patient

What will we discover next?

Learn how researchers at MassGeneral Hospital for Children are finding new treatments that advance pediatric care.