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Deborah M. Mitchell, MD, Division of Pediatric Endocrinology, 'Bone Mineral Accrual and Microarchitecture in Youth with Type1 Diabetes'
The 2013 Research Pilot and Feasibility Award from the MGHfC Research Council allowed me to initiate a prospective study of bone mineral accrual in youth with type 1 diabetes. While adults with this disorder have low bone mineral density and a high risk of fracture, little is known about the precedents and pathophysiology of these complications. The preliminary data garnered over the course of this year will form the basis of more comprehensive research proposals to elucidate the mechanisms of fracture risk in patients with type 1 diabetes. This award has thus been crucial to my career development as an independent clinician-scientist.
Jolan Walter, MD, PhD, Division of Allergy/Immunology, "Dissecting mechanisms of central and peripheral dysregulation among patients with Rag deficiencies"
As a recipient of the 2012 Research Pilot and Feasibility Award from the MGHfC Research Council, I was funded to utilize new methods to investigate patients prone for autoimmune disorders in the setting of an immune deficiency. Specifically, I applied novel methods for characterization of B cell diversity among patients who are carriers of defective genes causing primary immunodeficiency. This pilot funding has complemented well my NIH K08 Career Award and gave impetus toward independent research.
Jamie Micco, PhD, Department of Psychiatry, "Development of cognitive biases in offspring at risk for anxiety disorders" "I received the Research Pilot and Feasibility Award from the MGHfC Research Council in July 2011. This award provided funding that was critical in supporting a small study of the development of cognitive biases in young children (ages 4-7) of parents with a history of anxiety disorders. Specifically, we examined whether children at risk for anxiety disorders are more likely to attend to potential threat and to interpret ambiguous situations as more threatening than children of parents with no history of anxiety or mood disorders. Funding from the MGHfC Research Council has allowed me to collect pilot data that will likely increase the competitiveness of larger grant applications on this topic. The award has thus helped place me on a career trajectory towards becoming an independent clinical researcher in the field of pediatric anxiety and mood disorders."
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