Join us for the Fifth Annual MassGeneral Hospital for Children Research Day on March 19th, 2013. Presented by the MGHfC Research Council, Research Day highlights recent accomplishments and advances from Mass General researchers, as well as from the broader pediatric research community.
Research Day 2013
Keynote Lecture: “Molecular Dissection of the new disorder Eosinophilic Esophagitis”
Stephanie Seminara, MD, Co-Director of the Reproductive Endocrine Associates, Massachusetts General Hospital, and Associate Professor of Medicine, Harvard Medical School
MGHfC Faculty Lectures
“Assessing the Safety and Efficacy of Inhaled Nitric Oxide in Cerebral Malaria”
Ryan Carroll, MD, Assistant in Pediatrics, MassGeneral Hospital for Children, Instructor in Pediatrics, Harvard Medical School
“The Preterm Infant's Behavioral Pain Response”
Kim Francis PhD, RN, PHCNS-BC, Neonatal Clinical Nurse Specialist for the Massachusetts General Hospital Obstetric Service, Clinical Instructor for the MGH Institute of Health Professions, Haley Nurse Fellow for Boston College and Brigham & Women’s Hospital
“Effects of Growth Hormone Augmentation on Visceral Fat and Metabolic Risk in HIV-infection”
Takara Stanley, MD, Assistant in Pediatrics, MassGeneral Hospital for Children, Assistant Professor in Pediatrics, Harvard Medical School
Poster Session Awardees
- Mridu Acharya (Mentor: Adam Lacy-Hulbert, PhD). αv integrins use autophagy machinery to modulate specific B cell immune responses
- Peter P. Moschovis, MD, MPH (Mentor: Patricia Hibberd, MD, PhD). Household air pollution and risk of childhood pneumonia death in low and middle income countries
- Deepak Palakshappa MD. Communication discrepancies between Pediatric Residents and Attendings; a supervision dilemma for residency training programs
Research Day 2012
Keynote Lecture: “Molecular Dissection of the new disorder Eosinophilic Esophagitis”
Marc Rothenberg, MD, PhD
Director of Allergy and Immunology at Cincinnati Children's Hospital Medical Center and the Cincinnati Center for Eosinophilic Disorders
MGHfC Faculty Lectures
“Immune Therapy in Type 1 Diabetes”
Nicole Sherry, MD
Instructor in Pediatrics, Harvard Medical School
Director, Diabetes Program, Pediatric Endocrinology, MassGeneral Hospital for Children
“Modulation of Mucosal Immunity by Intestinal Helminth Infection”
Haining Shi, DVM, PhD
Assistant Professor of Pediatrics, Harvard Medical School
Mucosal Immunology Laboratory, MassGeneral Hospital for Children
“Use of the Built Environment to Promote Physical Activity in Children”
Nicolas Oreskovic, MD, MPH
Instructor in Pediatrics, Harvard Medical School
Internal Medicine & Pediatrics, Massachusetts General Hospital
Center for Child & Adolescent Health Research and Policy
“Human RAG deficiency: not just immunodeficiency--Novel insights into mechanisms of immune dysregulation”
Jolan Walter, MD, PhD
Clinical Instructor in Pediatrics, Harvard Medical School
Physician, Pediatric Allergy/Immunology, MassGeneral Hospital for Children
Poster Session Awardees
- Elena Grant: Childhood Repair of Tetralogy of Fallot Leads to Long Term Hepatic Dysfunction
- Selvi Ramasamy: The TLE1 Tumor Suppressor Regulates Myc Induced Leukemogenesis
- Ana Sokovska/Christine Becker (co-first author presenters): Rab39a Links Caspase-1 Activation to Phagosome Acidification and Cellular Defense
Research Day 2011
Keynote Lecture: “Stem and Progenitor Cells in Neonatal Lung Injury and Repair”
Dr. Vivek Balasubramaniam
Univ. of Colorado – Director of Pediatric Heart Lung Center
MGHfC Faculty Lectures
Elahna Paul, MD, PhD
Instructor in Pediatrics, Harvard Medical School
Pediatric Nephrology, MassGeneral Hospital for Children
Jonathan Spector, MD
Instructor in Pediatrics, Harvard Medical School
Neonatology and Newborn Medicine, MassGeneral Hospital for Children
Ann-Christine Duhaime, MD
Nicholas T. Zervas Professor of Neurosurgery
Pediatric Neurosurgery, MassGeneral Hospital for Children
Poster Session Awardees
- Mauro Longoni. Diaphragmatic hernia: genetic dissection of a complex birth defect. Laboratory of Patricia K. Donahoe
- Jay Thiagarajah. Airway surfactant liquid depth imaged by surface laser reflectance microscopy. Laboratories of Jay Thiagarajah and A.S. Verkman.
- Orane Visvikis. Involvement of HLH-30/MiT transcription factors in intestinal epithelial immunity. Laboratory of Javier E. Irazoqui
Research Day 2010
Keynote Lecture: “Update on Obesity Research”
Lee Kaplan, MD, PhD
Director, MGH Weight Center
MGHfC Faculty Lectures
“Immunity to Cholera”
Jason Harris, MD
Assistant Professor of Pediatrics, Harvard Medical School
Pediatric Infectious Disease Division, MassGeneral Hospital for Children
“Primary Care Management of Chronic Conditions in Pediatrics”
Jeanne Van Cleave, MD
Instructor of Pediatrics, Harvard Medical School
Academic General Pediatrics Program, MassGeneral Hospital for Children
“Innate Immunity – Learning on the Fly”
Lynda Stuart, MD
Assistant Professor of Pediatrics, Harvard Medical School
Developmental Immunology Program at MassGeneral Hospital for Children
Poster session awardees:
- Leah Jacoby - Total and site-specific fat and lean mass as predictors of bone density in female adolescent athletes – working with Dr. Madhu Misra in Pediatric Endocrinology at MassGeneral Hospital for Children
- Patricia Rodriguez Bachiller - TGF-ß decreases expression of NO signaling enzymes in the injured newborn lung and in vascular smooth muscle cells -working with Jesse Roberts in the Pediatric ICU at MassGeneral Hospital for Children
- Helena Paidassi - Description of novel innate activation of macrophage: Role in host immunity and intestinal immunopathology - work with Adam Lacy-Hulbert in Development Immunology at MassGeneral Hospital for Children
Research Day 2009
Keynote Lecture: “Genomics and the study of Clinical Diseases”
David Altshuler, MD, PhD
Professor of Genetics and Professor of Medicine, Harvard Medical School
Director, Broad Institute, Program in Medical and Population Genetics
MGHfC Faculty Lectures
“Skeletal Effects of Anorexia Nervosa in Adolescents”
Madhu Misra, MD, MPH
Assistant Professor of Pediatrics, Harvard Medical School
Pediatric Endocrinology, MassGeneral Hospital for Children
“Ironing out the wrinkles in host defense: interactions between innate immunity and iron homeostatis”
Bobby Cherayil, MD
Associate Professor of Pediatrics, Harvard Medical School
Mucosal Immunology Laboratory, Massachusetts General Hospital
“Making a brain in the gut: molecular development of the enteric nervous system”
Allan Goldstein, MD
Associate Professor of Surgery, Harvard Medical School
Pediatric Surgery, MassGeneral Hospital for Children
Poster Session Awardees
- Volodymyr Dzhala (Kevin Staley's lab) - Chloride accumulation and phenobarbital failure in neonatal seizures.
- Marshall Karpel (Emmet Schmidt's lab) - A novel L-ficolin-mannose binding lectin chimeric molecule with enhanced activity against lethal viral infections.
- Jianfeng Wang (David Sweetser's lab) - Groucho/TLE corepressors regulate myeloid differentiation and size of the stem cell/progenitor population

What will we discover next? 
Learn how researchers at MassGeneral Hospital for Children are finding new treatments that advance pediatric care.



