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Presented by the MassGeneral Hospital for Children Research Council annually in the spring, Research Day highlights recent accomplishments and advances from Mass General researchers, as well as from the broader pediatric research community.
The Eighth Annual MassGeneral Hospital for Children Research Day will be held on Tuesday, March 29th, 2016.
Presented by the MGHfC Research Council, MGHfC Research Day highlights recent accomplishments and advances from researchers at MassGeneral Hospital for Children, as well as from the broader pediatric research community.
Steven M. Holland, MD“Gain of Function Immunodeficiencies: Too much of a good thing”Chief, Laboratory of Clinical Infectious DiseasesChief, Immunopathogenesis Section, LCID
Dr. Holland received his MD from the Johns Hopkins University School of Medicine in 1983, where he stayed on as a resident in internal medicine, assistant chief of service in medicine, and fellow in infectious diseases. He joined the National Institutes of Health in 1989 as a National Research Council fellow in the Laboratory of Molecular Microbiology, working on transcriptional regulation of HIV. In 1991, Dr. Holland joined the Laboratory of Host Defenses, shifting his research to the host side, with a focus on phagocyte defects and their associated infections. His work centered on the pathogenesis and management of chronic granulomatous disease, as well as other congenital immune defects affecting phagocytes, including those predisposing to mycobacterial diseases. In 2004, he became chief of LCID.
Additional speakers were prior awardees of the Talbot Pilot Feasibility Study Grant from the MGHfC:
Resident Jack Rowe, MD, presented his research.
“An Overview of Autism Spectrum Disorder” by Christopher J. McDougle, MD, Nancy Lurie Marks Professor of Psychiatry, Director, Lurie Center of Autism
“Is Autism an Autoimmune Disease” by Alessio Fasano, MD, Chief, Division of Pediatric Gastroenterology and Nutrition, Associate Chief, Department of Pediatrics Basic, Clinical and Translational Research, Director, Center for Celiac Research, Director, Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Visiting Professor, Harvard Medical School
MGHfC Faculty Lectures
“Cross-talk between the host and enteric pathogens: what do they talk about and what can go wrong when they do not understand each other”Maria Rosaria Fiorentino, PhDLecturer in Pediatrics
“The Influence of Nutritional Exposures on the Preterm Infant Intestinal Microbiome”Katherine Gregory, PhDClinical Instructor in Pediatrics
“Optimizing health and survival of HIV-exposed children in Botswana through research”Kathleen Powis, MD, MPHInstructor in Pediatrics
Poster Session Awardees
Keynote Lecture: “Molecular Dissection of the new disorder Eosinophilic Esophagitis”Stephanie Seminara, MD, Co-Director of the Reproductive Endocrine Associates, Massachusetts General Hospital, and Associate Professor of Medicine, Harvard Medical School
“Assessing the Safety and Efficacy of Inhaled Nitric Oxide in Cerebral Malaria”Ryan Carroll, MD, Assistant in Pediatrics, MassGeneral Hospital for Children, Instructor in Pediatrics, Harvard Medical School
“The Preterm Infant's Behavioral Pain Response”Kim Francis PhD, RN, PHCNS-BC, Neonatal Clinical Nurse Specialist for the Massachusetts General Hospital Obstetric Service, Clinical Instructor for the MGH Institute of Health Professions, Haley Nurse Fellow for Boston College and Brigham & Women’s Hospital
“Effects of Growth Hormone Augmentation on Visceral Fat and Metabolic Risk in HIV-infection”Takara Stanley, MD, Assistant in Pediatrics, MassGeneral Hospital for Children, Assistant Professor in Pediatrics, Harvard Medical School
Keynote Lecture: “Molecular Dissection of the new disorder Eosinophilic Esophagitis”Marc Rothenberg, MD, PhDDirector of Allergy and Immunology at Cincinnati Children's Hospital Medical Center and the Cincinnati Center for Eosinophilic Disorders
“Immune Therapy in Type 1 Diabetes”Nicole Sherry, MDInstructor in Pediatrics, Harvard Medical SchoolDirector, Diabetes Program, Pediatric Endocrinology, MassGeneral Hospital for Children
“Modulation of Mucosal Immunity by Intestinal Helminth Infection”Haining Shi, DVM, PhDAssistant Professor of Pediatrics, Harvard Medical SchoolMucosal Immunology Laboratory, MassGeneral Hospital for Children
“Use of the Built Environment to Promote Physical Activity in Children”Nicolas Oreskovic, MD, MPHInstructor in Pediatrics, Harvard Medical SchoolInternal Medicine & Pediatrics, Massachusetts General HospitalCenter for Child & Adolescent Health Research and Policy
“Human RAG deficiency: not just immunodeficiency--Novel insights into mechanisms of immune dysregulation”Jolan Walter, MD, PhDClinical Instructor in Pediatrics, Harvard Medical SchoolPhysician, Pediatric Allergy/Immunology, MassGeneral Hospital for Children
Keynote Lecture: “Stem and Progenitor Cells in Neonatal Lung Injury and Repair”Dr. Vivek BalasubramaniamUniv. of Colorado – Director of Pediatric Heart Lung Center
Elahna Paul, MD, PhDInstructor in Pediatrics, Harvard Medical SchoolPediatric Nephrology, MassGeneral Hospital for Children
Jonathan Spector, MDInstructor in Pediatrics, Harvard Medical SchoolNeonatology and Newborn Medicine, MassGeneral Hospital for Children
Ann-Christine Duhaime, MDNicholas T. Zervas Professor of NeurosurgeryPediatric Neurosurgery, MassGeneral Hospital for Children
Keynote Lecture: “Update on Obesity Research”Lee Kaplan, MD, PhD Director, MGH Weight Center
“Immunity to Cholera”Jason Harris, MDAssistant Professor of Pediatrics, Harvard Medical SchoolPediatric Infectious Disease Division, MassGeneral Hospital for Children
“Primary Care Management of Chronic Conditions in Pediatrics”Jeanne Van Cleave, MD Instructor of Pediatrics, Harvard Medical SchoolAcademic General Pediatrics Program, MassGeneral Hospital for Children
“Innate Immunity – Learning on the Fly”Lynda Stuart, MD Assistant Professor of Pediatrics, Harvard Medical SchoolDevelopmental Immunology Program at MassGeneral Hospital for Children
Poster session awardees:
Keynote Lecture: “Genomics and the study of Clinical Diseases”David Altshuler, MD, PhD Professor of Genetics and Professor of Medicine, Harvard Medical SchoolDirector, Broad Institute, Program in Medical and Population Genetics
“Skeletal Effects of Anorexia Nervosa in Adolescents”Madhu Misra, MD, MPH Assistant Professor of Pediatrics, Harvard Medical SchoolPediatric Endocrinology, MassGeneral Hospital for Children
“Ironing out the wrinkles in host defense: interactions between innate immunity and iron homeostatis”Bobby Cherayil, MD Associate Professor of Pediatrics, Harvard Medical SchoolMucosal Immunology Laboratory, Massachusetts General Hospital
“Making a brain in the gut: molecular development of the enteric nervous system”Allan Goldstein, MDAssociate Professor of Surgery, Harvard Medical SchoolPediatric Surgery, MassGeneral Hospital for Children
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