In a research laboratory, at a patient’s bedside, in a student conference with tomorrow’s medical leaders—in fact anywhere on this dynamic campus—our scientists and physicians are diligently working toward improving the lives of children.
Our overall goal is to continue to characterize neural stem cells and to study their role in ENS regeneration in health and response to disease, as well as using the NSCs as possible cell-therapy for various forms of intestinal neuropathy including Hirschsprung’s disease.
Experiments carried out by our group are directed at understanding the mechanisms that regulate intestinal innate immune responses to pathogenic and commensal bacteria.
My laboratory is interested in the development of the enteric nervous system (ENS), a complex neuronal network whose principal function is to maintain normal intestinal motility.
The Goodman lab is dedicated to decreasing the burden of disease, particularly related to obesity, cardiovascular disease and diabetes, among disadvantaged youth, their families and communities.
The Pediatric Airway, Voice, and Swallowing Center, a collaboration of MassGeneral Hospital for Children and the Massachusetts Eye and Ear Infirmary, specializes in conducting research to treat children with voice disorders and airway management symptoms that affect the ability to eat, breathe or speak.
The Teratology Program program focuses on the study of the causes of congenital malformations.
The Misra group studies neuroendocrine and bone alterations in conditions spanning the nutritional spectrum.
Research in the Moskowitz Lab at Massachusetts General Hospital focuses on antibiotic-resistant bacteria such Pseudomonas aeruginosa that cause difficult-to-treat infections in people with cystic fibrosis (CF) or other serious clinical conditions.
The Perrin group studies chronic health conditions in children and adolescents, with particular focus on autism spectrum disorders (ASD).
The Roberts Laboratory is devoted to investigating novel mechanisms and developing new therapies for important pediatric lung diseases.
The Shreffler Laboratory is interested in the mechanisms regulating both primary sensitization and the subsequent balance between immune progression or regulation that determines either clinical sensitivity or tolerance to mucosal allergens.