Pediatric Critical Care Medicine
Summary of Research
Dr. Whalen's research focus is the role of inflammation in the pathogenesi sof traumatic brain injury. Using a mouse model of controlled cortical impact that models features of human TBI such as acute and chronic cell death, brain tissue atrophy, motor deficits, and learning and memory deficits, he seeks to understand how tumor necrosis factor receptor family members play a role in the various deficits in our mouse TBI model. He also studies the role of complement components and other inflammatory pathways. We use adult and immature mouse TBI models, and molecular biological techniques such as gene therapy, transgenic and knockout mice, and others. His is a highly collaborative group and welcome potential ideas from other investigators in the inflammation field.
Contact Information
Phone: 617-724-4380
Fax: 617-724-4391
E-mail: mwhalen@partners.org
