Research Centers

Center for Child & Adolescent Health Research and Policy

Advancing lifelong health within and beyond healthcare settings

Center for Child & Adolescent Health Research and Policy Seminar Series

September 2013 –June 2014
3rd Wednesdays 12:30pm – 1:30pm
100 Cambridge St, 15th Flr, Conference Room 1511B
Complete Schedule (pdf)

The mission of the Massachusetts General Hospital Center for Child & Adolescent Health Research and Policy (CAHRP) is to build the scientific knowledge base in order to provide evidence for effective advocacy, policies and program development that promote the lifelong health and wellbeing of children, their families and the communities in which they live and grow. Through innovative, multilevel research that is based on principles of social justice and the view that child development is a dynamic process of changing interactions between biology, behavior, and the physical and social environment, the Center works to improve lifecourse health development and the quality of systems serving children, families and communities and also to reduce health disparities.

The CAHRP multidisciplinary faculty each have their own research focus and also work collaboratively on projects related to the Center’s mission.

Elizabeth Goodman, MD, Director
The Goodman lab dedicated to decreasing the burden of disease, particularly related to obesity, cardiovascular disease and diabetes, among disadvantaged youth, their families and communities. The lab has two main lines of inquiry: 1) understanding the processes through which differences in social status influence children’s health and the trajectory toward adult cardiovascular health, and 2) developing and evaluating programs which build strengths, encourage civic engagement, and offer opportunities for teens to positively impact both themselves and their environments. Current projects include the PSD Study a longitudinal study of social status impact on health of adolescents and young adults, and IPACE (Intervention and Policy Advocacy for Changing Environments) which conducts community-based research to further knowledge through community partnerships that promote health and sustainable, systemic change. 

Alexy Arauz Boudreau, MD, MPH
Dr. Arauz Boudreau’s interests focus on determining effective means to reduce health disparities for vulnerable children by impacting childhood development both through community and primary care initiatives. A major focus of her research has been directed at how to structure pediatric primary care practices to optimally support child development and school readiness. Current projects include Healthy Living Today, a child-parent intervention to address childhood obesity through an interactive family approach to lifestyle choices with the aid of health coaches working in tandem with primary care providers and projects related to the medical home.

John Patrick T. Co, MD, MPH
Research interests include: 1) The use of information technology, particularly clinical decision support, to improve the quality of care delivered in pediatric primary care practice, 2) Pediatric quality measurement and improvement, and 3) Medical education.  Current research projects include studying the feasibility of integrating electronic medical record, web-based pre-visit screening into the ambulatory setting for identifying and managing pediatric chronic conditions.  Another project is looking at the effect of clinical decision support on the quality of care delivered for neonatal hyperbilirubinemia.

Inyang Isong, MD, MPH, SM
Dr. Isong’s research focuses on evaluating family and community determinants of children's oral health status and access to care, and understanding their role in oral health disparities.

Milton Kotelchuck, PhD, MPH
Dr. Kotelchuck runs the Maternal and Child Health (MCH) life course research laboratory at the CAHRP. The MCH life course research laboratory focuses on better understanding of the impact of  prenatal and obstetric experiences on subsequent child health and development and on maternal and family health. The lab aims to enhance MCH data system capacities, including improvements in the measurement of child morbidities and health disparities and  improve State and national MCH early life programs and policies. Current projects include examination of the impact of Assisted Reproductive Technique conceptions; maternal gestational diabetes recurrence; late preterm (34-36) deliveries; and maternal alcohol and drug abuse and treatment, Down syndrome survival and autism diagnosis. 

Karen Kuhlthau, PhD
The Kuhthau lab’s research aims to improve the lives of children and families through improving clinical care and health care systems particularly in relation to children with special health care needs as well as children with brain tumors and children with autism. The lab uses both quantitative and qualitative methodologies and a variety of data sources. 

Nicolas Oreskovic, MD, MPH
Dr. Oreskovic’s research focuses on how the built environment, including architecture and urban planning, can affect people’s health, particularly how it can affect chronic diseases in children.  He is Principal Investigator for an NIH K 23 Award study, “Children's Use of the Built Environment for physical activity Study (CUBES),” a multidisciplinary study aimed at better understanding where and how children and adolescents use the built environment for physical activity and collaborates on multiple other obesity-related projects.

James Perrin, MD
The Perrin group studies chronic health conditions in children and adolescents, with particular focus on autism spectrum disorders (ASD). Recent work has examined care improvement for children with ASD and racial and ethnic disparities in autism diagnosis and care.  The team also provides evidence to support decision-making regarding newborn genetic screening and has examined recent policy and changes regarding public programs supporting children with disabilities (the Supplemental Security Income [SSI] program).

Jeanne Van Cleave, MD
Current research in our group focuses on how physicians and practices adopt and use new practices, programs and tools over time. Specific projects investigate barriers and facilitators to implementing changes for managing mental health conditions in pediatric primary care. We are also collaborating on a project that investigates how motivated pediatric practices become closer to the ideal "medical home."

Jonathan P. Winickoff, MD, MPH

In General: James M. Perrin, MD

In General awards and honors

The CAHRP publishes the results of its research projects in a broad array of distinguished academic journals, reflecting the interdisciplinary nature of our work. 


Caban AJ, Lee DJ, Goodman E, Davila EP, Fleming LE, LeBlanc WG, Arheart KL, McCollister KE, Christ SL, Zimmerman FJ, Muntaner C, Hollenbeck JA. Health Indicators Among Unemployed and Employed Young Adults. Journal of Occupational and Environmental Medicine, 2011;53:196-203.

Co JPT, Sternberg S, Homer CJ.  Measuring Patient and Family Experiences of Health Care for Children.  Acad Pediatr. 2011; 11 (3 Suppl):S59-67.

Goodman E. Must A, Depressive Symptoms in Severely Obese Compared to Normal Weight Adolescents: Results from a Community-Based Longitudinal Study, J Adolesc Health, 2011;49:64-69.

Isong IA, Silk, H, Rao SR, Perrin JM, Savageau, JA, Donelan, K. Provision of Fluoride Varnish to Medicaid-Enrolled Children by Physicians: The Massachusetts Experience. Health Services Research. DOI: 10.1111/j.1475-6773.2011.01289.x

Kuhlthau KA, Bloom S, Van Cleave J, Knapp AA, Romm D, Klatka K, Homer CJ, Newacheck PW, Perrin JM. Evidence for family-centered care for children with special health care needs: a systematic review. Acad Pediatr. 2011;11(2):136-43.

Kuhlthau K.  Measures of Availability of Health Services for Children. Academic Pediatrics. 2011; 11:s42-s48.

Manning SE, Davin CA, Barfield WD, Kotelchuck M, Clements K, Diop H, Osbahr T, Smith LA. Early diagnoses of autism spectrum disorders in Massachusetts birth cohorts, 2001-2005. Pediatrics. 2011; 127(6):1043-51.

Roberts CL, Ford JB, Algert CS, Antonsen S, Chalmers J, Cnattingius S, Gokhale M, Kotelchuck M, Melve KK, Langridge A, Morris C, Morris JM, Nassar N, Norman JE, Norrie J, Sorensen HT, Walker R, Weir CJ.  Population-based trends in pregnancy hypertension and preeclampsia: An international comparative study. BMJ Open 2011;Published: 2011 doi:10.1136/bmjopen-2011-000101.


Arauz Boudreau A, Fluet C, Reuland C, Delahaye J, Perrin J, Kuhlthau K. Associations of Language and Cultural Competence with Latino Parents’ Views of their Children’s Well-Child Care. Academic Pediatrics. 2010;10(3):172-178.

Berlan, ED, Corliss, HL, Field, AE, Goodman, E, Austin, SB. Sexual Orientation and Bullying among Adolescents in the Growing Up Today Study, J Adolesc Health, 2010;46(4): 366-371

Co JPT, Johnson SA, Poon E, Fiskio J, Rao S, Van Cleave J, Perrin JM, Ferris TG.  Electronic Decision Support and the Quality of Care for Children with Attention Deficit Hyperactivity Disorder. Pediatrics 2010; 126: 239-246.

Davila EP, Christ SL, Caban Martinez A, Lee DJ, Arheart KA, LeBlanc WG, McColllister KE, Clarke T, Zimmerman FJ, Goodman E, Muntaner C, Fleming LE. Young adults, mortality, and employment. J Occup Environ Med. 2010;52(5):501-4.

Emans, SJ, Austin, SB, Goodman, E, Orr, DP, Freeman, R, Stoff, D, Litt, IF, Schuster, MA, Haggerty, R, Granger, R, Irwin, CE. Improving Adolescent and Young Adult Health – Training the Next Generation of Physician Scientists in Transdisciplinary Research, J Adolesc Health,2010;46: 100-109.

Goodman E. Must A, Daniels SR, Dolan LM. Hostility and adiposity mediate disparities in insulin resistance in adolescents and young adults. J Pediatr. 2010; 157:572-577.

Isong IA, Zuckerman KE, Rao SR, Kuhlthau KA, Winickoff JP, Perrin JM. “The Association Between Parents’ and Children’s Use of Oral Health Services.” Pediatrics. 2010;125(3):502-8.

Kuhlthau KA, Orlich F, Hall TA, Sikora D, Kovacs EA, Delahaye J, Clemons TE. Health-related quality of life in children with autism spectrum disorders: results from the Autism Treatment Network. Journal of Autism and Developmental Disorders. 2010; 40: 721-729.

Kuhlthau K, Kahn R, Hill KS, Gnanasekaran S, Ettner SL. The well-being of parental caregivers of children with activity limitations. Maternal and Child Health Journal. 2010; 14:155-163.

Li ST, Paterniti DA, Co JPT, West, DC.  Successful Self-Directed Lifelong Learning in Medicine: A Conceptual Model Derived from Qualitative Analysis of a National Survey of Pediatric Residents. Academic Medicine 2010; 85(7): 1229-36.

Lipstein E, Nabi E, Perrin J, Luff D, Browning M, Kuhlthau K.  Parent decision-making in newborn screening: Opinions, choices and information needs.  Pediatrics, 2010: 126: 696-704.

Oreskovic NM, Kuhlthau KA, Laraque D, Serwint JR, Schuster MA. Health care reform for children: views from the Academic Pediatric Association. Academic Pediatrics, 2010; 10(3): 153-154.

Perrin JM, Knapp AA, Browning MF, Comeau AM, Green NS, Lipstein EA, Metterville DR, Prosser L, Queally D, Kemper AR.  An evidence development process for newborn screening.  Genetics in Medicine, 2010; 12: 131-134.

Van Cleave J, Gortmaker SL, Perrin JM. Dynamics of obesity and chronic health conditions among children and youth. JAMA. 2010; 303(7):623-30.

Winickoff JP, Van Cleave J, Oreskovic NM. Tobacco smoke exposure and chronic conditions of childhood. Pediatrics. 2010; 126(1): e251-252.


Ashe, M. Bennett G, Economos CD, Goodman E, Schilling J, Quintiliani L, Rosenbaum S, Vincent J, Must A Assessment of Coordination of Law-Based Efforts Across Jurisdictions and Sectors for Obesity Prevention and Control. J Law Medicine and Ethics, 2009;37:45-54.

Bethell C, Read D, Goodman E, Johnson J, Besl J, Cooper J, Simpson, LA. Consistently Inconsistent: A Snapshot of Across and Within State Disparities in the Prevalence of Childhood Overweight and Obesity. Pediatrics, 2009;123(Supplement_5):S277-286.

Co JPT, Macdonald E, Yucel RM, Ferris TG, Practice Variation in Parental Assessment of Pediatric Ambulatory Care.  Academic Pediatrics 2009; 9(1): 47-52.

Cooley W, McAllister J, Sherrieb K, Kuhlthau K. Improved outcomes associated with medical home implementation by pediatric primary care practices. Pediatrics. 2009; 124:358-64.

Coury D, Jones NE, Klatka K, Winklosky B, Perrin JM.  Health care for children with autism:  The Autism Treatment Network.  Current Opinion in Pediatrics; 2009; 21:828-832.

Goodman, E, Graham TE, Dolan LM, Daniels SR, Goodman ER, Kahn BB. The Relationship of Retinol Binding Protein 4 to Changes in Insulin Resistance and Cardiometabolic Risk in Overweight Black Adolescents. J Pediatr 2009;154:67-73.

Goodman, E, Li, C, Tu, Y-K, Ford, E, Sun, S, Huang, T. Stability of the Factor Structure of the Metabolic Syndrome across Pubertal Development: Confirmatory Factor Analyses of Three Alternative Models. J Pediatr, 2009; 155(3): S5.e1-S5.e8.

Kogan MD, Blumberg SJ, Schieve LA, Boyle CA, Perrin JM, Ghandour RM, Singh GK, Strickland BB, Trevathan E, Van Dyck PC.  The prevalence of parent-reported diagnosis of autism spectrum disorder among children in the United States, 2007.  Pediatrics.  2009; 124: 1395-1403.

Li, C, Ford, E, Huang, T, Sun,  S, Goodman, E. Patterns of Change in Cardiometabolic Risk Factors Associated with the Metabolic Syndrome Among Children and Adolescents: the Fels Longitudinal Study. J Pediatr, 2009; 155(3):S5.e9-S5.e16.

Lipstein EA, Perrin JM, Waisbren SE, Prosser LA.  Impact of false-positive newborn metabolic screening results on early health care utilization.  Genetics in Medicine, 2009; 11: 716-721.

Must, A, Bennett G, Economos CD, Goodman E, Schilling J, Quintiliani L, Rosenbaum S, Vincent J, Ashe M. Improving Coordination of Law-Based Efforts across Jurisdictions and Sectors for Obesity Prevention and Control. J Law Medicine and Ethics, 2009; 37:90-98.

Newacheck P, Houtrow AJ, Romm DL, Kuhlthau KA, Bloom SR, Van Cleave JM, Perrin JM.  The future of health insurance for children and youth with special health care needs.  Pediatrics, 2009; 123: e940-e947.

Oreskovic NM, Winickoff JP, Kuhlthau KA, Romm D, Perrin JM. Obesity and the built environment among Massachusetts children. Clinical Pediatrics. November, 2009; 48(9): 904-912.

Oreskovic NM, Kuhlthau KA, Romm D, Perrin JM. Built environment and weight disparities among children in high- and low-income towns. Academic Pediatrics; 2009; 9(5): 315-321.

Oreskovic NM, Sawicki GS, Kinane TB, Winickoff JP, Perrin JM. Travel patterns to school among children with asthma. Clinical Pediatrics. 2009;48(6):632-40. Epub 2009.

Rothman RL, Yin HS, Mulvaney S, Co JPT, Homer C, Lannon C.  Health Literacy and Quality: Focus on Chronic Illness Care and Patient Safety.  Pediatrics. 2009; 124 Suppl 3:S315-26.

Zuckerman K, Arauz Boudreau A, Lipstein E, Kuhlthau K, Perrin J . Household Language, Parent Developmental Concerns, and Child Risk for Developmental Disorder. Acad Peds, 2009; 9: 97-105.

Center for Child & Adolescent Health Research and Policy

100 Cambridge Street
15th Floor - C100
Boston, MA 02114

Phone: 617-643-5469
Fax: 617-726-1886

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