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Pediatric Leukemia Clinic

Our leukemia program has state-of-the-art diagnosis and care and access to clinical trials. Our physicians work in consultation with leading hematopathologists and other specialists (blood bank, infectious disease, etc.) and provide compassionate and personalized care for all patients.

Overview

Leukemia is the most common type of cancer diagnosed in children. It is a type of cancer of immature white blood cells that grow out of control and interfere with normal blood cell reduction. This results in anemia and an increased risk for infection and bleeding. Leukemia begins in the  bone marrow, the spongy material in the center of our bones that is the factory for blood cell production.

There are four different types of leukemia in children:

  • Acute lymphoblastic leukemia (ALL) 80%
  • Acute myeloid leukemia (AML) 15%
  • Chronic myeloid leukemia (CML) 2%
  • Juvenile myelomonocytic leukemia (JMMC) 1%

Learn more about leukemia at the National Cancer Institute and CureSearch websites.

Our Approach

Our leukemia program has state-of-the-art diagnosis and care and access to clinical trials. Our physicians work in consultation with leading hematopathologists and other specialists (blood bank, infectious disease, etc.) and provide compassionate and personalized care for all patients.

Expertise in Diagnosing Leukemia

The hematopathologists at Massachusetts General Hospital are world renowned for their expertise in the diagnosis of various types of childhood leukemia. The pathology department has state-of-the-art technology, including

  • Advanced microscopy
  • Flow cytometry for diagnosing subtypes of leukemia and detecting minimal residual disease
  • Cytogenetic  technologies to examine chromosomes of leukemia cells
  • Molecular evaluation of leukemia for diagnostic, prognostic, and research purposes

Research and Clinical Trials

Clinical trials are research studies testing new drugs or combinations of already approved drugs in novel ways. The development of clinical trials over the past 40 years for children with leukemia has led to the high cure rates our patients enjoy today. We work with the Children's Oncology Group (COG), a national pediatric clinical trials group, to develop innovative therapies for childhood leukemia. In addition, we have collaborations with our adult leukemia specialists at Mass General to help identify new drug targets.

Doctors

  • Friedmann, Alison, MD

    617-726-2737

    Accepting New Patients

    Clinical Interests
    • Supportive care of oncology patients
    • Hematologic malignancies (leukemias and lymphomas)
    • Rhabdomyosarcoma / Soft tissue sarcomas
    • ITP
    • Wilm's tumor / Germ cell tumors / Neuroblastoma
    Board Certifications
    • Pediatric Hematology-Oncology, American Board of Pediatrics
    • Pediatrics, American Board of Pediatrics
    Locations
    • Boston: Pediatric Hematology-Oncology
    • Danvers: Mass General/North Shore Center for Outpatient Care
  • Huang, Mary Stephanie, MD

    617-726-2737

    Accepting New Patients

    Clinical Interests
    • Hematology and oncology
    • Hemoglobinopathies
    • Neuroblastomas
    • Pediatric leukemias and lymphomas
    • Late effects and long term follow-up after childhood cancer
    Board Certifications
    • Pediatrics, American Board of Pediatrics
    • Pediatric Hematology-Oncology, American Board of Pediatrics
    Locations
    • Boston: Pediatric Hematology-Oncology
  • Sweetser, David Alan, MD

    617-726-2737

    Accepting New Patients

    Clinical Interests
    • medical genetics
    • Biochemical genetics
    • Genetic basis for birth defects and inherited syndromes
    • Pediatric oncology
    • Hematologic malignancies
    • Inherited syndromes
    • Pitt Hopkins syndrome
    • Hematopoiesis
    • Birth defects
    • Hereditary malformations
    • Inherited cancer predispositions
    Board Certifications
    • Clinical Biochemical Genetics, American Board of Medical Genetics
    • Clinical Genetics (M.D.), American Board of Medical Genetics
    • Pediatric Hematology-Oncology, American Board of Pediatrics
    Locations
    • Boston: Pediatric Hematology-Oncology
    • Boston: Medical Genetics Clinic
    • Danvers: Mass General/North Shore Center for Outpatient Care
  • Weinstein, Howard Jeffrey, MD

    617-726-2737

    Accepting New Patients

    Clinical Interests
    • Pediatric leukemias and lymphomas
    • Childhood solid tumors
    • Stem cell transplantation
    Board Certifications
    • Pediatrics, American Board of Pediatrics
    Locations
    • Boston: Pediatric Hematology-Oncology

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