Immunology & Inflammatory Diseases

View recent publications from investigators of the Center for Immunology and Inflammatory Diseases

HIV-infected T cells are migratory vehicles for viral dissemination

Murooka TT, Deruaz M, Marangoni F, Vrbanac VD, Seung E, von Andrian UH, Tager AM, Luster AD, Mempel TR. Nature 2012; 490: 283-287.

Enhanced Tim3 activity improves survival after influenza infection

Cho JL, Roche MI, Sandall B, Brass AL, Seed B, Xavier RJ, Medoff BD. Journal of Immunology 2012; 189: 2879-2889.

Oral immunotherapy for treatment of egg allergy in children

Burks AW, Jones SM, Wood RA, Fleischer DM, Sicherer SH, Lindblad RW, Stablein D, Henning AK, Vickery BP, Liu AH, Scurlock AM, Shreffler WG, Plaut M, Sampson HA, Consortium of Food Allergy Research (CoFAR). New England Journal of Medicine 2012; 367: 233-243.

T cell homing to epithelial barriers in allergic disease

Islam SA, Luster AD. Nature Medicine 2012; 705-715.

Association of a Toll-like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis

Strle K, Shin JJ, Glickstein LJ, Steere AC. Arthritis and Rheumatism 2012; 64: 1497-1507.

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury

Funke M, Zhao Z, Xu Y, Chun J, Tager AM. American Journal of Respiratory Cell & Molecular Biology 2012; 46: 355-364.

Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation

Sadik CD, Luster AD. Journal of Leukocyte Biology 2012; 91: 207-215.

Systemic discovery of TLR signaling components delineates viral-sensing circuits

Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Anderson MS, Root DE, von Andrian U, Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N. Cell 2011; 147: 853-867.

Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway

Anthony RM, Kobayashi T, Wermeling F, Ravetch JV. Nature 2011; 475: 110-113.

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ Th2 cells

Islam SA, Chang DS, Colvin RA, Byrne MH, McCully ML, Moser B, Lira SA, Charo IF, Luster AD. Nature Immunology 2011; 12: 167-177.

Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma

Castelino FV, Seiders J, Bain G, Brooks SF, King CD, Swaney JS, Lorrain DS, Chun J, Luster AD, Tager AM. Arthritis & Rheumatism 2011; 63: 1405-1415.

Inhibiting CXCR3-dependent CD8+ T cell trafficking enhances tolerance induction in a mouse model of lung rejection

Seung E, Cho JL, Sparwasser T, Medoff BD, Luster AD. Journal of Immunology 2011; 186: 6830-6838.

Rituximab therapy leads to rapid decline of serum IgG4 levels and prompt clinical improvement in IgG4-related systemic disease

Khosroshahi A, Bloch DB, Deshpande V, Stone JH. Arthritis & Rheumatism 2011; 62: 1755-1762.

Synaptotagmin-mediated vesicle fusion regulates cell migration

Colvin RA, Means TK, Diefenbach TJ, Moita LF, Friday RP, Sever S, Campanella GSV, Abrazinski T, Manice LA, Moita C, Andrews NW, Wu D, Hacohen N, Luster AD. Nature Immunology 2011; 11: 495-502.

Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis

Chou RC, Kim ND, Sadik CD, Seung E, Lan Y, Byrne MH, Haribabu B, Iwakura Y, Luster AD. Immunity 2010; 33: 266-278.