Immunology & Inflammatory Diseases

Explore current research programs in the Center for Immunology and Inflammatory Diseases.

Principal Investigators

Robert Anthony, PhD

The Anthony Laboratory investigates the interplay of inflammation and glycosylation, with the intention of engineering and fine tuning immune responses.

Donald Bloch, MD

The Bloch Laboratory investigates the putative infectious agent or agents that initiate autoimmune disease.

Joseph El Khoury, MD

The El Khoury Laboratory investigates the role of the innate immune system in neurodegeneration, inflammation and host defense against infectious pathogens.

Nir Hacohen, PhD

The Hacohen Laboratory investigates the initiation of immune responses, the sensing of pathogens, host-pathogen biology and the development of approaches to discover and model genetic and biochemical networks.

Andrew D. Luster, MD, PhD

The Luster Laboratory investigates chemokines, lipid chemoattractants and their receptors in normal physiology and disease.

Terry Means, PhD

The Means Laboratory combines molecular biology, cellular biology, and genetics to understand the molecular and cellular mechanisms of inflammation and host defense.

Benjamin Medoff, MD

The Medoff Laboratory studies the pathogenesis of pulmonary inflammation, specifically the role of T cells in mediating inflammatory lung diseases.

Thorsten R. Mempel, MD, PhD

The Mempel Laboratory investigates cell migration and intercellular communction in the adaptive immune system through direct dynamic in vivo visualization of immune cell behavior using multiphoton intravital microscopy in mice.

James Moon, PhD

The Moon Laboratory focuses on basic issues of CD4+ T cell tolerance studied by directly tracking antigen-specific populations in mouse and human models.

Wayne Shreffler, MD, PhD

The Shreffler Laboratory is interested in the mechanisms regulating both primary sensitization and the subsequent balance between immune progression or regulation that determines either clinical sensitivity or tolerance to mucosal allergens.

Allen Steere, MD

The Steere Laboratory does translational studies using samples from patients with Lyme arthritis or rheumatoid arthritis to delineate mechanisms involved in the pathogenesis of these diseases, to identify biomarkers of disease activity, and to develop diagnostic tests.

Andrew Tager, MD

The Tager Laboratory investigates (1) pulmonary and dermal fibrosis, focusing on the roles lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), and (2) HIV immunopathogenesis, using a novel mouse model of HIV infection.

Associate Members

Shiv Pillai, MD, PhD

The Pillai Laboratory investigates the biology of the immune system and human genetics.