Principal Investigators

  • Robert Anthony, PhD

    The Anthony Laboratory investigates the role and regulation of immunoglobulin glycosylation.

  • Donald Bloch, MD

    The Bloch Laboratory investigates the role of the bone morphogenetic protein signal transduction pathway in a broad spectrum of human diseases.

  • Shannon Bromley, PhD

    The Bromley Laboratory investigates lymphocyte migration, with an emphasis on the mechanisms that regulate the accumulation of T cells within normal and inflamed non-lymphoid tissues.

  • Joseph El Khoury, MD

    The El Khoury Laboratory investigates the role of the innate immune system in neurodegeneration, inflammation and host defense against infectious pathogens.

  • Sabina Islam, MD

    The Islam Laboratory investigates mechanisms regulating skin immunity and inflammation, and chemokine and associated pathways in chronic skin inflammation and host immunity.

  • Andrew D. Luster, MD, PhD

    The Luster Laboratory investigates chemokines, lipid chemoattractants and their receptors in normal physiology and disease.

  • Terry Means, PhD

    The Means Laboratory combines molecular biology, cellular biology, and genetics to understand the molecular and cellular mechanisms of inflammation and host defense.

  • Benjamin Medoff, MD

    The Medoff Laboratory studies the pathogenesis of pulmonary inflammation in a number of important lung diseases such as asthma, COPD, lung transplant rejection, and viral infections.

  • Thorsten R. Mempel, MD, PhD

    The Mempel Laboratory investigates cell migration and intercellular communction in the adaptive immune system through direct dynamic in vivo visualization of immune cell behavior using multiphoton intravital microscopy in mice.

  • James Moon, PhD

    The Moon Laboratory focuses on basic issues of CD4+ T cell tolerance studied by directly tracking antigen-specific populations in mouse and human models.

  • Wayne Shreffler, MD, PhD

    The Shreffler Laboratory is interested in the mechanisms regulating both primary sensitization and the subsequent balance between immune progression or regulation that determines either clinical sensitivity or tolerance to mucosal allergens.

  • Allen Steere, MD

    The Steere Laboratory does translational studies using samples from patients with Lyme arthritis or rheumatoid arthritis to delineate mechanisms involved in the pathogenesis of these diseases, to identify biomarkers of disease activity, and to develop diagnostic tests.

  • Andrew Tager, MD

    The Tager Laboratory investigates (1) pulmonary and dermal fibrosis, focusing on the roles lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), and (2) HIV immunopathogenesis, using a novel mouse model of HIV infection.

Associate Members

  • Nir Hacohen, PhD

    The Hacohen Laboratory develops new and unbiased strategies to understand basic immune processes and immune-mediated diseases.

  • Shiv Pillai, MD, PhD

    The Pillai Laboratory investigates the biology of the immune system and human genetics.

  • Laurence A. Turka, MD

    The Turka Laboratory investigates the cellular and molecular aspects of T cell tolerance, with a particular interest in mechanisms of transplant tolerance.