Currently Browsing:Imaging

Currently Browsing:Neurology

  • Sleep Division

    The Division of Sleep Medicine at Massachusetts General Hospital provides sophisticated diagnostic testing and comprehensive treatment options for people struggling with any kind of sleep problem.

    MGH Sleep Website Subscribe to Sleep e-Newsletter

    Division of Sleep Medicine: 617-724-7426

Currently Browsing:Obstetrics & Gynecology

  • Midlife Women's Health Center

    The Massachusetts General Hospital Midlife Women’s Health Center brings together experts from more than 15 specialties to improve, promote and advance health care for women at menopause and beyond through research, collaboration and education.

    Contact us: 617-726-6776

    Watch our 2015 community conference

Currently Browsing:Pediatrics

  • Pediatric Sleep Disorders Program

    Sleep problems, including problems falling asleep, staying asleep, disrupted sleep and excessive daytime sleepiness are common in children. The Sleep Disorders Program at MassGeneral Hospital for Children provides comprehensive evaluation and treatment for children with disorders of sleep.

    To schedule an appointment, please call: 888-644-3248

  • Pediatric Pulmonary Medicine

    The Division of Pediatric Pulmonary Medicine at MassGeneral Hospital for Children is a well-established clinical, training and research program. The group provides multidisciplinary comprehensive consultation, diagnostic and management services for a wide array of pulmonary conditions.

    To schedule an appointment, please call: 617-726-8707

Currently Browsing:Pulmonary and Critical Care Medicine

  • Spaulding Sleep Center

    The Spaulding Sleep Center uses the latest technology to diagnose and treat sleep disorders, with a focus on patients with cardiac and/or pulmonary disease.

About This Condition

Restless Legs Syndrome (RLS)

What is RLS?

Restless legs syndrome is a sleep disorder. It causes you to have unpleasant sensations in the legs, which are described as:

  • Creeping
  • Crawling
  • Tingling
  • Pulling

You usually have these sensations in the calf, but they may be felt anywhere from the thigh to the ankle. One or both of your legs may be affected. Some people may have the sensations in the arms. With RLS, you have an irresistible urge to move the affected limb when the sensations occur. Moving often briefly relieves the limb discomfort.

Sleep problems are common with RLS because of the difficulty it causes in getting to sleep. Severe daytime fatigue can also be a big problem.

What causes RLS?

The cause of RLS is still unknown. Some cases are believed to be inherited. Some cases have been linked with nerve damage in the legs due to diabetes, kidney problems, or alcoholism.

As many as one in 10 people in the U.S. may have RLS.

What are the symptoms of RLS?

Sensations occur when you lie down or sit for a prolonged time. This causes:

  • The need to move the legs for temporary relief of symptoms by:
    • Stretching or bending
    • Rubbing the legs
    • Tossing or turning in bed
    • Getting up and pacing
  • Worsening symptoms when lying down, especially when trying to fall asleep at night, or during other forms of inactivity, including just sitting
  • A tendency to feel the most discomfort late in the day and at night

How is RLS diagnosed?

Your doctor can diagnose RLS based on your signs and symptoms, a complete medical history, and a physical exam. In addition, tests, such as lab tests or a sleep study, may be done. Currently, there is not a definitive test to diagnose restless legs syndrome.

How is RLS treated?

Your doctor will consider your age, overall health and other factors when advising treatment for you.

Treatment options for restless legs syndrome may include:

  • Trying good sleep habits
  • Stopping activities that worsen symptoms
  • Avoiding caffeine, alcohol, and tobacco, which may worsen symptoms
  • Regular, moderate exercise
  • Maintaining a well-balanced diet
  • Treating underlying chronic conditions

Medications, including:

  • Dopaminergic agents (drugs that increase dopamine) which are largely used to treat Parkinson's disease
  • Benzodiazepines such as clonazepam and diazepam
  • Opioids such as codeine, propoxyphene, or oxycodone
  • Anticonvulsants such as gabapentin and pregabalin

Consult your doctor for more information regarding the treatment of restless legs syndrome.

Key Points

  • Restless legs syndrome is a sleep disorder that causes unpleasant sensations in the legs. The cause of RLS is still unknown.
  • With RLS, you have an irresistible urge to move the affected limb when the sensations occur.
  • Your doctor can diagnose RLS based on your signs and symptoms, a complete medical history, and a physical exam, but there is no definitive test to diagnose RLS.
  • Medications and lifestyle changes can help relieve RSL symptoms.

Next steps

Tips to help you get the most from a visit to your health care provider:

  • Before your visit, write down questions you want answered.
  • Bring someone with you to help you ask questions and remember what your provider tells you.
  • At the visit, write down the names of new medicines, treatments, or tests, and any new instructions your provider gives you.
  • If you have a follow-up appointment, write down the date, time, and purpose for that visit.
  • Know how you can contact your provider if you have questions.

Clinical Trials

The following related clinical trials and research studies are currently seeking participants at Massachusetts General Hospital. Search for clinical trials and studies in another area of interest.