Conditions & Treatments

Symptoms and Diagnosis of Multiple Pregnancy

Symptoms of multiple pregnancy may include: uterus is larger than expected for the dates in pregnancy, increased morning sickness, increased appetite, excessive weight gain - especially in early pregnancy, or fetal movements felt in different parts of abdomen at same time.

Symptoms and Diagnosis of Multiple Pregnancy

What are the symptoms of multiple pregnancy?

The following are the most common symptoms of multiple pregnancy. However, each woman may experience symptoms differently. Symptoms of multiple pregnancy may include:

  • Uterus is larger than expected for the dates in pregnancy

  • Increased morning sickness

  • Increased appetite

  • Excessive weight gain, especially in early pregnancy

  • Fetal movements felt in different parts of abdomen at same time

How is multiple pregnancy diagnosed?

Many women suspect they are pregnant with more than one baby. Diagnosis of multiple fetuses may be made early in pregnancy, especially if fertility treatments were used. In addition to a complete medical history and physical examination, diagnosis may be made by:

  • Pregnancy blood testing. Levels of human chorionic gonadotrophin (hCG) may be quite high with multiple pregnancy.

  • Alpha-fetoprotein. Levels of a protein released by the fetal liver and found in the mother's blood may be high when more than one fetus is making the protein.

Illustration of a transabdominal ultrasound procedure
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  • Ultrasound. A diagnostic imaging technique that uses high-frequency sound waves to create images of blood vessels, tissues, and organs. Ultrasounds can be done with a vaginal transducer, especially in early pregnancy, or with an abdominal transducer in later pregnancy.

Treatment Programs


Massachusetts General Hospital understands that a variety of factors influence patients' health care decisions. That's just one reason why we're dedicated to ensuring patients understand their diagnosis and treatment options. Because a single option might not serve all patients, we offer a wide range of coordinated treatments and related services across the hospital. Patients should consult with their primary care doctor or other qualified health care provider for medical advice and diagnosis information.

Select a treatment program for more information:



Obstetrics and Gynecology

  • Ultrasound and Prenatal Diagnostics Center
    The Ultrasound and Prenatal Diagnostics Center at Massachusetts General Hospital offers state-of-the-art ultrasound and prenatal diagnostic testing and care, providing a clear picture of your baby’s health before birth.
  • Reproductive Medicine Program
    The Reproductive Medicine Program at the Massachusetts General Hospital Department of Obstetrics and Gynecology provides sophisticated, compassionate care for reproductive health problems, placing the highest emphasis possible on patient safety.
  • Obstetrics Program
    The Obstetrics Program at Massachusetts General Hospital provides state-of-the-art, individualized care for women before, during and after childbirth.

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