The Cardiovascular Research Center at Massachusetts General Hospital


Randall T Peterson

Randall T Peterson

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Lab Overview



Discovering small molecules for use as biological probes and therapeutic agents
Our lab is using chemical and genetic approaches to study embryonic development, especially the formation of blood and the circulatory system. We use high-throughput chemical screens in intact zebrafish to identify small molecules that perturb development or that suppress disease phenotypes in zebrafish models of disease. We are using the small molecules we have discovered to dissect such processes as arterial-venous fate specification, cardiac chamber patterning, and hematopoietic differentiation. Some of the disease-suppressing compounds may also have therapeutic potential and are being developed further using zebrafish and mammalian models of disease.

Recent News

    • Congratulations to Charles Hong for accepting a position as Assistant Professor at
       Vanderbilt University.

    • Congratulations to Quinn Peterson for being accepted into a PhD program at the
       University of Illinois.


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Massachusetts General Hospital the cardiovascular research center