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 Sean Wu |
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Members
Serge Gregoire, Ph.D.
Serge Grégoire attended the University of Sherbrooke in Québec, Canada, from 1999-2001 for his undergraduate training. He majored in biology specializing in biotechnology. This allows him to be recruited in the laboratory of Dr. Xiang-Jiao Yang in the department of Experimental Medicine at McGill University to pursue his Ph.D. training. He studied the molecular regulatory mechanisms of Myocyte Enhancer Factor 2 (MEF2) family of transcription factors. He has shown that histone deacetylase 4 modulates the sumoylation and phosphorylation of MEF2 proteins. This has allowed him to identify a phospho-sumoyl switch. He has demonstrated that this motif is present in more than 80 proteins and that it serves as a valuable signature for in silico identification of proteins regulated by adjacent phosphorylation and sumoylation. More importantly, the proteins identified by such screening play critical roles in cancer formation/progression, cell signaling, stemness, metabolism, and cytoskeletal regulation, highlighting the physiological significance of this motif.
Yuan-Hung Liu, M.D.
Yuan-Hung Liu was graduated from National Taiwan University School of Medicine in Taipei, Taiwan. He subsequently received internal medicine residency and cardiology fellowship training at National Taiwan University Hospital. Yuan-Hung Liu became CV staff at Far Eastern Memorial Hospital in Taipei in July, 2002. He took responsibility of intensive care and resident training in cardiovascular intensive care unit from 2002 to 2003. Being interested in cardiac electrophysiology, he received cardiac electrophysiology (EP) fellowship training at National Taiwan University Hospital from 2003 to 2006, and then set up EP Lab at Far Eastern Memorial Hospital.
He spent most of the time in clinical practice, including patient care, cardiac catheterization, clinical EP, and device implant. Being interested in translational studies of stem cell, he enters cardiovascular research center of MGH as a research fellow.
Esther Yu, B.S.
Esther Yu graduated from Centennial High School in Roswell, GA. She completed her undergraduate training at the Massachusetts Institute of Technology in 2007. Along with majoring in biology at MIT, she worked in the lab of Thijn Brummelkamp at the Whitehead Institute, where she performed RNAi screens to identify and characterize novel genes in various cancer pathways. Furthermore, she investigated methods to use RNAi to selectively target tumorogenic cells.
Min Zeng, M.D.
Min Zeng graduated from the West China University of Medical Science (Sichuan, China). Subsequently she worked in The First affiliated Hospital of The West China University of Medical Science, and Hainan Provincial People's Hospital majoring in cardiology. She participated in the research of the effect evaluation of nasal continuous positive air pressure (n-CPAP) treatment in patient with acute coronary syndrome (ACS) and sleep apnea syndrome (SAS) which was sponsored by Ministry of Health, P.R. China in 2002.And in 2004, she undertook the research financed by Hainan provincial health bureau: A follow up study of incidence of stroke and risk factors in patients with Nonvalvular Atrial Fibrillation(NVAF). Because she has a burgeoning interested in the formation of early stage myocardial lineage commitment by a molecular genetic approach, she joined the Wu lab as a postdoctoral fellow in 2007.
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