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Learn more about news, media coverage and events in diabetes at Massachusetts General Hospital.
An international research team has identified 60 gene variants that can influence blood levels of hemoglobin A1c, measurements of which are used both to diagnose type 2 diabetes and to monitor blood sugar control. One variant found only in African Americans significantly reduces the accuracy of A1c blood testing, increasing the risk of underdiagnosis in a population known to have a higher risk for the disease.
Massachusetts General Hospital investigators have identified a pathway that appears to underlie metformin’s ability both to block the growth of human cancer cells and to extend the lifespan of the C.elegans roundworm, implying that this single pathway plays an important role in a wide range of organisms.
The FDA approval of a phase II clinical trial testing the ability of the generic BCG vaccine to reverse advanced type 1 diabetes was announced today at the 75th Scientific Sessions of the American Diabetes Association by Denise Faustman, MD, PhD, director of the MGH Immunobiology Laboratory and principal investigator of the study.
The latest version of a bionic pancreas device has been successfully tested in two five-day clinical trials – one in adults, the other in adolescents – that imposed minimal restrictions on patient activities.
In the largest study of its kind published to date, an international team of researchers in Mexico and the United States has discovered a strong genetic risk factor for type 2 diabetes that primarily affects Latin American patients, but is rare elsewhere.
An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.
A phase I clinical trial has confirmed that use of a generic vaccine to raise levels of an immune system modulator can cause the death of autoimmune cells targeting the insulin-secreting cells of the pancreas and temporarily restore insulin secretion in human patients with type 1 diabetes.
Massachusetts General Hospital research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some patients years after apparent loss of pancreatic function.
Promising results of a Phase I clinical trial of the generic drug BCG to treat advanced type I diabetes are being announced today at the American Diabetes Association scientific sessions. An MGH research team is describing the apparent reproduction in human patients of a mechanism that reversed type 1 diabetes in a mouse model.
New research finds that gestational diabetes, or pregnancy-related diabetes, may not raise the risk of heart disease independent of other cardiovascular risk factors except in certain high-risk populations.
MGH and the Iacocca Foundation announce today the completion of the Phase I BCG clinical trial in type 1 diabetes, as well as the submission of all safety reports to the U.S. Food and Drug Administration and the MGH data safety monitoring boards.
An artificial pancreas system that closely mimics the body's blood sugar control mechanism was able to maintain near-normal glucose levels without causing hypoglycemia in a small group of patients.
A major international study with leadership from MGH researchers has identified 10 new gene variants associated with blood sugar or insulin levels. Two of these novel variants and three that earlier studies associated with glucose levels were also found to increase the risk of type 2 diabetes.
Intensive lifestyle changes aimed at modest weight loss reduced the rate of developing type 2 diabetes by 34 percent compared with placebo in people at high risk for the disease, researchers conclude based on 10 years of data.
Near-normal control of glucose beginning as soon as possible after diagnosis would greatly improve the long-term prognosis of type 1 diabetes, concludes a study published in the July 27, 2009, issue of the Archives of Internal Medicine, which updates information about the clinical course of type 1 diabetes.
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Risk factors for heart disease include smoking, high blood pressure, diabetes, family history of heart disease and high cholesterol. Learn what you can do to overcome your risk for heart disease.
Michael Jaff, DO, Medical Director of the Massachusetts General Hospital Fireman Vascular Center, says that if you have diabetes, your odds are 1 in 3 of developing peripheral artery disease, with potentially serious consequences. Learn more about why peripheral artery disease often goes undetected, and how it can be diagnosed and treated.
Preparing healthy, flavorful meals doesn't have to be difficult or time consuming. Anne, a nutritionist with the DSME program in Charlestown, demonstrates how to make a quick and easy pasta dish.
Think exercise has to be boring? One of our Diabetes support groups in Chelsea demonstrates how fun and easy exercise can be.
(This video is provided for reference and educational purposes only. Always consult with a qualified and licensed physician prior to beginning any exercise program.)
Wednesday, May 14, 2014
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