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The Massachusetts General Hospital Digestive Healthcare Center offers a multidisciplinary approach to treating and managing the entire spectrum of digestive conditions. Learn how our work impacts patient care.
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Wednesday, May 23, 2007 Research
Researchers from Massachusetts General Hospital and the Broad Institute of MIT and Harvard have found that analysis of a patient’s gut microbiome – the microbial population of the gastrointestinal tract – may predict the likelihood of successful treatment for inflammatory bowel disease with biologic drugs that target immune system activity.
A comprehensive analysis of changes in the intestinal microbial population during the first three years of life has revealed some of the impacts of factors such as mode of birth – vaginal versus cesarean section – and antibiotic exposure, including the effects of multiple antibiotic treatments.
A pilot study has found that a nine-week training program including elicitation of the relaxation response had a significant impact on clinical symptoms of the gastrointestinal disorders irritable bowel syndrome and inflammatory bowel disease and on the expression of genes related to inflammation and the body’s response to stress.
An analysis of genetic and lifestyle data from 10 large epidemiologic studies confirmed that regular use of aspirin or other non-steroidal anti-inflammatory drugs appears to reduce the risk of colorectal cancer in most individuals. The study also found that a few individuals with rare genetic variants do not share this benefit.
MGH investigators have identified the mechanism by which an enzyme produced in the intestinal lining helps to maintain a healthy population of gastrointestinal microbes.
Massachusetts General Hospital, the Broad Institute, and Amgen announced today that they have launched a strategic collaboration to jointly discover and validate new therapeutic targets and develop novel therapies for inflammatory bowel disease, a chronic disorder that affects millions worldwide.
MGH researchers have identified a gene variant that helps predict how much weight an individual will lose after gastric bypass surgery, a finding with the potential both to guide treatment planning and to facilitate the development of new therapeutic approaches to treating obesity and related conditions like diabetes.
Changes in the microbial population of the gastrointestinal tract may underlie some of the benefits of gastric bypass surgery, reports a team of researchers from MGH and Harvard University. The investigators also found that post-bypass alterations in the microbial population of mice can induce weight loss in animals that did not have surgery.
Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall.
A type of immune cell found in the small intestine plays a previously unsuspected role in monitoring antigens circulating in the bloodstream. Disruption of the newly discovered regulatory system may lead to the development of autoimmune disorders, inflammatory bowel disease or food allergies.
New, less invasive treatment using a flexible bracelet of magnetic beads may bring relief with fewer side effects than traditional surgery
Aspirin use appears to reduce the risk of Barrett's esophagus, the largest known risk factor for esophageal cancer.
Massachusetts General Hospital has moved into the number one spot on the 2012-13 U.S. News & World Report’s “America’s Best Hospitals” list.
Regular use of aspirin after colorectal cancer diagnosis may reduce the risk of cancer death, report investigators from Massachusetts General Hospital, Dana-Farber Cancer Institute and Brigham and Women’s Hospital.
A research consortium based at Massachusetts General Hospital has been awarded $15 million from the National Institute of Allergy and Infectious Diseases to investigate how the hepatitis C virus resists suppression and clearance by the immune system.
Massachusetts General Hospital (MGH) researchers are investigating a new way to block reproduction of the hepatitis C virus – targeting not the virus itself but the human genes the virus exploits in its life cycle.
Thursday, April 2, 2015
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Wednesday, February 1, 2012
Thursday, December 6, 2012
Saturday, January 1, 2011
David Ryan, MD, explains the reasons for the current epidemic of esophageal cancer.
David Rattner, MD, explains the management of gastroesophageal reflux, including indications for medical, endoscopy and surgical interventions to control this condition.
Christopher Morse, MD, reviews minimally invasive treatments for esophageal cancer, including esophageal resections. Please note that this video contains images from a real procedure and may cause discomfort for some viewers.
Trailer for the eight-part documentary featuring clinicians at Mass General.
David Rattner, MD, Co-Chief of the Massachusetts General Hospital Digestive Healthcare Center describes how chronic heartburn can lead to other serious conditions, who is most at risk and how Barrett's esophagus and esophageal cancer can be diagnosed and treated.
Liliana G. Bordeianou, MD, a colorectal surgeon at the Massachusetts General Hospital Digestive Healthcare Center says incontinence is not just a normal part of getting older and explains the treatments that can dramatically improve your quality of life.
Milena Weinstein, MD, urogynecologist at the Mass General Department of Obstetrics and Gynecology says urinary incontinence or vaginal bulge can be related to pelvic floor disorders, which affect one out of three women. Learn more about the treatments available for pelvic floor disorders, from exercise to support devices to surgery.
The Campaign for the Third Century of MGH Medicine kicked off Oct. 15 at the Westin Waterfront Boston. Nearly 500 of Mass General’s closest friends and supporters gathered to celebrate the public launch of the fundraising campaign that aims to raise $1.5 billion for the hospital. Already, $1 billion of that amount has been raised.
Since 1811, people have counted on Mass General for answers, innovations and medical leadership. As our third century dawns, we remain ready to serve.
As a burn and critical care fellow at Mass General, Jonathan has worked closely with MGHfC staff. Why is he running to raise money for pediatric cancer care and research? “None of these kids asked for this problem, and neither did their families."
Endoscopic mucosal resection (EMR) is a specialized endoscopic technique used by gastroenterologists at the Massachusetts General Hospital Digestive Healthcare Center to diagnose and remove large areas of early gastrointestinal cancers.
Radiofrequency ablation (RFA) is an FDA-approved endoscopic technique used by specialists at the Massachusetts General Hospital Barrett's Esophagus Treatment Center to treat Barrett's esophagus.
LINX® Reflux Management System is an innovative minimally invasive procedure used by Massachusetts General Hospital surgeons to treat appropriately selected patients experiencing symptoms of gastroesophageal reflux disease (GERD). For more information, visit massgeneral.org/LINX
Per oral endoscopic myotomy (POEM) is a minimally invasive procedure used by surgeons at Massachusetts General Hospital to treat eligible patients experiencing symptoms of achalasia. For more information, visit massgeneral.org/POEM
Minimally invasive esophagectomy (MIE) is a procedure performed by Massachusetts General Hospital surgeons using small incisions to remove a diseased esophagus and reconstruct the gastrointestinal tract. For more information, visit massgeneral.org/MIE
During the procedure, an endoscope with a thin, deflated balloon is inserted through the patient’s mouth and placed into the stomach. The balloon is then filled with sterile saline until it is about the size of a grapefruit, and stays in the stomach for six months. No incisions are made during this nonivasive procedure.
After six months, a nonsurgical procedure, similar to the balloon insertion, is performed to remove the gastric balloon. The balloon is deflated first and then removed.
Wednesday, September 13, 2017
Wednesday, June 21, 2017
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