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Ik-Kyung (IK) Jang, MD, PhD

Director, Clinical Trials Program

  • Phone: 617-726-9226
Departments
Cardiology
Department of Medicine

Specialties

  • Critical Care Center
  • Cardiac Intensive Care Unit
  • Heart Center
  • Interventional Cardiology
  • Coronary Artery Disease Program
Clinical Interests
Acute coronary syndromes
Interventional cardiology
Acute heart attack
Intravascular Imaging
Optical coherence tomography (OCT)
Locations
Boston: Massachusetts General Hospital
Medical Education
MD, Kyung Hee University
Residency, University Hospitals of Leuven
Fellowship, Massachusetts General Hospital
Fellowship, University Hospitals of Leuven
Board Certifications
Cardiovascular Disease, American Board of Internal Medicine
Interventional Cardiology, American Board of Internal Medicine
Gender
Male
Foreign Languages
Dutch
Korean
Patient Age Group
Adult
Accepting New Patients
Yes

BiographyDr. Jang came to Massachusetts General Hospital in 1987 from Leuven University in Belgium, where he has completed his residency in medicine and fellowship in cardiology. He also successfully defended his doctorate thesis at the same university. After his advanced fellowship in cardiology at MGH, he joined the staff and is currently working as a Physician and an interventional cardiologist in the Cardiology Division. He holds currently an academic title of Professor of Medicine at Harvard Medical School.

A recipient of the Partners in Excellence Award for Research in 2000 and for leadership in 2006, his research roster is extensive, and is focused on acute coronary syndromes including acute myocardial infarction. His earlier research focused on pharmacology and physiology of thrombosis and thrombolysis. In 1994 he extended his interests to clinical studies. Since founding the Coronary Clinical Trial Group within the Cardiac Unit in 1995, he has conducted numerous clinical studies. He also led Clinical Research Office of the Cardiology Division between 2003 and 2006. He is currently the Director of the Cardiology Laboratory for Integrative Physiology and Imaging (CLIPI).

For the last eleven years he has pioneered the application of intravascular Optical Coherence Tomography (OCT) to patients to better characterize vulnerable plaque and to understand the mechanisms of plaque rupture. Dr. Jang has been invited to lectures at numerous national and international meetings. His publications number more than 200.

ResearchDr. Jang's research focus has evolved from the pathogenesis and improved management of acute myocardial infarction to the prevention of acute coronary syndromes and sudden cardiac death. His research contributions include:

  • Demonstrating the crucial role of platelets in the sensitivity of the thrombus to thrombolysis. His work provides the groundwork for future research of platelet inhibition therapy for acute coronary syndromes
  • Demonstrating the role of thrombin in thrombosis and thrombolysis, and validating the thrombin hypothesis
  • Organizing and conducting the international, multicenter clinical studies as a principal investigator to improve the treatment of patients with acute myocardial infarction
  • Pioneering a new field of detection of vulnerable coronary plaques using optical coherence tomography (OCT)
Learn more about the Massachusetts General Hospital Optical Coherence Tomography Registry

Publications

View my most recent publications at PubMed

Dr. Jang has a total of 200 publications.

Mass General researchers use optical coherence tomography to identify vulnerable coronary plaques

Mass General researchers are spearheading an international effort to study optical coherence tomography (OCT), an imaging technology that could help doctors identify the vulnerable coronary plaques that cause heart attacks. By creating extremely high-resolution images from within the artery, OCT can pinpoint the microscopic characteristics of a vulnerable plaque.

Optical coherence tomography: view a fly-through image of the coronary arteries

Researchers at Mass General are leading the first optical coherence tomography (OCT) registry, an international database of 3,000 patients who have received OCT. Optical coherence tomography is an intravascular imaging technique that may help physicians identify the vulnerable plaques that lead to heart attacks or sudden cardiac death.

The MGH leads international study to identify vulnerable coronary plaques

MGH Hotline 04.09.10 Optical coherence tomography (OCT) is an intravascular imaging technology that offers the promise of revealing the microscopic characteristics of a vulnerable coronary plaque.

Massachusetts General Hospital to create international registry for coronary optical coherence tomography

Mass General researchers are spearheading an international effort to study optical coherence tomography (OCT), an imaging technology that could help doctors identify the vulnerable coronary plaques that cause heart attacks.

Interventional Cardiology Associates
55 Fruit Street
Boston, MA 02114

Phone: 617-726-9226
Fax: 617-726-7419

Interventional Cardiology Associates
55 Fruit Street
Boston, MA 02114

Phone: 617-726-9226
Fax: 617-726-7419

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