- Clinical Interests
- Infectious diseases
- Medical Education
- MD, Washington University School of Medicine St. Louis
- Residency, Massachusetts General Hospital
- Fellowship, Massachusetts General Hospital
- Board Certifications
- Internal Medicine
- Infectious Disease
- Boston: Massachusetts General Hospital
- Insurances Accepted
- Aetna Health Inc.
- Beech Street
- Blue Cross Blue Shield - Blue Care 65
- Blue Cross Blue Shield - Indemnity
- Blue Cross Blue Shield - Managed Care
- Blue Cross Blue Shield - Partners Plus
- Cigna (PAL #'s)
- Fallon Community HealthCare
- Great-West Healthcare (formally One Health Plan)
- Harvard Pilgrim Health Plan - ACD
- Harvard Pilgrim Health Plan - PBO
- Health Care Value Management (HCVM)
- Humana/Choice Care PPO
- Medicare - ACD
- Neighborhood Health Plan - ACD
- Neighborhood Health Plan - PBO
- OSW - Maine
- OSW - New Hampshire
- OSW - New York
- OSW - Rhode Island
- OSW - Vermont
- Private Health Care Systems (PHCS)
- Railroad Medicare
- Railroad Medicare - ACD
- Senior Whole Health
- Tufts Health Plan
- United Healthcare (non-HMO) - ACD
- United Healthcare (non-HMO) - PBO
- Patient Age Group
- Research Summary
- My laboratory studies the mechanisms and epidemiology of antibiotic resistance in bacteria with a major focus on the molecular determinants of quinolone action and resistance in Staphylococcus aureus and Escherichia coli. The work includes characterization of the regulation of expression, membrane topology, and structure-activity relationships of the NorA and related quinolone efflux transport proteins of S. aureus; genetic dissection of the roles of topoisomerase IV and DNA gyrase in DNA replication, in regulation of virulence gene expression, and as drug targets; epidemiologic analyses of quinolone resistance and factors determining rates of antibiotic resistance in hospitals; molecular determinants favoring clonal spread of vancomycin-resistant Enterococcus faecium; and role of perioperative antibiotic use in selection of resistant bacteria.
Hooper DC. Quinolones. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 7th edition. Philadelphia: Elsevier Churchill Livingstone Inc., 2009; 487-510.
Hooper DC. Urinary tract agents. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 7th edition. Philadelphia: Elsevier Churchill Livingstone Inc., 2009; 515-520.
Peleg AY, Hooper DC. Hospital-acquired infections due to gram-negative bacteria. N. Engl. J. Med. 2010; 362:1804-1813.
Recently, the MGH Center for Global Health convened members of the MGH community for a seminar discussing a range of issues related to the Ebola outbreak, including the latest research, hospital preparedness and reports from the field.
Three innovative teams were honored with this year's Nathaniel Bowditch Prize, which recognized their significant contributions to enhance the delivery of quality patient care while also reducing the cost of that care.
At the MGH, there has been a considerable increase in the number of flu cases in the past several weeks, with health centers, outpatient practices and the Emergency Department reporting seeing an additional 40 to 80 patients a day with flu-like illness.
MGH Hotline 5.22.09 The MGH STOP (Stop Transmission of Pathogens) Task Force recently hosted "Hand Hygiene Day" May 12 to celebrate the hospital reaching a 91/94 percent hand hygiene compliance rate – the practice of proper hand hygiene both before and after contact with the patient or patient's environment – from January through March.
MGH Hotline 5.22.09 The MGH STOP (Stop Transmission of Pathogens) Task Force recently hosted "Hand Hygiene Day" May 12 to celebrate the hospital reaching a 91/94 percent hand hygiene compliance rate -- the practice of proper hand hygiene both before and after contact with the patient or patient's environment -- from January through March.
MGH Hotline 4.3.09 Health care workers know that using an alcohol-based hand rub such as Cal Stat both before and after contact with a patient or a patient's environment is a fast and effective way to reduce health care-associatedinfections.
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