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E Tessa Hedley-Whyte, MD, MBBS

  • Phone: 617-726-5154
Department of Pathology


  • Cancer Center
  • Neuro-Oncology (Brain)
Clinical Interests
Autopsy Pathology
Frozen Section Pathology
Boston: Massachusetts General Hospital
Medical Education
MBBS, Kings College @ University of Durham
MD, Newcastle University
Residency, Children's Hospital Boston
Fellowship, Children's Cancer Research Foundation
Board Certifications
Anatomic Pathology, American Board of Pathology
Neuropathology, American Board of Pathology
Patient Age Group
Accepting New Patients


Massachusetts General Hospital

Professor of Pathology
Harvard Medical School


MGH Center for Aging and Neurodegeneration


Dr. Hedley-Whyte is the co-investigator of the Neuropathology Core of the Massachusetts Alzheimer Disease Research Center (ADRC), established more than 25 years ago as an integral part of the ADRC at MGH. The mission of this Core is to conduct neuropathological examinations on the brains submitted to the Tissue Resource Center and to distribute tissue to ADRC investigators. With Dr. Frosch, we use procedures to enhance the value of these brain tissues to individual investigators whose specific research projects depend upon receiving carefully prepared and diagnosed tissue.

This Neuropathology Core includes investigators with expertise in neuropathology, morphometry, immunocytochemistry, microarray technology, gene chip applications, laser capture techniques and in situ hybridization, as well as expertise in brain banking procedures. We use standardized protocols for tissue acquisition and dissection procedures that ensure complete and reproducible examinations across all cases received. The Tissue Resource Center maintains a rich collection of paraffin blocks and frozen as well as formalin-fixed tissue. The frozen tissue is available both as small blocks and as thin whole coronal brain slices, in which all the anatomical structures are clearly visible. Separate databases within the Brain Tissue Resource Center contain information on tissue availability, location and investigator allocation.

Other research interests include predictive histological markers of pituitary tumor behavior.

Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-726-5154
Phone 2: 617-724-1465
Fax: 617-724-1813

Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-726-5154
Phone 2: 617-724-1465
Fax: 617-724-1813

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