Overview

Dr. Frosch carries forward a long tradition of providing outstanding neurological diagnostic and consulting services to physicians, patients and pathologists in the United States and abroad.

Departments

Pathology

Centers & Specialties

Cancer Center

  • Neuro-Oncology (Brain)
Clinical Interests
  • Neuropathology
  • Autopsy Pathology
  • Frozen Section Pathology
Medical Education
  • MD, Harvard Medical School
  • PhD, Harvard University
  • Residency, Brigham and Women's Hospital
  • Fellowship, Brigham and Women's Hospital
Board Certifications
  • Anatomic Pathology
  • Neuropathology
  • Pathology
Locations
  • Boston: Massachusetts General Hospital
Insurances Accepted
  • Aetna Health Inc.
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • Cigna (PAL #'s)
  • Fallon Community HealthCare
  • Great-West Healthcare (formally One Health Plan)
  • Harvard Pilgrim Health Plan - PBO
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • MassHealth
  • Medicare
  • Medicare - ACD
  • Neighborhood Health Plan - ACD
  • Neighborhood Health Plan - PBO
  • OSW - Connecticut
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - Vermont
  • Private Health Care Systems (PHCS)
  • Railroad Medicare
  • Railroad Medicare - ACD
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Healthcare (non-HMO) - ACD
  • United Healthcare (non-HMO) - PBO

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.

Patient Age Group
Adult
Gender
Male

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Biography

My laboratory is interested in the development and characterization of animal models of human neurodegenerative diseases, particularly Cerebral amyloid angiopathy (CAA), Alzheimer and Parkinson diseases.

In addition to the activities of my laboratory, I am the faculty coordinator for the tissue-based activities of the Harvard NeuroDiscovery Center (HNDC).  We design the implementation of programs that can support tissue-based research into a wide range of neurodegenerative disorders, as pursued across the Harvard neuroscience community (including basic and clinical investigations). Among the resources we have developed is the Advanced Tissue Resource Center, based in Building 114, which includes a staffed Laser Capture Microdissection facility that is available to users.

I direct the Neuropathology Core of the NIA-supported Massachusetts Alzheimer Disease Research Center (MADRC).  The Core provides diagnostic and research-oriented neuropathology autopsy services in support of the Clinical Core of the MADRC.  It also provides tissue to a wide range of researchers within the institution, across the country and internationally.

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Research & Publications

Research Summary

My laboratory is interested in the development and characterization of animal models of human neurodegenerative diseases, particularly Cerebral amyloid angiopathy (CAA), Alzheimer and Parkinson diseases.

In addition to the activities of my laboratory, I am the faculty coordinator for the tissue-based activities of the Harvard NeuroDiscovery Center (HNDC).  We design the implementation of programs that can support tissue-based research into a wide range of neurodegenerative disorders, as pursued across the Harvard neuroscience community (including basic and clinical investigations). Among the resources we have developed is the Advanced Tissue Resource Center, based in Building 114, which includes a staffed Laser Capture Microdissection facility that is available to users.

I direct the Neuropathology Core of the NIA-supported Massachusetts Alzheimer Disease Research Center (MADRC).  The Core provides diagnostic and research-oriented neuropathology autopsy services in support of the Clinical Core of the MADRC.  It also provides tissue to a wide range of researchers within the institution, across the country and internationally.

For more information about research concepts, co-authors, and to see a timeline, visit  Dr. Frosch?s profile at the Harvard Clinical and Translational Science Center. Learn more about research projects on the Frosch Lab site.

Publications

View my most recent publications at PubMed

  1. The INTERnational Study on Primary Angiitis of the CEntral nervous system - a call to the world. Lanthier S, Calabrese LH, Ferro JM, Putaala J, Strbian D, Chagnon M, Frosch MP, Singhal AB, Salvarani C, L?tourneau-Guillon L, Poppe AY, Guilbert F, Raymond J, Muccilli A. Int J Stroke. 2014 Jul; 9(5):E23.
  2. A Novel GRN Mutation (GRN c.708+6_+9delTGAG) in Frontotemporal Lobar Degeneration With TDP-43-Positive Inclusions: Clinicopathologic Report of 6 Cases. Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH.
  3. Tracking the earliest pathologic changes in Alzheimer disease. J Neuropathol Exp Neurol. 2014 May; 73(5):467-73 Landau SM, Frosch MP. Neurology. 2014 May 6; 82(18):1576-7.

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Contact

Pathology Associates
55 Fruit Street
Boston MA, 02114-2696
Phone: 617-726-1265
Fax: 617-724-1813

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