Education: Harvard University BA summa cum laude 1971; Harvard Medical School, MD AOA 1975; Massachusetts General Hospital: Intern and Resident in Internal Medicine 1975-1978; Clinical and Research Fellow in Infectious Diseases 1978-1980; Chief Resident in Medicine 1981; Post-doctoral Research Fellow, Harvard Medical School, 1985-1988
Current Appointments: Chief, Division of Infectious Diseases, Massachusetts General Hospital; Morton N. Swartz MD Academy Professor of Medicine, Harvard Medical School
Other: Chair, Bacteriology and Mycology-1 Study Section, National Institutes of Health (1996-1998); Council, Massachusetts Infectious Disease Society (1999-2005); Chair, Division B (Microbial Pathogenesis) American Society of Microbiology (2000-2001); President, Massachusetts Infectious Disease Society (2001-2003); Vice-Chair, Department of Medicine, Massachusetts General Hospital (2008-); Faculty Dean for Education, Massachusetts General Hospital (2009-); Fellow, American College of Physicians; Fellow, Infectious Diseases Society of America; Fellow, American Academy of Microbiology; Fellow, American Association for the Advancement of Science; Member, Association of American Physicians.
ResearchMy laboratory has two major areas of interest: 1) An NIH-funded program of International Collaborations in Infectious Disease Research, in collaboration with the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, to analyze human mucosal immune responses following natural V. cholerae infection, to analyze gene expression in V. cholerae directly in human samples, to use human immune responses following cholera to identify bacterial genes uniquely expressed during human infection, and to use this information to develop an improved cholera vaccine; 2) Development of live, attenuated strains of V. cholerae as vaccine vectors to deliver heterologous antigens to the common mucosal immune system.
PublicationsOver 150 original publications on topics in microbiology, immunology, and clinical infectious diseases
Carey York-Best, MD, a physician in the Vincent Department of Obstetrics and Gynecology, was honored with the inaugural MGH Bulfinch Student Teaching Award May 7 at a ceremony at Harvard Medical School.
In General awards and honors
Stephen Calderwood, MD, chief of Infectious Diseases and vice chair of the MGH Department of Medicine, was honored with the John T. Potts Jr., MD, Faculty Mentoring Award.
A team of researchers has determined that the strain of cholera erupting in Haiti matches bacterial samples from South Asia and not those from Latin America. The scientists conclude that the bacteria introduced into Haiti most likely came from an infected human, contaminated food or other item from outside of Latin America.
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